Congenital problems
Active cycle of breathing technique for cystic fibrosis | 02-Feb-23 Adrenaline for prevention of morbidity and mortality in preterm infants with cardiovascular compromise | 29-Oct-08 Aerobic exercise training programmes for improving physical and psychosocial health in adults with Down syndrome | 12-May-10 Air versus oxygen for resuscitation of infants at birth | 20-Apr-05 Antibiotic adjuvant therapy for pulmonary infection in cystic fibrosis | 16-Jul-20 Antibiotic prophylaxis regimens and drugs for cesarean section | 06-Dec-11 Antibiotics for brain abscesses in people with cyanotic congenital heart disease | 28-Mar-13 Antifibrinolytic amino acids for upper gastrointestinal bleeding in people with acute or chronic liver disease | 09-Jun-15 Biochemical tests of placental function for assessment in pregnancy | 15-Aug-12 Botulinum toxin A as an adjunct to treatment in the management of the upper limb in children with spastic cerebral palsy (UPDATE) | 20-Jan-10 Botulinum toxin type A in the treatment of lower limb spasticity in children with cerebral palsy | 08-Oct-19 Cancer genetic risk assessment for individuals at risk of familial breast cancer | 15-Feb-12 Carnitine supplementation for inborn errors of metabolism | 15-Feb-12 Clotting factor concentrates given to prevent bleeding and bleeding-related complications in people with hemophilia A or B | 19-Jul-11 Compulsory community and involuntary outpatient treatment for people with severe mental disorders | 17-Mar-17 Constraint‐induced movement therapy in children with unilateral cerebral palsy | 01-Apr-19 Continuous infusion versus intermittent bolus doses of indomethacin for patent ductus arteriosus closure in symptomatic preterm infants | 23-Jan-08 Cooling for newborns with hypoxic ischaemic encephalopathy | 31-Jan-13 Digoxin for preventing or treating neonatal respiratory distress syndrome | 19-Jan-11 Diuretics for respiratory distress syndrome in preterm infants | 07-Dec-11 Dopamine versus no treatment to prevent renal dysfunction in indomethacin‐treated preterm newborn infants | 22-Jul-02 Drug treatment for spinal muscular atrophy type I | 11-Dec-19 Drug treatment for spinal muscular atrophy types II and III | 06-Jan-20 Early (< 7 days) systemic postnatal corticosteroids for prevention of bronchopulmonary dysplasia in preterm infants | 21-Oct-21 Early surfactant administration with brief ventilation vs. selective surfactant and continued mechanical ventilation for preterm infants with or at risk for respiratory distress syndrome | 17-Oct-07 Early volume expansion for prevention of morbidity and mortality in very preterm infants | 19-Apr-04 Effects and safety of periconceptional oral folate supplementation for preventing birth defects | 14-Dec-15 Electropalatography for articulation disorders associated with cleft palate | 08-Jul-09 Enhanced glucose control for preventing and treating diabetic neuropathy | 11-May-12 Enzyme replacement therapy for Anderson‐Fabry disease | 25-Jul-16 Feeding interventions for growth and development in infants with cleft lip, cleft palate or cleft lip and palate | 16-Feb-11 Furosemide for prevention of morbidity in indomethacin‐treated infants with patent ductus arteriosus | 23-Jul-01 Gamma‐aminobutyric acid agonists for antipsychotic‐induced tardive dyskinesia | 17-Apr-18 Gastrostomy feeding versus oral feeding alone for children with cerebral palsy | 31-Jul-13 Heparin for pregnant women with acquired or inherited thrombophilias | 22-Apr-03 Ibuprofen for the prevention of patent ductus arteriosus in preterm and/or low birth weight infants | 27-Jan-20 Ibuprofen for the treatment of patent ductus arteriosus in preterm or low birth weight (or both) infants | 11-Feb-20 Immunoglobulin for preventing respiratory syncytial virus infection | 16-Jun-08 Independent living programmes for improving outcomes for young people leaving the care system | 06-Nov-08 Indomethacin for asymptomatic patent ductus arteriosus in preterm infants | 20-Jan-03 Inhaled nitric oxide for the postoperative management of pulmonary hypertension in infants and children with congenital heart disease | 03-Jul-14 Inhaled versus systemic corticosteroids for preventing bronchopulmonary dysplasia in ventilated very low birth weight preterm neonates | 17-Oct-17 Insoles for prevention and treatment of back pain | 16-Feb-10 Instruments for chorionic villus sampling for prenatal diagnosis | 31-Jan-13 Interactive telemedicine: effects on professional practice and health care outcomes | 07-Sep-15 Interventions for dysphagia in long‐term, progressive muscle disease | 09-Feb-16 Interventions for primary (intrinsic) tracheomalacia in children | 06-Sep-12 Interventions for the management of submucous cleft palate | 19-Jan-16 Interventions for treating brain arteriovenous malformations in adults | 10-Sep-19 Lamotrigine add‐on therapy for drug‐resistant focal epilepsy | 20-Mar-20 Late (≥ 7 days) systemic postnatal corticosteroids for prevention of bronchopulmonary dysplasia in preterm infants | 11-Nov-21 Late versus early surgical correction for congenital diaphragmatic hernia in newborn infants | 23-Oct-00 Magnesium sulphate for preventing preterm birth in threatened preterm labour | 08-Aug-14 Magnesium sulphate for women at risk of preterm birth for neuroprotection of the fetus | 21-Jan-09 Music education for improving reading skills in children and adolescents with dyslexia | 09-Jul-12 Non‐pharmacological interventions for people with epilepsy and intellectual disabilities | 10-Sep-15 Oxcarbazepine add-on for drug-resistant partial epilepsy | 15-Nov-16 Percutaneous lines for delivering intravenous antibiotics in people with cystic fibrosis | 10-Nov-10 Personal assistance for adults (19-64) with both physical and intellectual impairments | 12-Nov-08 Pharmacological and nutritional treatment for McArdle disease (Glycogen Storage Disease type V) | 12-Nov-14 Preconception and antenatal screening for the fragile site on the X‐chromosome | 20-Jan-03 Preimplantation genetic testing for aneuploidies (abnormal number of chromosomes) in in vitro fertilisation | 08-Sep-20 Pre‐operative autologous donation for minimising perioperative allogeneic blood transfusion | 23-Oct-01 Pre-operative endometrial thinning agents before endometrial destruction for heavy menstrual bleeding | 29-Jul-14 Preoperative medical therapy before surgery for uterine fibroids | 15-Nov-17 Pre-operative traction for hip fractures in adults | 11-Oct-11 Prolonged versus short course of indomethacin for the treatment of patent ductus arteriosus in preterm infants | 18-Apr-07 Prophylactic animal derived surfactant extract for preventing morbidity and mortality in preterm infants | 20-Oct-97 Prophylactic antibiotics for preventing gram‐positive infections associated with long‐term central venous catheters in adults and children receiving treatment for cancer | 07-Oct-21 Prophylactic intravenous indomethacin for preventing mortality and morbidity in preterm infants | 07-Jul-10 Prophylactic protein free synthetic surfactant for preventing morbidity and mortality in preterm infants | 20-Jan-10 Prophylactic steroids for pediatric open heart surgery | 21-Oct-15 Prophylactic surgical ligation of patent ductus arteriosus for prevention of mortality and morbidity in extremely low birth weight infants | 23-Jan-08 Protein substitute for children and adults with phenylketonuria | 27-Feb-15 Psychological interventions for depression in adolescent and adult congenital heart disease | 03-Oct-23 Recombinant factor VIIa concentrate versus plasma‐derived concentrates for treating acute bleeding episodes in people with haemophilia and inhibitors | 16-Dec-15 Recombinant factor VIIa for the prevention and treatment of bleeding in patients without haemophilia | 14-Mar-12 Recombinant growth hormone for children and adolescents with Turner syndrome | 05-Nov-08 Removal of nail polish and finger rings to prevent surgical infection | 04-Aug-14 Restricted versus liberal water intake for preventing morbidity and mortality in preterm infants | 04-Dec-14 Second trimester serum tests for Down's Syndrome screening | 13-Jun-12 Secondary bone grafting for alveolar cleft in children with cleft lip or cleft lip and palate | 09-May-11 Selective serotonin reuptake inhibitors (SSRIs) for autism spectrum disorders (ASD) | 08-Aug-13 Speech and language therapy to improve the communication skills of children with cerebral palsy | 19-Apr-04 Subjective barriers to prevent wandering of cognitively impaired people | 22-Jan-01 Superoxide dismutase for preventing chronic lung disease in mechanically ventilated preterm infants | 22-Jan-01 Surgery for congenital choanal atresia | 15-Dec-11 Surgical treatment for the thumb‐in‐palm deformity in patients with cerebral palsy | 19-Oct-05 Surgical versus medical treatment with cyclooxygenase inhibitors for symptomatic patent ductus arteriosus in preterm infants | 28-Mar-13 Synthetic surfactant for respiratory distress syndrome in preterm infants | 27-Jul-98 Thyroid hormone supplementation for the prevention of morbidity and mortality in infants undergoing cardiac surgery | 13-Feb-08 Thyroid hormones for preventing neurodevelopmental impairment in preterm infants | 23-Oct-01 Timing of dornase alfa inhalation for cystic fibrosis | 09-Mar-21 Treadmill interventions in children under six years of age at risk of neuromotor delay | 29-Jul-17 Treatment for mitochondrial disorders | 18-Apr-12 Vagus nerve stimulation for focal seizures | 14-Jul-22 Vitamin K supplementation for cystic fibrosis | 04-Jun-20 Ward reduction without general anaesthesia versus reduction and repair under general anaesthesia for gastroschisis in newborn infants | 16-Mar-10 Zonisamide add‐on therapy for focal epilepsy | 24-Jul-20