Showing 481-500 of 807 for: Essential Evidence Topics Back
- Merkel cell carcinoma
Essential Evidence Topics, 28-Jul-2021
Overall Bottom Line: Examine closely any asymptomatic flesh-colored, pink, red, or blue lesion that a patient states is changing in size, shape, symptoms (itching, tenderness) and is growing rapidly on sun-exposed skin. Perform a full-thickness excision
- Mesenteric adenitis
Essential Evidence Topics, 15-Jun-2021
Overall Bottom Line: The patient frequently presents with acute abdominal pain for which appendicitis must be ruled out. The diagnosis of mesenteric adenitis may be made definitively by the appearance on imaging, or retrospectively after appendicitis ha
- Mesenteric ischemia
Essential Evidence Topics, 28-Jun-2021
Overall Bottom Line: Acute mesenteric ischemia (AMI) is potentially lethal and requires rapid recognition and treatment to prevent death. Suspect it in patients with abdominal pain that is out of proportion to the examination, especially with a history of
- Mesothelioma
Essential Evidence Topics, 3-Dec-2021
Overall Bottom Line: Consider mesothelioma in patients with a history of asbestos exposure and typical symptoms (shortness of breath, chest pain, dullness to percussion). Thoracoscopy with pleural biopsy is recommended for diagnosis. Data showing benef
- Metabolic syndrome
Essential Evidence Topics, 25-Jan-2021
Overall Bottom Line: As part of their cardiovascular risk assessment, patients should be screened for obesity, hypertension, hyperlipidemia, and diabetes. Lifestyle changes such as diet, exercise, and weight loss decrease the eventual laboratory diagnosi
- Metatarsalgia
Essential Evidence Topics, 23-Apr-2022
Overall Bottom Line: Careful clinical evaluation is the most accurate way to make the appropriate diagnosis. MRI and ultrasound are sensitive and highly specific in evaluating patients with metatarsalgia of various etiologies, especially when symptoms p
- Methanol poisoning
Essential Evidence Topics, 16-Feb-2021
Bottom-line: Methanol poisoning should be considered in every patient with severe metabolic acidosis and elevated anion and/or osmolar gaps. To avoid irreversible blindness, treatment should be initiated as soon as possible. IV fomepizole is the antid
- Microscopic colitis
Essential Evidence Topics, 11-Jan-2021
Overall Bottom Line: Patients with microscopic colitis (including collagenous and lymphocytic colitis) present with chronic diarrhea, abdominal pain, flatulence, urgency, and in some cases weight loss and incontinence. Diagnosis is by colonoscopic biops
- Milia
Essential Evidence Topics, 7-Jan-2022
Overall Bottom Line:
- Miscarriage
Essential Evidence Topics, 8-Jun-2021
Overall Bottom Line: Miscarriage is common, occurring in 75% of women during their reproductive lives. Common presentations of miscarriage include vaginal bleeding, lack of fetal heart tones, and abdominal pain. Oral progesterone appears to be effecti
- Mitral insufficiency
Essential Evidence Topics, 17-Jul-2022
Overall Bottom Line: Physical examination is the best initial screening for mitral regurgitation (MR). Echocardiography is useful for diagnosing and monitoring the severity of MR (see ). Medical therapy is reserved for symptomatic patients only and is
- Mitral stenosis
Essential Evidence Topics, 6-Feb-2022
Overall Bottom Line: Most common symptoms are dyspnea, increasing fatigue, orthopnea, or paroxysmal nocturnal dyspnea. Perform echocardiography for the diagnosis of mitral stenosis (MS), for assessment of hemodynamic severity, and to determine suitabili
- Mitral valve prolapse
Essential Evidence Topics, 19-Nov-2021
Overall Bottom Line: Current studies of mitral valve prolapse (MVP) prevalence (0.6% in adults aged 23-35 years) show substantial reductions from past surveys because of a change in diagnostic criteria. The most recent, and largest, meta-analysis on MVP
- Mixed connective tissue disorder
Essential Evidence Topics, 12-Feb-2021
Overall Bottom Line: Suspect mixed connective tissue disorder (MCTD) in any patient, particularly a young woman, who presents with Raynaud's phenomenon and features of other connective tissue diseases. High-titer antiribonucleoprotein (also known as U1-
- Molluscum contagiosum
Essential Evidence Topics, 23-Sep-2021
Overall Bottom Line: Molluscum contagiosum typically presents as single or multiple clusters of pearly, dome-shaped, umbilicated papules. Since molluscum is self-limited, watchful waiting appears to be the best management option for mild, uncomplicated,
- Monoarticular arthritis (diagnostic approach)
Essential Evidence Topics, 23-Mar-2022
Overall Bottom Line: Patient history and physical exam guide the rational use of sequential laboratory and imaging studies for diagnosing monoarticular arthritis. Patients with a history of trauma or focal bone pain require radiographs of the affected joi
- Morton's neuroma
Essential Evidence Topics, 9-Aug-2021
Overall Bottom Line: Patients with Morton's neuroma typically present with interdigital plantar foot pain that becomes worse with walking. They also have pain with pressure to the intermetatarsal space and may have a Mulder's click on exam. Diagnosis is
- Motion sickness
Essential Evidence Topics, 12-Apr-2021
Overall Bottom Line: Any combination of the following symptoms after exposure to motion stimulus (e.g., automobile, airplane, boat, space ship) strongly suggests motion sickness: nausea, vomiting, pallor, cold sweats, hypersalivation, hyperventilation, an
- Multiple endocrine neoplasia (MEN) type 1
Essential Evidence Topics, 2-Aug-2021
Overall Bottom Line: Multiple endocrine neoplasia type 1 (MEN1) is a rare autosomal dominant disorder with high penetrance characterized by parathyroid hyperplasia/adenomas, enteropancreatic neuroendocrine tumors, and pituitary adenomas. Primary hyperpara
- Multiple endocrine neoplasia (MEN) type 2
Essential Evidence Topics, 2-Aug-2021
Overall Bottom Line: Multiple endocrine neoplasia (MEN) type 2 is an autosomal dominant neoplasia syndrome dominated by medullary thyroid cancer (MTC) with high penetrance. It has several variants including familial medullary thyroid cancer (FMTC), MEN 2a
