Showing 1-5 of 5 for: Essential Evidence Topics > Pharmacotherapeutics
- Acetaminophen toxicity
Essential Evidence Topics, 28-Sep-2022
Overall Bottom Line: Address basic life support first, and then obtain an accurate history of quantity, timing, type of ingestion and concomitant ingestions. If within 4 hours of ingestion give activated charcoal. Obtain a stat acetaminophen level and
- Digoxin toxicity
Essential Evidence Topics, 17-Jun-2021
Bottom-line: Suspect digoxin toxicity in patients taking digoxin who present with GI symptoms, visual changes, lethargy, confusion, weakness, or characteristic ECG changes (). Initial assessment should include digoxin level, potassium, and ECG. Monitor re
- Iron toxicity
Essential Evidence Topics, 31-Dec-2021
OVERALL BOTTOM LINE: Most management recommendations are based on case reports, case series, or expert opinion. Children or adults ingesting less than 40 mg/kg can be observed at home. Experts recommend determining the amount of elemental iron ingeste
- Reye's syndrome
Essential Evidence Topics, 29-Nov-2021
Overall Bottom Line: Reye's syndrome is now an uncommon diagnosis; disorders that can present with similar clinical features (such as disorders of fatty acid oxidation or urea cycle defects) are now far more common. Transfer to a pediatric intensive car
- Tardive dyskinesia
Essential Evidence Topics, 10-Jul-2021
Overall Bottom Line: Use neuroleptics only in patients who cannot use other medications and use doses as low as possible. There is some evidence that new antipsychotics may be less likely to cause tardive dyskinesia (TD). Screen patients taking neurol