- Creatine and creatine analogues in hypertension and cardiovascular disease
Cochrane Systematic Reviews, 21-Sep-2011
The creatine kinase system, the central regulatory system of cellular energy metabolism, provides ATP in situ at ATP-ases involved in ion transport and muscle contraction. Furthermore, the enzyme system provides relative protection from tissue ischaemia a - Creatine for amyotrophic lateral sclerosis/motor neuron disease
Cochrane Systematic Reviews, 14-Nov-2012
Creatine, a naturally-occurring nitrogenous organic acid involved in adenosine triphosphate (ATP) production, has been shown to increase survival in mouse models of amyotrophic lateral sclerosis (ALS), also known as motor neuron disease (MND). Results fro - Creatine for Parkinson's disease
Cochrane Systematic Reviews, 16-Jun-2014
Parkinson's disease is one of the most common neurodegenerative disorders and mitochondrial dysfunction plays an important role in its pathogenesis. Creatine is effective in improving mitochondrial function. It may therefore be useful for slowing the prog - Creatine for treating muscle disorders
Cochrane Systematic Reviews, 5-Jun-2013
Progressive muscle weakness is a main symptom of most hereditary and acquired muscle diseases. Creatine improves muscle performance in healthy individuals. This is an update of our 2007 Cochrane review that evaluated creatine treatment in muscle disorders - Creatine for women in pregnancy for neuroprotection of the fetus
Cochrane Systematic Reviews, 16-Dec-2014
Creatine is an amino acid derivative and, when phosphorylated (phosphocreatine), is involved in replenishing adenosine triphosphate (ATP) via the creatine kinase reaction. Cells obtain creatine from a diet rich in fish, meat, or dairy and by endogenous sy - Crisis intervention for people with severe mental illnesses
Cochrane Systematic Reviews, 3-Dec-2015
A particularly difficult challenge for community treatment of people with serious mental illnesses is the delivery of an acceptable level of care during the acute phases of severe mental illness. Crisis-intervention models of care were developed as a poss - Crisis interventions for adults with borderline personality disorder
Cochrane Systematic Reviews, 26-Sep-2022
People diagnosed with borderline personality disorder (BPD) frequently present to healthcare services in crisis, often with suicidal thoughts or actions. Despite this, little is known about what constitutes effective management of acute crises in this pop - Critical incident audit and feedback to improve perinatal and maternal mortality and morbidity
Cochrane Systematic Reviews, 19-Oct-2005
Audit and feedback of critical incidents is an established part of obstetric practice. However, the effect on perinatal and maternal mortality is unclear. The potential harmful effects and costs are unknown. - Cromolyn sodium for the prevention of chronic lung disease in preterm infants
Cochrane Systematic Reviews, 23-Jan-2017
This is an update of a review last published by Cochrane in June 2012 entitled "Cromolyn sodium for the prevention of chronic lung disease in preterm infants", which included two studies. This 2016 update identified no further studies. - Cryoplasty for peripheral arterial disease
Cochrane Systematic Reviews, 9-Aug-2013
Percutaneous balloon angioplasty is an endovascular technique for restoring blood flow through an artery that has become narrowed or blocked by atherosclerosis. Narrowing of the artery following angioplasty (restenosis) is the major cause of long-term fai - Cryotherapy following total knee replacement
Cochrane Systematic Reviews, 15-Aug-2012
Total knee replacement (TKR) is a common intervention for patients with end-stage osteoarthritis of the knee. Post-surgical management may include cryotherapy. However, the effectiveness of cryotherapy is unclear. - Cryotherapy for hepatocellular carcinoma
Cochrane Systematic Reviews, 7-Oct-2009
Hepatocellular carcinoma is the most common primary malignant cancer of the liver. Evidence for the role of cryotherapy in the treatment of hepatocellular carcinoma is controversial. - Cryotherapy for liver metastases
Cochrane Systematic Reviews, 10-Jul-2019
The liver is affected by two of the most common groups of malignant tumours: primary liver tumours and liver metastases from colorectal carcinoma. Liver metastases are significantly more common than primary liver cancer and long-term survival rates report - CSF tau and the CSF tau/ABeta ratio for the diagnosis of Alzheimer's disease dementia and other dementias in people with mild cognitive impairment (MCI)
Cochrane Systematic Reviews, 22-Mar-2017
Research suggests that measurable change in cerebrospinal fluid (CSF) biomarkers occurs years in advance of the onset of clinical symptoms (Beckett 2010). In this review, we aimed to assess the ability of CSF tau biomarkers (t-tau and p-tau) and the CSF t - Cuffed versus uncuffed endotracheal tubes for general anaesthesia in children aged eight years and under
Cochrane Systematic Reviews, 17-Nov-2017
Since the introduction of endotracheal intubation in paediatrics, uncuffed endotracheal tubes (ETTs) have been the standard of care for children under eight years old, based on the presumption that complications, particularly postoperative stridor, are hi - Cuffed versus uncuffed endotracheal tubes for neonates
Cochrane Systematic Reviews, 24-Jan-2022
Endotracheal intubation is a commonly performed procedure in neonates, the risks of which are well-described. Some endotracheal tubes (ETT) are equipped with a cuff that can be inflated after insertion of the ETT in the airway to limit leak or aspiration. - Cultural competence education for health professionals
Cochrane Systematic Reviews, 6-May-2014
Cultural competence education for health professionals aims to ensure all people receive equitable, effective health care, particularly those from culturally and linguistically diverse (CALD) backgrounds. It has emerged as a strategy in high-income Englis - Culturally appropriate health education for people in ethnic minority groups with type 2 diabetes mellitus
Cochrane Systematic Reviews, 28-Aug-2014
Ethnic minority groups in upper-middle-income and high-income countries tend to be socioeconomically disadvantaged and to have a higher prevalence of type 2 diabetes than is seen in the majority population. - Culture media for human pre-implantation embryos in assisted reproductive technology cycles
Cochrane Systematic Reviews, 12-Nov-2015
Many media are commercially available for culturing pre-implantation human embryos in assisted reproductive technology (ART) cycles. It is unknown which culture medium leads to the best success rates after ART. - Culture‐specific programs for children and adults from minority groups who have asthma
Cochrane Systematic Reviews, 22-Aug-2017
People with asthma who come from minority groups often have poorer asthma outcomes, including more acute asthma-related doctor visits for flare-ups. Various programmes used to educate and empower people with asthma have previously been shown to improve ce
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