- Corticosteroids for acute bacterial meningitis
Cochrane Systematic Reviews, 12-Sep-2015
In experimental studies, the outcome of bacterial meningitis has been related to the severity of inflammation in the subarachnoid space. Corticosteroids reduce this inflammatory response. - Corticosteroids for acute ischaemic stroke
Cochrane Systematic Reviews, 7-Sep-2011
The majority of strokes are due to cerebral infarction. Ischaemic cerebral tissue tends to develop cytotoxic oedema which, if the blood-brain barrier is disrupted, may be followed by vasogenic oedema. Large infarcts can develop life-threatening massive oe - Corticosteroids for acute severe asthma in hospitalised patients
Cochrane Systematic Reviews, 22-Jan-2001
Corticosteroids are currently used routinely in the management of acute severe asthma. The optimal dose and route of administration continues to be debated. Some investigators have reported a greater benefit of higher doses of corticosteroids in the manag - Corticosteroids for acute traumatic brain injury
Cochrane Systematic Reviews, 24-Jan-2005
Traumatic brain injury is a leading cause of death and disability. Corticosteroids have been widely used in treating people with traumatic brain injury. - Corticosteroids for adult patients with advanced cancer who have nausea and vomiting (not related to chemotherapy, radiotherapy, or surgery)
Cochrane Systematic Reviews, 3-Jul-2017
Nausea is a common symptom in advanced cancer, with a prevalence of up to 70%. While nausea and vomiting can be related to cancer treatments, such as chemotherapy, radiotherapy, or surgery, a significant number of people with advanced cancer also suffer f - Corticosteroids for aneurysmal subarachnoid haemorrhage and primary intracerebral haemorrhage
Cochrane Systematic Reviews, 4-Aug-2008
Corticosteroids, particularly dexamethasone, are commonly used for treatments in patients with subarachnoid haemorrhage (SAH) and primary intracerebral haemorrhage (PICH) despite the lack of evidence. - Corticosteroids for Bell's palsy (idiopathic facial paralysis)
Cochrane Systematic Reviews, 18-Jul-2016
Inflammation and oedema of the facial nerve are implicated in causing Bell's palsy. Corticosteroids have a potent anti-inflammatory action that should minimise nerve damage. This is an update of a review first published in 2002 and last updated in 2010. - Corticosteroids for cervical ripening and induction of labour
Cochrane Systematic Reviews, 19-Apr-2006
The role of corticosteroids in the process of labour is not well understood. Animal studies have shown the importance of cortisol secretion by the fetal adrenal gland in initiating labour in sheep. Infusion of glucocorticosteroids into the fetus has also - Corticosteroids for chronic inflammatory demyelinating polyradiculoneuropathy
Cochrane Systematic Reviews, 29-Nov-2017
Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is a progressive or relapsing and remitting paralysing illness, probably due to an autoimmune response, which should benefit from corticosteroid treatment. Non-randomised studies suggest tha - Corticosteroids for dengue infection
Cochrane Systematic Reviews, 30-Jun-2014
Dengue is a common and important mosquito-borne viral infection. In many low- and middle-income countries it is endemic and is an important public health problem. Severe dengue is an important cause of death in children. There is no specific treatment for - Corticosteroids for Guillain‐Barré syndrome
Cochrane Systematic Reviews, 24-Oct-2016
Guillain-Barré syndrome (GBS) is an acute paralysing disease caused by inflammation of the peripheral nerves, which corticosteroids would be expected to benefit. - Corticosteroids for HELLP (hemolysis, elevated liver enzymes, low platelets) syndrome in pregnancy
Cochrane Systematic Reviews, 28-Jul-2010
Pre-eclampsia is a relatively common complication of pregnancy. HELLP (hemolysis, elevated liver enzymes, low platelets) syndrome is a severe manifestation of pre-eclampsia with significant morbidity and mortality for pregnant women and their children. Co - Corticosteroids for HELLP syndrome in pregnancy
Cochrane Systematic Reviews, 10-May-2009
Hemolysis, elevated liver enzymes and low platelets (HELLP) syndrome is a severe form of pre-eclampsia. Pre-eclampsia is a multi-system disease of pregnancy associated with an increase in blood pressure and increased perinatal and maternal morbidity and m - Corticosteroids for hospitalised children with acute asthma
Cochrane Systematic Reviews, 20-Jan-2003
Systemic corticosteroids are used routinely in the management of children with severe acute asthma. There is a lack of consensus regarding the agent, dose and route of corticosteroid administration. - Corticosteroids for idiopathic pulmonary fibrosis
Cochrane Systematic Reviews, 21-Jul-2003
Idiopathic pulmonary fibrosis (IPF) is a disease with significant morbidity and mortality. Patients short survival time, high mortality and generally rapid decline raise the importance of early treatment. Current guidelines suggest a combination of cortic - Corticosteroids for maintenance of remission in Crohn's disease
Cochrane Systematic Reviews, 20-Oct-2003
The efficacy of corticosteroids in the setting of maintenance therapy for Crohn's disease has never been clearly demonstrated. It would be important to determine, based upon the currently available data from controlled trials, if the use of chronic cortic - Corticosteroids for managing tuberculous meningitis
Cochrane Systematic Reviews, 28-Apr-2016
Tuberculous meningitis is a serious form of tuberculosis (TB) that affects the meninges that cover a person's brain and spinal cord. It is associated with high death rates and with disability in people who survive. Corticosteroids have been used as an adj - Corticosteroids for myasthenia gravis
Cochrane Systematic Reviews, 20-Apr-2005
Although widely accepted as an appropriate immunosuppressive therapy, the efficacy of glucocorticosteroid treatment has only rarely been tested in controlled studies. This is an update of a Cochrane review first published in 2005 and previously updated in - Corticosteroids for parasitic eosinophilic meningitis
Cochrane Systematic Reviews, 17-Feb-2015
Angiostrongylus cantonensis (A. cantonensis) is the major cause of infectious eosinophilic meningitis. Dead larvae of this parasite cause inflammation and exacerbate symptoms of meningitis. Corticosteroids are drugs used to reduce the inflammation caused - Corticosteroids for periorbital and orbital cellulitis
Cochrane Systematic Reviews, 28-Apr-2021
Periorbital and orbital cellulitis are infections of the tissue anterior and posterior to the orbital septum, respectively, and can be difficult to differentiate clinically. Periorbital cellulitis can also progress to become orbital cellulitis.
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