- Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Hypertension is a major public health challenge affecting more than one billion people worldwide; it disproportionately affects populations in low- and middle-income countries (LMICs), where health systems are generally weak. The increasing prevalence of - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
The prevalence of substance use, both prescribed and non-prescribed, is increasing in many areas of the world. Substance use by women of childbearing age contributes to increasing rates of neonatal abstinence syndrome (NAS). Neonatal opioid withdrawal syn - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Plasmodium vivax (P vivax) is a focus of malaria elimination. It is important because P vivax and Plasmodium falciparum infection are co-endemic in some areas. There are asymptomatic carriers of P vivax, and the treatment for P vivax and Plasmodium ovale - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Transient tachypnoea of the newborn (TTN) is characterized by tachypnoea and signs of respiratory distress. Transient tachypnoea typically appears within the first two hours of life in term and late preterm newborns. The administration of corticosteroids - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Catamenial epilepsy describes a worsening of seizures in relation to the menstrual cycle and may affect around 40% of women with epilepsy. Vulnerable days of the menstrual cycle for seizures are perimenstrually (C1 pattern), at ovulation (C2 pattern), and - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Granulocyte-colony stimulating factor (G-CSF) seems to play an important role in the process of embryo implantation and continuation of pregnancy. It has been used during in vitro fertilisation (IVF) treatment for subfertile women with chronically thin en - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Urinary incontinence in women is associated with poor quality of life and difficulties in social, psychological and sexual functioning. The condition may affect up to 15% of middle-aged or older women in the general population. Conservative treatments suc - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Point-of-care sonography (POCS) has emerged as the screening modality of choice for suspected body trauma in many emergency departments worldwide. Its best known application is FAST (focused abdominal sonography for trauma). The technology is almost ubiqu - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Delirium is a very common condition associated with significant morbidity, mortality, and costs. Current critical care guidelines recommend first and foremost the use of nonpharmacological strategies in both the prevention and treatment of delirium. Pharm - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
The presence of oesophageal varices is associated with the risk of upper gastrointestinal bleeding. Endoscopic variceal ligation is used to prevent this occurrence but the ligation procedure may be associated with complications. - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Cardiovascular disease (CVD) is a major cause of disability and mortality globally. Premature fatal and non-fatal CVD is considered to be largely preventable through the control of risk factors via lifestyle modifications and preventive medication. Lipid- - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Intradialytic hypotension (IDH) is a common complication of haemodialysis (HD), and a risk factor of cardiovascular morbidity and death. Several clinical studies suggested that reduction of dialysate temperature, such as fixed reduction of dialysate tempe - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Down's syndrome occurs when a person has three copies of chromosome 21 (or the specific area of chromosome 21 implicated in causing Down's syndrome) rather than two. It is the commonest congenital cause of mental disability. Non-invasive screening based o - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Multiparametric magnetic resonance imaging (MRI), with or without MRI-targeted biopsy, is an alternative test to systematic transrectal ultrasonography-guided biopsy in men suspected of having prostate cancer. At present, evidence on which test to use is - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Shared decision-making is important in child and adolescent healthcare because there is growing international recognition of children and young people's rights to be included in decisions that affect them. In order for young people to participate effectiv - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Nutritional rickets is a disease which affects children, especially in low- and middle-income countries. It causes problems such as skeletal deformities and impaired growth. The most common cause of nutritional rickets is vitamin D deficiency. Vitamin D a - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
The diagnosis and treatment of a brain or spinal cord tumour can have a huge impact on the lives of patients and their families with family caregiving often resulting in considerable burden and distress. Meeting the support needs of family caregivers is c - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Biologic disease-modifying anti-rheumatic drugs (DMARDs: referred to as biologics) are effective in treating rheumatoid arthritis (RA), however there are few head-to-head comparison studies. Our systematic review, standard meta-analysis and network meta-a - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Pain is a common symptom with cancer, and 30% to 50% of all people with cancer will experience moderate to severe pain that can have a major negative impact on their quality of life. Opioid (morphine-like) drugs are commonly used to treat moderate or seve - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
School dental screening refers to visual inspection of children’s oral cavity in a school setting followed by making parents aware of their child’s current oral health status and treatment needs. Screening at school intends to identify children at an earl
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