- Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Chronic musculoskeletal pain is a prevalent condition and a major cause of disability and absence from the workplace worldwide. Opioids are frequently used to treat chronic pain, although adverse effects often restrict their long-term benefits. Tapentadol - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
There is increasing evidence that both green and black tea are beneficial for cardiovascular disease (CVD) prevention. - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Vitrectomy surgery is one of the commonest ophthalmic procedures performed across the world. It may be performed using general or local anaesthesia encompassing regional or topical anaesthesia depending on a number of factors, including patient suitabilit - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
People with haematological disorders are frequently at risk of severe or life-threatening bleeding as a result of thrombocytopenia (reduced platelet count). This is despite the routine use of prophylactic platelet transfusions to prevent bleeding once the - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Erysipelas and cellulitis (hereafter referred to as 'cellulitis') are common bacterial skin infections usually affecting the lower extremities. Despite their burden of morbidity, the evidence for different prevention strategies is unclear. - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Acute graft-versus-host disease (aGvHD) is a major cause of morbidity and mortality after haematopoietic stem cell transplantation (HSCT) occurring in 8% to 59% of the recipients. Currently, the therapeutic mainstay for aGvHD is corticosteroids. However, - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Stroke is one of the leading causes of disability worldwide and aphasia among survivors is common. Current speech and language therapy (SLT) strategies have only limited effectiveness in improving aphasia. A possible adjunct to SLT for improving SLT outco - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
High altitude illness (HAI) is a term used to describe a group of cerebral and pulmonary syndromes that can occur during travel to elevations above 2500 metres ( ˜ 8200 feet ). Acute hypoxia, acute mountain sickness (AMS), high altitude cerebral oedema (H - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Bronchial thermoplasty is a procedure that consists of the delivery of controlled radiofrequency-generated heat via a catheter inserted into the bronchial tree of the lungs through a flexible bronchoscope. It has been suggested that bronchial thermoplasty - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Increasingly, cancer is recognised as a chronic condition with a growing population of informal caregivers providing care for cancer patients. Informal caregiving can negatively affect the health and well-being of caregivers. We need a synthesised account - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Percutaneous exposure injuries from devices used for blood collection or for injections expose healthcare workers to the risk of blood borne infections such as hepatitis B and C, and human immunodeficiency virus (HIV). Safety features such as shields or r - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Whilst carrying out dental procedures under general anaesthesia (GA), practitioners routinely give local anaesthetics (LA) intraoperatively to children. Local anaesthetics are used to help manage postoperative pain and reduce bleeding and the physiologica - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Nicotinic acid (niacin) is known to decrease LDL-cholesterol, and triglycerides, and increase HDL-cholesterol levels. The evidence of benefits with niacin monotherapy or add-on to statin-based therapy is controversial. - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
According to international guidelines and literature, all patients with intermittent claudication should receive an initial treatment of cardiovascular risk modification, lifestyle coaching, and supervised exercise therapy. In the literature, supervised e - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
People with serious mental illness have rates of Human Immuno-deficiency Virus (HIV) infection higher than expected in the general population for the same demographic area. Despite this elevated prevalence, UK national strategies around sexual health and - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Stroke is one of the leading causes of disability worldwide. Functional impairment, resulting in poor performance in activities of daily living (ADL) among stroke survivors is common. Current rehabilitation approaches have limited effectiveness in improvi - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Clinicians typically select the antibiotics used to treat pulmonary infections in people with cystic fibrosis based on the results of antimicrobial susceptibility testing performed on bacteria traditionally grown in a planktonic mode (grown in a liquid). - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Postoperative pancreatic fistula is one of the most frequent and potentially life-threatening complications following pancreatic resections. Fibrin sealants have been used in some centers to reduce postoperative pancreatic fistula. However, the use of fib - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Gamma aminobutyric acid (GABA) receptor agonists have been shown to have a neuroprotectant effect in reducing infarct size and improving functional outcome in animal models of cerebrovascular disease. However, the sedative effects of GABA receptor agonist - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Erythropoiesis-stimulating agents (ESAs) are commonly used to treat chemotherapy-induced anemia (CIA). However, about half of patients do not benefit.
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