- Comparison of different human papillomavirus (HPV) vaccine types and dose schedules for prevention of HPV‐related disease in females and males
Cochrane Systematic Reviews, 22-Nov-2019
Uptake of human papillomavirus (HPV) vaccine remains low in many countries, although the bivalent and quadrivalent HPV vaccines given as a three-dose schedule are effective in the prevention of precancerous lesions of the cervix in women. Simpler immunisa - Comparison of different platelet count thresholds to guide administration of prophylactic platelet transfusion for preventing bleeding in people with haematological disorders after myelosuppressive chemotherapy or stem cell transplantation
Cochrane Systematic Reviews, 18-Nov-2015
Platelet transfusions are used in modern clinical practice to prevent and treat bleeding in people who are thrombocytopenic due to bone marrow failure. Although considerable advances have been made in platelet transfusion therapy in the last 40 years, som - Comparison of different platelet transfusion thresholds prior to insertion of central lines in patients with thrombocytopenia
Cochrane Systematic Reviews, 2-Dec-2015
Patients with a low platelet count (thrombocytopenia) often require the insertion of central lines (central venous catheters (CVCs)). CVCs have a number of uses; these include: administration of chemotherapy; intensive monitoring and treatment of critical - Comparison of different protein concentrations of human milk fortifier for promoting growth and neurological development in preterm infants
Cochrane Systematic Reviews, 20-Nov-2020
Human milk alone may provide inadequate amounts of protein to meet the growth requirements of preterm infants because of restrictions in the amount of fluid they can tolerate. It has become common practice to feed preterm infants with breast milk fortifie - Comparison of different regimens of proton pump inhibitors for acute peptic ulcer bleeding
Cochrane Systematic Reviews, 12-Jun-2013
Treatment with proton pump inhibitors (PPIs) improves clinical outcomes in patients with peptic ulcer bleeding. However, the optimal dose and route of administration of PPIs remains controversial. - Comparison of first‐line chemotherapy including escalated BEACOPP versus chemotherapy including ABVD for people with early unfavourable or advanced stage Hodgkin lymphoma
Cochrane Systematic Reviews, 25-May-2017
There are two different international standards for the treatment of early unfavourable and advanced stage Hodgkin lymphoma (HL): chemotherapy with escalated BEACOPP (bleomycin/etoposide/doxorubicin/cyclophosphamide/vincristine/procarbazine/prednisone) re - Comparison of routes for achieving parenteral access with a focus on the management of patients with Ebola virus disease
Cochrane Systematic Reviews, 25-Feb-2015
Dehydration is an important cause of death in patients with Ebola virus disease (EVD). Parenteral fluids are often required in patients with fluid requirements in excess of their oral intake. The peripheral intravenous route is the most commonly used meth - Comparison of speech and language therapy techniques for speech problems in Parkinson's disease
Cochrane Systematic Reviews, 15-Aug-2012
Patients with Parkinson's disease commonly suffer from speech and voice difficulties such as impaired articulation and reduced loudness. Speech and language therapy (SLT) aims to improve the intelligibility of speech with behavioural treatment techniques - Comparisons of approaches to pelvic floor muscle training for urinary incontinence in women
Cochrane Systematic Reviews, 3-Nov-2011
Pelvic floor muscle training is the most commonly recommended physical therapy treatment for women with stress urinary incontinence. It is also sometimes recommended for mixed and, less commonly, urge urinary incontinence. The supervision and content of p - Competitions for smoking cessation
Cochrane Systematic Reviews, 20-Feb-2019
Competitions might encourage people to undertake and/or reinforce behaviour change, including smoking cessation. Competitions involve individuals or groups having the opportunity to win a prize following successful cessation, either through direct competi - Complement inhibitors for age-related macular degeneration
Cochrane Systematic Reviews, 9-Jan-2014
Given the relatively high prevalence of age-related macular degeneration (AMD) and the increased incidence of AMD as populations age, the results of trials of novel treatments are awaited with much anticipation. The complement cascade describes a series o - Complementary and alternative therapies for pain management in labour
Cochrane Systematic Reviews, 18-Oct-2006
Many women would like to avoid pharmacological or invasive methods of pain management in labour and this may contribute towards the popularity of complementary methods of pain management. This review examined currently available evidence supporting the us - Complementary and alternative therapies for post‐caesarean pain
Cochrane Systematic Reviews, 1-Sep-2020
Pain after caesarean sections (CS) can affect the well-being of the mother and her ability with her newborn. Conventional pain-relieving strategies are often underused because of concerns about the adverse maternal and neonatal effects. Complementary alte - Complementary and miscellaneous interventions for nocturnal enuresis in children
Cochrane Systematic Reviews, 8-Nov-2011
Nocturnal enuresis (bedwetting) is a socially disruptive and stressful condition which affects around 15% to 20% of five year olds, and up to 2% of young adults. - Complementary therapies for acne vulgaris
Cochrane Systematic Reviews, 19-Jan-2015
Acne is a chronic skin disease characterised by inflamed spots and blackheads on the face, neck, back, and chest. Cysts and scarring can also occur, especially in more severe disease. People with acne often turn to complementary and alternative medicine ( - Complete versus culprit‐only revascularisation in ST elevation myocardial infarction with multi‐vessel disease
Cochrane Systematic Reviews, 3-May-2017
Multi-vessel coronary disease in people with ST elevation myocardial infarction (STEMI) is common and is associated with worse prognosis after STEMI. Based on limited evidence, international guidelines recommend intervention on only the culprit vessel dur - Complex behavioural and educational interventions for nocturnal enuresis in children
Cochrane Systematic Reviews, 13-May-2008
Nocturnal enuresis (bedwetting) is a socially disruptive and stressful condition which affects around 15 to 20% of five-year olds, and up to 2% of young adults. - Complex interventions for preventing diabetic foot ulceration
Cochrane Systematic Reviews, 24-Aug-2015
Ulceration of the feet, which can lead to the amputation of feet and legs, is a major problem for people with diabetes mellitus, and can cause substantial economic burden. Single preventive strategies have not been shown to reduce the incidence of foot ul - Compliance therapy for schizophrenia
Cochrane Systematic Reviews, 19-Jul-2006
Schizophrenia is a severe mental illness characterised by delusions and hallucinations. Antipsychotic drugs does reduce these symptoms, but at least half of people given these drugs do not comply with the treatment regimen prescribed. - Comprehensive Geriatric Assessment for community‐dwelling, high‐risk, frail, older people
Cochrane Systematic Reviews, 6-May-2022
Comprehensive Geriatric Assessment (CGA) is a multidimensional interdisciplinary diagnostic process focused on determining an older person's medical, psychological and functional capability in order to develop a co-ordinated and integrated care plan. CGA
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