- Computed tomography versus magnetic resonance imaging versus bone scintigraphy for clinically suspected scaphoid fractures in patients with negative plain radiographs
Cochrane Systematic Reviews, 5-Jun-2015
In clinically suspected scaphoid fractures, early diagnosis reduces the risk of non-union and minimises loss in productivity resulting from unnecessary cast immobilisation. Since initial radiographs do not exclude the possibility of a fracture, additional - Computer and mobile technology interventions for self‐management in chronic obstructive pulmonary disease
Cochrane Systematic Reviews, 23-May-2017
Chronic obstructive pulmonary disease (COPD) is characterised by airflow obstruction due to an abnormal inflammatory response of the lungs to noxious particles or gases, for example, cigarette smoke. The pattern of care for people with moderate to very se - Computer and mobile technology interventions to promote medication adherence and disease management in people with thalassemia
Cochrane Systematic Reviews, 28-Jun-2019
Thalassemia syndromes are inherited hemoglobin disorders that result when the synthesis of normal hemoglobin is lacking or significantly reduced. For people with thalassemia, long-term red blood cell transfusion remains the mainstay of therapy, which may - Computer‐assisted diagnosis techniques (dermoscopy and spectroscopy‐based) for diagnosing skin cancer in adults
Cochrane Systematic Reviews, 4-Dec-2018
Early accurate detection of all skin cancer types is essential to guide appropriate management and to improve morbidity and survival. Melanoma and cutaneous squamous cell carcinoma (cSCC) are high-risk skin cancers which have the potential to metastasise - Computer‐assisted surgery for knee ligament reconstruction
Cochrane Systematic Reviews, 3-Sep-2014
Anterior cruciate ligament (ACL) reconstruction is one of the most frequently performed orthopaedic procedures. The most common technical cause of reconstruction failure is graft malpositioning. Computer-assisted surgery (CAS) aims to improve the accuracy - Computer-assisted versus oral-and-written dietary history taking for diabetes mellitus
Cochrane Systematic Reviews, 7-Dec-2011
Diabetes is a chronic illness characterised by insulin resistance or deficiency, resulting in elevated glycosylated haemoglobin A1c (HbA1c) levels. Diet and adherence to dietary advice is associated with lower HbA1c levels and control of disease. Dietary - Computer-assisted versus oral-and-written family history taking for identifying people with elevated risk of type 2 diabetes mellitus
Cochrane Systematic Reviews, 4-Nov-2011
Diabetes is a chronic illness characterised by insulin resistance or deficiency, resulting in elevated glycosylated haemoglobin A1c (HbA1c) levels. Because diabetes tends to run in families, the collection of data is an important tool for identifying peop - Computer‐based diabetes self‐management interventions for adults with type 2 diabetes mellitus
Cochrane Systematic Reviews, 28-Mar-2013
Diabetes is one of the commonest chronic medical conditions, affecting around 347 million adults worldwide. Structured patient education programmes reduce the risk of diabetes-related complications four-fold. Internet-based self-management programmes have - Computer‐based versus in‐person interventions for preventing and reducing stress in workers
Cochrane Systematic Reviews, 30-Aug-2017
Chronic exposure to stress has been linked to several negative physiological and psychological health outcomes. Among employees, stress and its associated effects can also result in productivity losses and higher healthcare costs. In-person (face-to-face) - Computer‐generated reminders delivered on paper to healthcare professionals: effects on professional practice and healthcare outcomes
Cochrane Systematic Reviews, 6-Jul-2017
Clinical practice does not always reflect best practice and evidence, partly because of unconscious acts of omission, information overload, or inaccessible information. Reminders may help clinicians overcome these problems by prompting them to recall info - Computerised cognitive training for 12 or more weeks for maintaining cognitive function in cognitively healthy people in late life
Cochrane Systematic Reviews, 27-Feb-2020
Increasing age is associated with a natural decline in cognitive function and is the greatest risk factor for dementia. Cognitive decline and dementia are significant threats to independence and quality of life in older adults. Therefore, identifying inte - Computerised cognitive training for maintaining cognitive function in cognitively healthy people in midlife
Cochrane Systematic Reviews, 13-Mar-2019
Normal aging is associated with changes in cognitive function that are non-pathological and are not necessarily indicative of future neurocognitive disease. Low cognitive and brain reserve and limited cognitive stimulation are associated with increased ri - Computerised cognitive training for preventing dementia in people with mild cognitive impairment
Cochrane Systematic Reviews, 13-Mar-2019
The number of people living with dementia is increasing rapidly. Clinical dementia does not develop suddenly, but rather is preceded by a period of cognitive decline beyond normal age-related change. People at this intermediate stage between normal cognit - Computerized advice on drug dosage to improve prescribing practice
Cochrane Systematic Reviews, 7-Nov-2013
Maintaining therapeutic concentrations of drugs with a narrow therapeutic window is a complex task. Several computer systems have been designed to help doctors determine optimum drug dosage. Signi?cant improvements in health care could be achieved if comp - Concomitant atrial fibrillation surgery for people undergoing cardiac surgery
Cochrane Systematic Reviews, 22-Aug-2016
People with atrial fibrillation (AF) often undergo cardiac surgery for other underlying reasons and are frequently offered concomitant AF surgery to reduce the frequency of short- and long-term AF and improve short- and long-term outcomes. - Concomitant chemotherapy and radiation therapy for cancer of the uterine cervix
Cochrane Systematic Reviews, 20-Jul-2005
The National Cancer Institute (USA) alert in February 1999 stated that concomitant chemoradiotherapy should be considered for all patients with cervical cancer, based on evidence from five randomised controlled trials (RCTs). - Concomitant hydroxyurea plus radiotherapy versus radiotherapy for carcinoma of the uterine cervix
Cochrane Systematic Reviews, 26-Jan-2004
A number of randomised studies suggest hydroxyurea given alongside radiotherapy improves survival in patients with locally advanced cervix cancer. Following publication of five large randomised trials in 1999 and 2000 concomitant chemoradiotherapy has bec - Concomitant hyperthermia and radiation therapy for treating locally advanced rectal cancer
Cochrane Systematic Reviews, 8-Jul-2009
Surgery has been the treatment of choice for patients with rectal cancer. For locally advanced cancer results were poor, with high rates of locoregional recurrences and poor overall survival data. Adding (chemo)radiotherapy upfront improved results mainly - Concurrent chemoradiotherapy in non-small cell lung cancer
Cochrane Systematic Reviews, 5-May-2010
This is an updated version of the original review published in Issue 4, 2004. The use of concurrent chemotherapy and radiotherapy in non-small cell lung cancer (NSCLC) might be seen as a way of increasing the effectiveness of radical radiotherapy at the s - Condom effectiveness in reducing heterosexual HIV transmission
Cochrane Systematic Reviews, 21-Jan-2002
The amount of protection that condoms provide for HIV and other sexually transmitted infections is unknown. Cohort studies of sexually active HIV serodiscordant couples with follow-up of the seronegative partner, provide a situation in which a seronegativ
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