- Community‐based supplementary feeding for promoting the growth of children under five years of age in low and middle income countries
Cochrane Systematic Reviews, 13-Jun-2012
Supplementary feeding is defined as the provision of extra food to children or families beyond the normal ration of their home diets. The impact of food supplementation on child growth merits careful evaluation in view of the reliance of many states and n - Community‐level interventions for improving access to food in low‐ and middle‐income countries
Cochrane Systematic Reviews, 5-Aug-2020
After decades of decline since 2005, the global prevalence of undernourishment reverted and since 2015 has increased to levels seen in 2010 to 2011. The prevalence is highest in low- and middle-income countries (LMICs), especially Africa and Asia. Food in - Comparative effectiveness of continuation and maintenance treatments for persistent depressive disorder in adults
Cochrane Systematic Reviews, 20-May-2019
Persistent depressive disorder (PDD) is defined as a depressive disorder with a minimum illness duration of two years, including four diagnostic subgroups (dysthymia, chronic major depression, recurrent major depression with incomplete remission between e - Comparative efficacy of epidural, subarachnoid, and intracerebroventricular opioids in patients with pain due to cancer
Cochrane Systematic Reviews, 29-Oct-2015
Since the 1970s, when endogenous opioids and opioid receptors were first isolated in the central nervous system, attempts have been made to optimize opioid therapy by delivering the medication centrally rather than systemically. Although the vast majority - Comparison of a restrictive versus liberal red cell transfusion policy for patients with myelodysplasia, aplastic anaemia, and other congenital bone marrow failure disorders
Cochrane Systematic Reviews, 5-Oct-2015
Bone marrow failure disorders include a heterogenous group of disorders, of which myelodysplastic syndrome (MDS), forms the largest subgroup. MDS is predominantly a disease of the elderly, with many elderly people managed conservatively with regular allog - Comparison of a therapeutic‐only versus prophylactic platelet transfusion policy for people with congenital or acquired bone marrow failure disorders
Cochrane Systematic Reviews, 14-May-2018
Bone marrow disorders encompass a group of diseases characterised by reduced production of red cells, white cells, and platelets, or defects in their function, or both. The most common bone marrow disorder is myelodysplastic syndrome. Thrombocytopenia, a - Comparison of animal-derived surfactants for the prevention and treatment of respiratory distress syndrome in preterm infants
Cochrane Systematic Reviews, 14-Dec-2015
Animal-derived surfactants have been shown to have several advantages over the first generation synthetic surfactants and are the most commonly used surfactant preparations. The animal-derived surfactants in clinical use are minced or lavaged and modified - Comparison of antiepileptic drugs, no treatment, or placebo for children with benign epilepsy with centro temporal spikes
Cochrane Systematic Reviews, 26-Aug-2014
Benign Epilepsy with Centro Temporal Spikes (BECTS) is a common epilepsy syndrome with onset in childhood which almost always remits by adolescence. It is characterised by focal seizures associated with motor signs and somatosensory symptoms, at times pro - Comparison of different human papillomavirus (HPV) vaccine types and dose schedules for prevention of HPV‐related disease in females and males
Cochrane Systematic Reviews, 22-Nov-2019
Uptake of human papillomavirus (HPV) vaccine remains low in many countries, although the bivalent and quadrivalent HPV vaccines given as a three-dose schedule are effective in the prevention of precancerous lesions of the cervix in women. Simpler immunisa - Comparison of different platelet count thresholds to guide administration of prophylactic platelet transfusion for preventing bleeding in people with haematological disorders after myelosuppressive chemotherapy or stem cell transplantation
Cochrane Systematic Reviews, 18-Nov-2015
Platelet transfusions are used in modern clinical practice to prevent and treat bleeding in people who are thrombocytopenic due to bone marrow failure. Although considerable advances have been made in platelet transfusion therapy in the last 40 years, som - Comparison of different platelet transfusion thresholds prior to insertion of central lines in patients with thrombocytopenia
Cochrane Systematic Reviews, 2-Dec-2015
Patients with a low platelet count (thrombocytopenia) often require the insertion of central lines (central venous catheters (CVCs)). CVCs have a number of uses; these include: administration of chemotherapy; intensive monitoring and treatment of critical - Comparison of different protein concentrations of human milk fortifier for promoting growth and neurological development in preterm infants
Cochrane Systematic Reviews, 20-Nov-2020
Human milk alone may provide inadequate amounts of protein to meet the growth requirements of preterm infants because of restrictions in the amount of fluid they can tolerate. It has become common practice to feed preterm infants with breast milk fortifie - Comparison of different regimens of proton pump inhibitors for acute peptic ulcer bleeding
Cochrane Systematic Reviews, 11-Jun-2013
Treatment with proton pump inhibitors (PPIs) improves clinical outcomes in patients with peptic ulcer bleeding. However, the optimal dose and route of administration of PPIs remains controversial. - Comparison of first‐line chemotherapy including escalated BEACOPP versus chemotherapy including ABVD for people with early unfavourable or advanced stage Hodgkin lymphoma
Cochrane Systematic Reviews, 25-May-2017
There are two different international standards for the treatment of early unfavourable and advanced stage Hodgkin lymphoma (HL): chemotherapy with escalated BEACOPP (bleomycin/etoposide/doxorubicin/cyclophosphamide/vincristine/procarbazine/prednisone) re - Comparison of routes for achieving parenteral access with a focus on the management of patients with Ebola virus disease
Cochrane Systematic Reviews, 25-Feb-2015
Dehydration is an important cause of death in patients with Ebola virus disease (EVD). Parenteral fluids are often required in patients with fluid requirements in excess of their oral intake. The peripheral intravenous route is the most commonly used meth - Comparison of speech and language therapy techniques for speech problems in Parkinson's disease
Cochrane Systematic Reviews, 15-Aug-2012
Patients with Parkinson's disease commonly suffer from speech and voice difficulties such as impaired articulation and reduced loudness. Speech and language therapy (SLT) aims to improve the intelligibility of speech with behavioural treatment techniques - Comparisons of approaches to pelvic floor muscle training for urinary incontinence in women
Cochrane Systematic Reviews, 3-Nov-2011
Pelvic floor muscle training is the most commonly recommended physical therapy treatment for women with stress urinary incontinence. It is also sometimes recommended for mixed and, less commonly, urge urinary incontinence. The supervision and content of p - Competitions for smoking cessation
Cochrane Systematic Reviews, 20-Feb-2019
Competitions might encourage people to undertake and/or reinforce behaviour change, including smoking cessation. Competitions involve individuals or groups having the opportunity to win a prize following successful cessation, either through direct competi - Complement inhibitors for age-related macular degeneration
Cochrane Systematic Reviews, 9-Jan-2014
Given the relatively high prevalence of age-related macular degeneration (AMD) and the increased incidence of AMD as populations age, the results of trials of novel treatments are awaited with much anticipation. The complement cascade describes a series o - Complementary and alternative therapies for pain management in labour
Cochrane Systematic Reviews, 18-Oct-2006
Many women would like to avoid pharmacological or invasive methods of pain management in labour and this may contribute towards the popularity of complementary methods of pain management. This review examined currently available evidence supporting the us
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