- Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Assisted reproductive technologies (ART) including in vitro fertilisation (IVF) and intracytoplasmic sperm injection (ICSI), combine gametes to enhance the probability of fertilisation and pregnancy. Advanced sperm selection techniques are increasingly em - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Grade I or low-grade chondrosarcoma (LGCS) is a primary bone tumour with low malignant potential. Historically, it was treated by wide resection, since accurate pre-operative exclusion of more aggressive cancers can be challenging and under-treatment of a - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Penetrating abdominal trauma (PAT) is a common type of trauma leading to admission to hospital, which often progresses to septic complications. Antibiotics are commonly administered as prophylaxis prior to laparotomy for PAT. However, an earlier Cochrane - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Transitional care provides for the continuity of care as patients move between different stages and settings of care. Medication discrepancies arising at care transitions have been reported as prevalent and are linked with adverse drug events (ADEs) (e.g. - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Urolithiasis is a condition where crystalline mineral deposits (stones) form within the urinary tract. Urinary stones can be located in any part of the urinary tract. Affected children may present with abdominal pain, blood in the urine or signs of infect - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
In preterm newborns, the ductus arteriosus frequently fails to close and the infants require medical or surgical closure of the patent ductus arteriosus (PDA). A PDA can be treated surgically; or medically with one of two prostaglandin inhibitors, indomet - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Early childhood vaccination is an essential global public health practice that saves two to three million lives each year, but many children do not receive all the recommended vaccines. To achieve and maintain appropriate coverage rates, vaccination progr - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Respiratory support is a central component of the management of critically ill children. It can be delivered invasively via an endotracheal tube or non-invasively via face mask, nasal mask, nasal cannula or oxygen hood/tent. Invasive ventilation can be da - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Neuroblastoma is an embryonic tumour of childhood that originates in the neural crest. It is the second most common extracranial malignant solid tumour of childhood. - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Lung cancer is the most commonly diagnosed cancer and the leading cause of cancer death in both sexes worldwide. Approximately 50% of those diagnosed with lung cancer will have locally advanced or metastatic disease and will be treated in a palliative set - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Many patients with cancer experience moderate to severe pain that requires treatment with strong analgesics. Buprenorphine, fentanyl and morphine are examples of strong opioids used for the relief of cancer pain. Strong opioids are, however, not effective - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Transurethral resection of the prostate (TURP) is a well-established surgical method for treatment of men with lower urinary tract symptoms (LUTS) secondary to benign prostatic obstruction (BPO). This has traditionally been provided as monopolar TURP (MTU - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Chronic suppurative otitis media (CSOM), sometimes referred to as chronic otitis media (COM), is a chronic inflammation and often polymicrobial infection (involving more than one micro-organism) of the middle ear and mastoid cavity, characterised by ear d - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Chronic suppurative otitis media (CSOM), sometimes referred to as chronic otitis media (COM), is a chronic inflammation and infection of the middle ear and mastoid cavity, characterised by ear discharge (otorrhoea) through a perforated tympanic membrane. - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Chronic suppurative otitis media (CSOM), sometimes referred to as chronic otitis media (COM), is a chronic inflammation and infection of the middle ear and mastoid cavity, characterised by ear discharge (otorrhoea) through a perforated tympanic membrane. - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
This review is one in a series of Cochrane Reviews of interventions for shoulder disorders. - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Polycystic ovary syndrome (PCOS) is characterised by infrequent or absent ovulation, and high levels of androgens and insulin (hyperinsulinaemia). Hyperinsulinaemia occurs secondary to insulin resistance and is associated with an increased biochemical ris - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Cystic fibrosis (CF) is a multisystem disease and the importance of growth and nutrition has been well established, given its implications for lung function and overall survival. It has been established that intestinal dysbiosis (i.e. microbial imbalance) - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Persistent pulmonary hypertension of the newborn (PPHN) is a disease entity that describes a physiology in which there is persistence of increased pulmonary arterial pressure. PPHN is characterised by failure to adapt to a functional postnatal circulation - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Chronic rhinosinusitis frequently occurs in people with cystic fibrosis. Several medical interventions are available for treating chronic rhinosinusitis in people with cystic fibrosis; for example, different concentrations of nasal saline irrigations, top
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