- Colony stimulating factors (including erythropoietin, granulocyte colony stimulating factor and analogues) for stroke
Cochrane Systematic Reviews, 24-Jun-2013
Colony stimulating factors (CSFs), also called haematopoietic growth factors, regulate bone marrow production of circulating red and white cells, and platelets. Some CSFs also mobilise the release of bone marrow stem cells into the circulation. CSFs have - Colony‐stimulating factors for chemotherapy‐induced febrile neutropenia
Cochrane Systematic Reviews, 30-Oct-2014
Febrile neutropenia is a frequent adverse event experienced by people with cancer who are undergoing chemotherapy, and is a potentially life-threatening situation. The current treatment is supportive care plus antibiotics. Colony-stimulating factors (CSFs - Colony‐stimulating factors for prevention and treatment of infectious complications in patients with acute myelogenous leukemia
Cochrane Systematic Reviews, 13-Jun-2012
Acute myelogenous leukemia (AML) is a fatal bone marrow cancer. Colony-stimulating factors (CSFs) are frequently administered during and after chemotherapy to reduce complications. However, their safety with regard to disease-related outcomes and survival - Colony‐stimulating factors for prevention of myelosuppressive therapy‐induced febrile neutropenia in children with acute lymphoblastic leukaemia
Cochrane Systematic Reviews, 20-Jul-2005
Acute lymphoblastic leukaemia (ALL) is the most common cancer in childhood and febrile neutropenia is a potentially life-threatening side effect of its treatment. Current treatment consists of supportive care plus antibiotics. Clinical trials have attempt - Colorectal stents for the management of malignant colonic obstructions
Cochrane Systematic Reviews, 3-Oct-2011
Colorectal cancer is one of the most common cancer in the western world. Acute colonic obstruction is one of the common presentations of colon cancer. Emergency surgical decompression is the traditional treatment of choice but is associated with high morb - Combination antimicrobial susceptibility testing for acute exacerbations in chronic infection of Pseudomonas aeruginosa in cystic fibrosis
Cochrane Systematic Reviews, 15-May-2020
Antibiotic therapy for acute pulmonary exacerbations in people with cystic fibrosis is usually chosen based on the results of antimicrobial susceptibility testing of individual drugs. Combination antimicrobial susceptibility testing assesses the efficacy - Combination chemotherapy for primary treatment of high‐risk gestational trophoblastic tumour
Cochrane Systematic Reviews, 31-Jan-2013
This is an update of the original review that was published in The Cochrane Database of Systematic Reviews, 2009, Issue 2. Gestational trophoblastic neoplasia (GTN) are malignant disorders of the placenta that include invasive hydatidiform mole, choriocar - Combination chemotherapy versus single‐agent chemotherapy during preoperative chemoradiation for resectable rectal cancer
Cochrane Systematic Reviews, 21-Oct-2015
Colorectal cancer represents 10% of all cancers and is the third most common cause of death in women and men. Almost two-thirds of all bowel cancers are cancers of the colon and over one-third (34%) are cancers of the rectum, including the anus. Surgery i - Combination contraceptives: effects on weight
Cochrane Systematic Reviews, 15-Jan-2014
Weight gain is often considered a side effect of combination hormonal contraceptives, and many women and clinicians believe that an association exists. Concern about weight gain can limit the use of this highly effective method of contraception by deterri - Combination fixed‐dose beta agonist and steroid inhaler as required for adults or children with mild asthma
Cochrane Systematic Reviews, 4-May-2021
Asthma affects 350 million people worldwide including 45% to 70% with mild disease. Treatment is mainly with inhalers containing beta2-agonists, typically taken as required to relieve bronchospasm, and inhaled corticosteroids (ICS) as regular preventive t - Combination fluticasone and salmeterol versus fixed dose combination budesonide and formoterol for chronic asthma in adults and children
Cochrane Systematic Reviews, 6-Jul-2012
Long-acting beta-agonists are a common second line treatment in people with asthma inadequately controlled with inhaled corticosteroids. Single device inhalers combine a long-acting beta-agonist with an inhaled steroid delivering both drugs as a maintenan - Combination formoterol and budesonide as maintenance and reliever therapy versus combination inhaler maintenance for chronic asthma in adults and children
Cochrane Systematic Reviews, 16-Dec-2013
Asthma is characterised by chronic inflammation of the airways and recurrent exacerbations with wheezing, chest tightness and cough. Treatment with inhaled steroids and bronchodilators often results in good control of symptoms, prevention of further morbi - Combination formoterol and budesonide as maintenance and reliever therapy versus current best practice (including inhaled steroid maintenance), for chronic asthma in adults and children
Cochrane Systematic Reviews, 12-Jul-2016
Traditionally inhaled treatment for asthma has used separate preventer and reliever therapies. The combination of formoterol and budesonide in one inhaler has made possible a single inhaler for both prevention and relief of symptoms (single inhaler therap - Combination formoterol and inhaled steroid versus beta2‐agonist as relief medication for chronic asthma in adults and children
Cochrane Systematic Reviews, 21-Jan-2009
Formoterol has a fast onset of action and can therefore be used to relieve symptoms of asthma. A combination inhaler can deliver formoterol with different doses of inhaled corticosteroid; when used as a reliever both drugs will be delivered more frequentl - Combination inhaled corticosteroids and long‐acting beta2‐agonists for children and adults with bronchiectasis
Cochrane Systematic Reviews, 10-Jun-2014
Bronchiectasis is a major contributor to chronic respiratory morbidity and mortality worldwide. Wheeze and other asthma-like symptoms and bronchial hyperreactivity may occur in people with bronchiectasis. Physicians often use asthma treatments in patients - Combination inhaled steroid and long‐acting beta2‐agonist in addition to tiotropium versus tiotropium or combination alone for chronic obstructive pulmonary disease
Cochrane Systematic Reviews, 6-Jun-2016
The long-acting bronchodilator tiotropium and single-inhaler combination therapy of inhaled corticosteroids and long-acting beta2-agonists (ICS/LABA) are commonly used for maintenance treatment of patients with chronic obstructive pulmonary disease (COPD) - Combination inhaled steroid and long-acting beta2-agonist versus tiotropium for chronic obstructive pulmonary disease
Cochrane Systematic Reviews, 30-Apr-2013
Combination therapy (inhaled corticosteroids and long-acting beta2-agonists) and tiotropium are both used in the treatment of chronic obstructive pulmonary disease (COPD). There is uncertainty about the relative benefits and harms of these treatments. - Combination injectable contraceptives for contraception
Cochrane Systematic Reviews, 8-Oct-2008
Combination injectable contraceptives (CICs) provide a highly effective, reversible method of preventing pregnancy, and they do not require daily administration or use at the time of coitus. Although they are used in many countries, their acceptability co - Combination of the non‐invasive tests for the diagnosis of endometriosis
Cochrane Systematic Reviews, 13-Jul-2016
About 10% of women of reproductive age suffer from endometriosis, a costly chronic disease causing pelvic pain and subfertility. Laparoscopy is the gold standard diagnostic test for endometriosis, but is expensive and carries surgical risks. Currently, th - Combination of tocolytic agents for inhibiting preterm labour
Cochrane Systematic Reviews, 7-Jul-2014
Preterm birth represents the single largest cause of mortality and morbidity for newborns and a major cause of morbidity for pregnant women. Tocolytic agents include a wide range of drugs that can inhibit labour to prolong pregnancy. This may gain time to
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