- Clozapine for psychotic disorders in adults with intellectual disabilities
Cochrane Systematic Reviews, 23-Sep-2015
Psychosis is three times more common in people with an intellectual disability than in those without an intellectual disability. A low intelligence quotient (IQ) is a defining characteristic for intellectual disability and a risk factor for poor outcome i - Clozapine versus other atypical antipsychotics for schizophrenia
Cochrane Systematic Reviews, 9-Nov-2010
Clozapine is an atypical antipsychotic demonstrated to be superior in the treatment of refractory schizophrenia which causes fewer movement disorders. Clozapine, however, entails a significant risk of serious blood disorders such as agranulocytosis which - Clozapine versus typical neuroleptic medication for schizophrenia
Cochrane Systematic Reviews, 21-Jan-2009
Long-term drug treatment of schizophrenia with typical antipsychotic drugs has limitations: 25 to 33% of sufferers have illnesses that are treatment resistant. Clozapine is an antipsychotic drug, which is claimed to have superior efficacy and to cause few - Coasting (withholding gonadotrophins) for preventing ovarian hyperstimulation syndrome
Cochrane Systematic Reviews, 23-May-2017
Ovarian hyperstimulation syndrome (OHSS) is an iatrogenic and potentially life threatening condition resulting from excessive ovarian stimulation. Reported incidence of moderate to severe OHSS ranges from 0.6% to 5% of in vitro fertilization (IVF) cycles. - Co‐bedding in neonatal nursery for promoting growth and neurodevelopment in stable preterm twins
Cochrane Systematic Reviews, 14-Apr-2016
The increased birth rate of twins during recent decades and the improved prognosis of preterm infants have resulted in the need to explore measures that could optimize their growth and neurodevelopmental outcomes. It has been postulated that co-bedding si - Coblation versus other surgical techniques for tonsillectomy
Cochrane Systematic Reviews, 22-Aug-2017
Tonsillectomy is a very common operation and is performed using various surgical methods. Coblation is a popular method because it purportedly causes less pain than other surgical methods. However, the superiority of coblation is unproven. - Codeine versus placebo for chronic cough in children
Cochrane Systematic Reviews, 13-Jul-2016
Cough in children is a commonly experienced symptom that is associated with increased health service utilisation and burden to parents. The presence of chronic (equal to or more than four weeks) cough in children may indicate a serious underlying conditio - Coenzyme Q10 for heart failure
Cochrane Systematic Reviews, 3-Feb-2021
Coenzyme Q10, or ubiquinone, is a non-prescription nutritional supplement. It is a fat-soluble molecule that acts as an electron carrier in mitochondria, and as a coenzyme for mitochondrial enzymes. Coenzyme Q10 deficiency may be associated with a multitu - Coenzyme Q10 for Parkinson's disease
Cochrane Systematic Reviews, 16-Apr-2012
A number of preclinical studies in both in vitro and in vivo models of Parkinson's disease have demonstrated that coenzyme Q10 can protect the nigrostriatal dopaminergic system. Some clinical trials have looked at the neuroprotective effects of coenzyme Q - Co-enzyme Q10 supplementation for the primary prevention of cardiovascular disease
Cochrane Systematic Reviews, 2-Dec-2014
Cardiovascular disease (CVD) remains the number one cause of death and disability worldwide and public health interventions focus on modifiable risk factors, such as diet. Coenzyme Q10 (CoQ10) is an antioxidant that is naturally synthesised by the body an - Co‐formulated abacavir‐lamivudine‐zidovudine for initial treatment of HIV infection and AIDS
Cochrane Systematic Reviews, 28-Mar-2013
UNAIDS estimates that 34 million people are currently living with the human immunodeficiency virus (HIV) worldwide. Currently recommended regimens for initiating HIV treatment consist of either a non-nucleoside reverse transcriptase inhibitor (NNRTI) or r - Cognition-based interventions for healthy older people and people with mild cognitive impairment
Cochrane Systematic Reviews, 7-Dec-2010
Evidence from some, but not all non-randomised studies suggest the possibility that cognitive training may influence cognitive functioning in older people. Due to the differences among cognitive training interventions reported in the literature, giving a - Cognitive behaviour therapy for chronic fatigue syndrome in adults
Cochrane Systematic Reviews, 16-Jul-2008
Chronic fatigue syndrome (CFS) is a common, debilitating and serious health problem. Cognitive behaviour therapy (CBT) may help to alleviate the symptoms of CFS. - Cognitive behavioural interventions for sleep problems in adults aged 60+
Cochrane Systematic Reviews, 20-Jan-2003
The prevalence of sleep problems in adulthood increases with age. While not all sleep changes are pathological in later life, severe disturbances may lead to depression, cognitive impairments, deterioration of quality of life, significant stresses for car - Cognitive behavioural therapies for fibromyalgia
Cochrane Systematic Reviews, 10-Sep-2013
Fibromyalgia (FM) is a clinically well-defined chronic condition of unknown aetiology characterized by chronic widespread pain that often co-exists with sleep disturbances, cognitive dysfunction and fatigue. Patients often report high disability levels an - Cognitive behavioural therapy (brief versus standard duration) for schizophrenia
Cochrane Systematic Reviews, 21-Oct-2015
Cognitive behavioural therapy for people with schizophrenia is a psychotherapeutic approach that establishes links between thoughts, emotions and behaviours and challenges dysfunctional thoughts. There is some evidence to suggest that cognitive behavioura - Cognitive behavioural therapy (CBT) for adults and adolescents with asthma
Cochrane Systematic Reviews, 21-Sep-2016
People with asthma have a higher prevalence of anxiety and depression than the general population. This is associated with poorer asthma control, medication adherence, and health outcomes. Cognitive behavioural therapy (CBT) may be a way to improve the qu - Cognitive behavioural therapy (CBT), third‐wave CBT and interpersonal therapy (IPT) based interventions for preventing depression in children and adolescents
Cochrane Systematic Reviews, 9-Aug-2016
Depression is common in young people. It has a marked negative impact and is associated with self-harm and suicide. Preventing its onset would be an important advance in public health. This is an update of a Cochrane review that was last updated in 2011. - Cognitive behavioural therapy (group) for schizophrenia
Cochrane Systematic Reviews, 12-Jul-2022
Schizophrenia is a disabling psychotic disorder characterised by positive symptoms of delusions, hallucinations, disorganised speech and behaviour; and negative symptoms such as affective flattening and lack of motivation. Cognitive behavioural therapy (C - Cognitive behavioural therapy for anxiety disorders in children and adolescents
Cochrane Systematic Reviews, 18-Feb-2015
A new Cochrane Review entitled 'Cognitive behavioural therapy for anxiety disorders in children and adolescents' was published on 16 November 2020 which supersedes this publication.
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