- Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Plague is a severe disease associated with high mortality. Late diagnosis leads to advance stage of the disease with worse outcomes and higher risk of spread of the disease. A rapid diagnostic test (RDT) could help in establishing a prompt diagnosis of pl - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Depression is common in people with non-communicable diseases (NCDs) such as cardiovascular disease, diabetes, cancer, and chronic respiratory conditions. The co-existence of depression and NCDs may affect health behaviours, compliance with treatment, phy - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Human milk as compared to formula reduces morbidity in preterm infants but requires fortification to meet their nutritional needs and to reduce the risk of extrauterine growth failure. Standard fortification methods are not individualized to the infant an - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Abdominal aortic graft infections are a major complication following abdominal aortic aneurysm surgery, with high morbidity and mortality rates. They can be treated surgically or conservatively using medical management. The two most common surgical techni - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Pharmaceuticals make an important contribution to people's health. Medicines, however, are frequently not used appropriately. Improving the use of medicines can improve health outcomes and save resources. On the other hand, regulatory and educational poli - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Uptake of human papillomavirus (HPV) vaccine remains low in many countries, although the bivalent and quadrivalent HPV vaccines given as a three-dose schedule are effective in the prevention of precancerous lesions of the cervix in women. Simpler immunisa - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Multiple myeloma is a bone marrow-based hematological malignancy accounting for approximately two per cent of cancers. First-line treatment for transplant-ineligible individuals consists of multiple drug combinations of bortezomib (V), lenalidomide (R), o - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
GM-CSF (granulocyte macrophage colony-stimulating factor) is a growth factor that is used to supplement culture media in an effort to improve clinical outcomes for those undergoing assisted reproduction. It is worth noting that the use of GM-CSF-supplemen - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
This review is one in a series of Cochrane Reviews of interventions for shoulder disorders. - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Polycystic ovary syndrome (PCOS) is characterised by infrequent or absent ovulation, and high levels of androgens and insulin (hyperinsulinaemia). Hyperinsulinaemia occurs secondary to insulin resistance and is associated with an increased biochemical ris - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
This living systematic review is one of several Cochrane Reviews evaluating the medical management of patients with chronic rhinosinusitis. - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Shared decision-making is important in child and adolescent healthcare because there is growing international recognition of children and young people's rights to be included in decisions that affect them. In order for young people to participate effectiv - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is a common disorder in which the two main clinical features are pelvic pain and lower urinary tract symptoms. There are currently many approaches for its management, using both pharmacological an - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Adults spend a majority of their time outside the workplace being sedentary. Large amounts of sedentary behaviour increase the risk of type 2 diabetes, cardiovascular disease, and both all-cause and cardiovascular disease mortality. - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Subfertile women are highly motivated to try different adjunctive therapies to have a baby, and the widespread perception is that dietary supplements such as myo-inositol (MI) and D-chiro-insoitol (DCI) are associated with only benefit, and not with harm. - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Chronic kidney disease (CKD) is associated with high morbidity and death, which increases as CKD progresses to end-stage kidney disease (ESKD). There has been increasing interest in developing innovative, effective and cost-efficient methods to engage wit - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Sickle cell disease (SCD) is one of the commonest severe monogenic disorders in the world, due to the inheritance of two abnormal haemoglobin (beta-globin) genes. SCD can cause severe pain, significant end-organ damage, pulmonary complications, and premat - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Intrahepatic cholestasis of pregnancy is a pregnancy-specific liver disorder, possibly associated with an increased risk of severe fetal adverse events. Total serum bile acids (TSBA) concentration, alone or in combination with serum aminotransferases, hav - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Poor diet and insufficient physical activity are major risk factors for non-communicable diseases. Developing healthy diet and physical activity behaviors early in life is important as these behaviors track between childhood and adulthood. Parents and oth - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Hodgkin's lymphoma (HL) is a cancer of the lymphatic system, and involves the lymph nodes, spleen and other organs such as the liver, lung, bone or bone marrow, depending on the tumour stage. With cure rates of up to 90%, HL is one of the most curable can
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