- Ciliary neurotrophic factor (CNTF) for amyotrophic lateral sclerosis or motor neuron disease
Cochrane Systematic Reviews, 19-Jul-2004
Amyotrophic lateral sclerosis, also known as motor neuron disease, is a fatal neuromuscular disease characterized by progressive muscle weakness resulting in paralysis. It might be treated with ciliary neurotrophic factor. This is an updated review. An up - Cilostazol for intermittent claudication
Cochrane Systematic Reviews, 30-Jun-2021
Peripheral arterial disease (PAD) affects between 4% and 12% of people aged 55 to 70 years, and 20% of people over 70 years. A common complaint is intermittent claudication (exercise-induced lower limb pain relieved by rest). These patients have a three- - Cilostazol versus aspirin for secondary prevention of vascular events after stroke of arterial origin
Cochrane Systematic Reviews, 30-Aug-2011
Aspirin is widely used for secondary prevention after stroke. Cilostazol has shown promise as an alternative to aspirin in Asian people with stroke. - Cinnamon for diabetes mellitus
Cochrane Systematic Reviews, 12-Sep-2012
Diabetes mellitus is a chronic metabolic disorder that is associated with an increased risk of cardiovascular disease, retinopathy, nephropathy, neuropathy, sexual dysfunction and periodontal disease. Improvements in glycaemic control may help to reduce t - Circuit class therapy for improving mobility after stroke
Cochrane Systematic Reviews, 2-Jun-2017
Circuit class therapy (CCT) offers a supervised group forum for people after stroke to practise tasks, enabling increased practice time without increasing staffing. This is an update of the original review published in 2010. - Circulating antigen tests and urine reagent strips for diagnosis of active schistosomiasis in endemic areas
Cochrane Systematic Reviews, 11-Mar-2015
Point-of-care (POC) tests for diagnosing schistosomiasis include tests based on circulating antigen detection and urine reagent strip tests. If they had sufficient diagnostic accuracy they could replace conventional microscopy as they provide a quicker an - Circulatory volume expansion therapy for aneurysmal subarachnoid haemorrhage
Cochrane Systematic Reviews, 18-Oct-2004
Secondary ischaemia is a frequent complication after aneurysmal subarachnoid haemorrhage (SAH), and responsible for a substantial proportion of patients with poor outcome after SAH. The cause of secondary ischaemia is unknown, but hypovolaemia and fluid r - Circumcision devices versus standard surgical techniques in adolescent and adult male circumcisions
Cochrane Systematic Reviews, 31-Mar-2021
Medical circumcisions are among the most common surgical procedures performed in males. The usual indications are phimosis (inability to completely retract the foreskin and expose the glans due to a congenital or acquired constriction of the prepuce), par - Cisapride for Intestinal Constipation
Cochrane Systematic Reviews, 7-Dec-2010
Cisapride is a propulsive agent, withdrawn from most of the world's health institutes because of its recorded fatalities in addition to serious side effects such as severe arrhythmias. However it is widely available in third world countries and can be eas - Cisapride treatment for gastro‐oesophageal reflux in children
Cochrane Systematic Reviews, 14-Apr-2010
Gastro-oesophageal reflux (GOR) is common and usually self-limiting in infants. Cisapride, a pro-kinetic agent, was commonly prescribed until reports of possible serious adverse events were associated with its use. - Cisplatin versus carboplatin in combination with third‐generation drugs for advanced non‐small cell lung cancer
Cochrane Systematic Reviews, 13-Jan-2020
Lung cancer is the most commonly diagnosed cancer and the leading cause of cancer death in both sexes worldwide. Approximately 50% of those diagnosed with lung cancer will have locally advanced or metastatic disease and will be treated in a palliative set - Citalopram versus other anti-depressive agents for depression
Cochrane Systematic Reviews, 12-Jun-2012
Recent US and UK clinical practice guidelines recommend that second-generation antidepressants should be considered amongst the best first-line options when drug therapy is indicated for a depressive episode. Systematic reviews have already highlighted so - Citicoline for treating people with acute ischemic stroke
Cochrane Systematic Reviews, 29-Aug-2020
Stroke is one of the leading causes of long-lasting disability and mortality and its global burden has increased in the past two decades. Several therapies have been proposed for the recovery from, and treatment of, ischemic stroke. One of them is citicol - Citrate salts for preventing and treating calcium containing kidney stones in adults
Cochrane Systematic Reviews, 6-Oct-2015
Kidney stones affect people worldwide and have a high rate of recurrence even with treatment. Recurrences are particularly prevalent in people with low urinary citrate levels. These people have a higher incidence of calcium phosphate and calcium oxalate s - Cleavage‐stage versus blastocyst‐stage embryo transfer in assisted reproductive technology
Cochrane Systematic Reviews, 19-May-2022
Advances in embryo culture media have led to a shift in in vitro fertilisation (IVF) practice from cleavage-stage embryo transfer to blastocyst-stage embryo transfer. The rationale for blastocyst-stage transfer is to improve both uterine and embryonic syn - Client feedback in psychological therapy for children and adolescents with mental health problems
Cochrane Systematic Reviews, 20-Aug-2018
Childhood and adolescent mental health problems are a serious and growing concern worldwide. Research suggests that psychotherapy can have a significant and positive impact on children and adolescents with mental health problems, such as anxiety disorders - Clients’ perceptions and experiences of targeted digital communication accessible via mobile devices for reproductive, maternal, newborn, child, and adolescent health: a qualitative evidence synthesis
Cochrane Systematic Reviews, 14-Oct-2019
Governments and health systems are increasingly using mobile devices to communicate with patients and the public. Targeted digital client communication is when the health system transmits information to particular individuals or groups of people, based on - Clinical assessment for the detection of oral cavity cancer and potentially malignant disorders in apparently healthy adults
Cochrane Systematic Reviews, 10-Dec-2021
The early detection of oral cavity squamous cell carcinoma (OSCC) and oral potentially malignant disorders (OPMD), followed by appropriate treatment, may improve survival and reduce the risk for malignant transformation respectively. This is an update of - Clinical decision support systems for neonatal care
Cochrane Systematic Reviews, 20-Apr-2005
Clinical decision support systems (CDSS) are computer-based information systems used to integrate clinical and patient information to provide support for decision-making in patient care. They may be useful in aiding the diagnostic process, the generation - Clinical judgement by primary care physicians for the diagnosis of all‐cause dementia or cognitive impairment in symptomatic people
Cochrane Systematic Reviews, 16-Jun-2022
In primary care, general practitioners (GPs) unavoidably reach a clinical judgement about a patient as part of their encounter with patients, and so clinical judgement can be an important part of the diagnostic evaluation. Typically clinical decision maki
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