- Cleavage‐stage versus blastocyst‐stage embryo transfer in assisted reproductive technology
Cochrane Systematic Reviews, 19-May-2022
Advances in embryo culture media have led to a shift in in vitro fertilisation (IVF) practice from cleavage-stage embryo transfer to blastocyst-stage embryo transfer. The rationale for blastocyst-stage transfer is to improve both uterine and embryonic syn - Client feedback in psychological therapy for children and adolescents with mental health problems
Cochrane Systematic Reviews, 20-Aug-2018
Childhood and adolescent mental health problems are a serious and growing concern worldwide. Research suggests that psychotherapy can have a significant and positive impact on children and adolescents with mental health problems, such as anxiety disorders - Clients’ perceptions and experiences of targeted digital communication accessible via mobile devices for reproductive, maternal, newborn, child, and adolescent health: a qualitative evidence synthesis
Cochrane Systematic Reviews, 14-Oct-2019
Governments and health systems are increasingly using mobile devices to communicate with patients and the public. Targeted digital client communication is when the health system transmits information to particular individuals or groups of people, based on - Clinical assessment for the detection of oral cavity cancer and potentially malignant disorders in apparently healthy adults
Cochrane Systematic Reviews, 10-Dec-2021
The early detection of oral cavity squamous cell carcinoma (OSCC) and oral potentially malignant disorders (OPMD), followed by appropriate treatment, may improve survival and reduce the risk for malignant transformation respectively. This is an update of - Clinical decision support systems for neonatal care
Cochrane Systematic Reviews, 20-Apr-2005
Clinical decision support systems (CDSS) are computer-based information systems used to integrate clinical and patient information to provide support for decision-making in patient care. They may be useful in aiding the diagnostic process, the generation - Clinical judgement by primary care physicians for the diagnosis of all‐cause dementia or cognitive impairment in symptomatic people
Cochrane Systematic Reviews, 16-Jun-2022
In primary care, general practitioners (GPs) unavoidably reach a clinical judgement about a patient as part of their encounter with patients, and so clinical judgement can be an important part of the diagnostic evaluation. Typically clinical decision maki - Clinical pathways for chronic cough in children
Cochrane Systematic Reviews, 5-Sep-2014
Chronic cough (a cough lasting longer than four weeks) is a common problem internationally. Chronic cough has associated economic costs and is distressing to the child and to parents; ignoring cough may lead to delayed diagnosis and progression of serious - Clinical pathways: effects on professional practice, patient outcomes, length of stay and hospital costs
Cochrane Systematic Reviews, 15-Jun-2010
Clinical pathways are structured multidisciplinary care plans used by health services to detail essential steps in the care of patients with a specific clinical problem. They aim to link evidence to practice and optimise clinical outcomes whilst maximisin - Clinical symptoms and signs for the diagnosis of Mycoplasma pneumoniae in children and adolescents with community‐acquired pneumonia
Cochrane Systematic Reviews, 17-Oct-2012
Mycoplasma pneumoniae (M. pneumoniae) is a significant cause of community-acquired pneumonia in children and adolescents. Treatment with macrolide antibiotics is recommended. However, M. pneumoniae is difficult to diagnose based on clinical symptoms and s - Clinical symptoms, signs and tests for identification of impending and current water‐loss dehydration in older people
Cochrane Systematic Reviews, 30-Apr-2015
There is evidence that water-loss dehydration is common in older people and associated with many causes of morbidity and mortality. However, it is unclear what clinical symptoms, signs and tests may be used to identify early dehydration in older people, s - Clinically‐indicated replacement versus routine replacement of peripheral venous catheters
Cochrane Systematic Reviews, 23-Jan-2019
US Centers for Disease Control guidelines recommend replacement of peripheral intravenous catheters (PIVC) no more frequently than every 72 to 96 hours. Routine replacement is thought to reduce the risk of phlebitis and bloodstream infection. Catheter ins - Clinician‐targeted interventions to influence antibiotic prescribing behaviour for acute respiratory infections in primary care: an overview of systematic reviews
Cochrane Systematic Reviews, 7-Sep-2017
Antibiotic resistance is a worldwide health threat. Interventions that reduce antibiotic prescribing by clinicians are expected to reduce antibiotic resistance. Disparate interventions to change antibiotic prescribing behaviour for acute respiratory infec - Clobazam add‐on therapy for drug‐resistant epilepsy
Cochrane Systematic Reviews, 22-Oct-2019
Epilepsy affects approximately 1% of the population, with up to 30% of patients continuing to have seizures, despite antiepileptic drug treatment. Clobazam is a 1,5-benzodiazepine and is commonly used as an add-on treatment for drug-resistant epilepsy. Th - Clobazam monotherapy for focal or generalized seizures
Cochrane Systematic Reviews, 11-Jul-2018
This is an updated version of the original Cochrane Review published in Issue 10, 2014. There is a need to expand monotherapy options available to a clinician for the treatment of new focal or generalized seizures. A Cochrane systematic review for clobaza - Clofibrate in combination with phototherapy for unconjugated neonatal hyperbilirubinaemia
Cochrane Systematic Reviews, 12-Dec-2012
There are many pathological conditions leading to an elevated unconjugated bilirubin level (hyperbilirubinaemia) in neonates. Currently the standard therapies for unconjugated hyperbilirubinaemia include phototherapy and exchange transfusion. In addition - Clomiphene and other antioestrogens for ovulation induction in polycystic ovarian syndrome
Cochrane Systematic Reviews, 15-Dec-2016
Subfertility due to anovulation is a common problem in women. First-line oral treatment is with antioestrogens such as clomiphene citrate, but resistance may be apparent with clomiphene. Alternative and adjunctive treatments have been used including tamox - Clomiphene citrate for ovulation induction in women with oligo-amenorrhoea
Cochrane Systematic Reviews, 17-Jul-2008
The administration of clomiphene citrate is followed by an enhanced release of pituitary gonadotropins resulting in follicular recruitment. After the drug is stopped, there is continuing secretion of estradiol, selection of the dominant follicle and, in s - Clomiphene citrate for unexplained subfertility in women
Cochrane Systematic Reviews, 20-Jan-2010
The effectiveness of clomiphene citrate has been demonstrated in the treatment of subfertility associated with infrequent or irregular ovulation. The physiologic effects and clinical benefits in ovulatory women with unexplained subfertility are less clear - Clomiphene or tamoxifen for idiopathic oligo/asthenospermia
Cochrane Systematic Reviews, 17-Jul-2008
Oligo-astheno-teratospermia (sperm of low concentration, reduced motility and increased abnormal morphology) of unknown cause is common and the need for treatment is felt by patients and doctors alike. As a result, a variety of empirical, non-specific tre - Clonazepam add‐on therapy for drug‐resistant epilepsy
Cochrane Systematic Reviews, 20-Apr-2020
This is an updated version of the original Cochrane Review published in 2018, Issue 5.
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