- Circulating antigen tests and urine reagent strips for diagnosis of active schistosomiasis in endemic areas
Cochrane Systematic Reviews, 11-Mar-2015
Point-of-care (POC) tests for diagnosing schistosomiasis include tests based on circulating antigen detection and urine reagent strip tests. If they had sufficient diagnostic accuracy they could replace conventional microscopy as they provide a quicker an - Circulatory volume expansion therapy for aneurysmal subarachnoid haemorrhage
Cochrane Systematic Reviews, 18-Oct-2004
Secondary ischaemia is a frequent complication after aneurysmal subarachnoid haemorrhage (SAH), and responsible for a substantial proportion of patients with poor outcome after SAH. The cause of secondary ischaemia is unknown, but hypovolaemia and fluid r - Circumcision devices versus standard surgical techniques in adolescent and adult male circumcisions
Cochrane Systematic Reviews, 31-Mar-2021
Medical circumcisions are among the most common surgical procedures performed in males. The usual indications are phimosis (inability to completely retract the foreskin and expose the glans due to a congenital or acquired constriction of the prepuce), par - Cisapride for Intestinal Constipation
Cochrane Systematic Reviews, 7-Dec-2010
Cisapride is a propulsive agent, withdrawn from most of the world's health institutes because of its recorded fatalities in addition to serious side effects such as severe arrhythmias. However it is widely available in third world countries and can be eas - Cisapride treatment for gastro‐oesophageal reflux in children
Cochrane Systematic Reviews, 14-Apr-2010
Gastro-oesophageal reflux (GOR) is common and usually self-limiting in infants. Cisapride, a pro-kinetic agent, was commonly prescribed until reports of possible serious adverse events were associated with its use. - Cisplatin versus carboplatin in combination with third‐generation drugs for advanced non‐small cell lung cancer
Cochrane Systematic Reviews, 13-Jan-2020
Lung cancer is the most commonly diagnosed cancer and the leading cause of cancer death in both sexes worldwide. Approximately 50% of those diagnosed with lung cancer will have locally advanced or metastatic disease and will be treated in a palliative set - Citalopram versus other anti-depressive agents for depression
Cochrane Systematic Reviews, 12-Jun-2012
Recent US and UK clinical practice guidelines recommend that second-generation antidepressants should be considered amongst the best first-line options when drug therapy is indicated for a depressive episode. Systematic reviews have already highlighted so - Citicoline for treating people with acute ischemic stroke
Cochrane Systematic Reviews, 29-Aug-2020
Stroke is one of the leading causes of long-lasting disability and mortality and its global burden has increased in the past two decades. Several therapies have been proposed for the recovery from, and treatment of, ischemic stroke. One of them is citicol - Citrate salts for preventing and treating calcium containing kidney stones in adults
Cochrane Systematic Reviews, 6-Oct-2015
Kidney stones affect people worldwide and have a high rate of recurrence even with treatment. Recurrences are particularly prevalent in people with low urinary citrate levels. These people have a higher incidence of calcium phosphate and calcium oxalate s - Cleavage‐stage versus blastocyst‐stage embryo transfer in assisted reproductive technology
Cochrane Systematic Reviews, 19-May-2022
Advances in embryo culture media have led to a shift in in vitro fertilisation (IVF) practice from cleavage-stage embryo transfer to blastocyst-stage embryo transfer. The rationale for blastocyst-stage transfer is to improve both uterine and embryonic syn - Client feedback in psychological therapy for children and adolescents with mental health problems
Cochrane Systematic Reviews, 20-Aug-2018
Childhood and adolescent mental health problems are a serious and growing concern worldwide. Research suggests that psychotherapy can have a significant and positive impact on children and adolescents with mental health problems, such as anxiety disorders - Clients’ perceptions and experiences of targeted digital communication accessible via mobile devices for reproductive, maternal, newborn, child, and adolescent health: a qualitative evidence synthesis
Cochrane Systematic Reviews, 14-Oct-2019
Governments and health systems are increasingly using mobile devices to communicate with patients and the public. Targeted digital client communication is when the health system transmits information to particular individuals or groups of people, based on - Clinical assessment for the detection of oral cavity cancer and potentially malignant disorders in apparently healthy adults
Cochrane Systematic Reviews, 10-Dec-2021
The early detection of oral cavity squamous cell carcinoma (OSCC) and oral potentially malignant disorders (OPMD), followed by appropriate treatment, may improve survival and reduce the risk for malignant transformation respectively. This is an update of - Clinical decision support systems for neonatal care
Cochrane Systematic Reviews, 20-Apr-2005
Clinical decision support systems (CDSS) are computer-based information systems used to integrate clinical and patient information to provide support for decision-making in patient care. They may be useful in aiding the diagnostic process, the generation - Clinical pathways for chronic cough in children
Cochrane Systematic Reviews, 5-Sep-2014
Chronic cough (a cough lasting longer than four weeks) is a common problem internationally. Chronic cough has associated economic costs and is distressing to the child and to parents; ignoring cough may lead to delayed diagnosis and progression of serious - Clinical pathways: effects on professional practice, patient outcomes, length of stay and hospital costs
Cochrane Systematic Reviews, 15-Jun-2010
Clinical pathways are structured multidisciplinary care plans used by health services to detail essential steps in the care of patients with a specific clinical problem. They aim to link evidence to practice and optimise clinical outcomes whilst maximisin - Clinical symptoms and signs for the diagnosis of Mycoplasma pneumoniae in children and adolescents with community‐acquired pneumonia
Cochrane Systematic Reviews, 17-Oct-2012
Mycoplasma pneumoniae (M. pneumoniae) is a significant cause of community-acquired pneumonia in children and adolescents. Treatment with macrolide antibiotics is recommended. However, M. pneumoniae is difficult to diagnose based on clinical symptoms and s - Clinical symptoms, signs and tests for identification of impending and current water‐loss dehydration in older people
Cochrane Systematic Reviews, 30-Apr-2015
There is evidence that water-loss dehydration is common in older people and associated with many causes of morbidity and mortality. However, it is unclear what clinical symptoms, signs and tests may be used to identify early dehydration in older people, s - Clinically‐indicated replacement versus routine replacement of peripheral venous catheters
Cochrane Systematic Reviews, 23-Jan-2019
US Centers for Disease Control guidelines recommend replacement of peripheral intravenous catheters (PIVC) no more frequently than every 72 to 96 hours. Routine replacement is thought to reduce the risk of phlebitis and bloodstream infection. Catheter ins - Clinician‐targeted interventions to influence antibiotic prescribing behaviour for acute respiratory infections in primary care: an overview of systematic reviews
Cochrane Systematic Reviews, 7-Sep-2017
Antibiotic resistance is a worldwide health threat. Interventions that reduce antibiotic prescribing by clinicians are expected to reduce antibiotic resistance. Disparate interventions to change antibiotic prescribing behaviour for acute respiratory infec
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