- Chronotherapy versus conventional statins therapy for the treatment of hyperlipidaemia
Cochrane Systematic Reviews, 26-Nov-2016
Elevated levels of total cholesterol and low-density lipoprotein play an important role in the development of atheromas and, therefore, in cardiovascular diseases. Cholesterol biosynthesis follows a circadian rhythm and is principally produced at night (b - Chuanxiong preparations for preventing stroke
Cochrane Systematic Reviews, 3-Jun-2016
Stroke is a major healthcare problem and is one of the leading causes of death and serious long-term disability. Prevention of stroke is considered an important strategy. Chuanxiong is traditionally used in China in the treatment and prevention of stroke. - Chuanxiong-type preparations for acute ischemic stroke
Cochrane Systematic Reviews, 23-Jul-2008
Stroke, 88% of which are ischemic, is a common cause of death and disability all over the world. Chuanxiong has been reported to be beneficial in treating stroke. However, the strength of evidence to support its use is unclear. - Ciclesonide versus other inhaled corticosteroids for chronic asthma in children
Cochrane Systematic Reviews, 21-Dec-2012
Inhaled corticosteroids (ICS) are the cornerstone of asthma maintenance treatment in children. Particularly among parents, there is concern about the safety of ICS as studies in children have shown reduced growth. Small-particle-size ICS targeting the sma - Ciclesonide versus other inhaled steroids for chronic asthma in children and adults
Cochrane Systematic Reviews, 23-Apr-2008
Inhaled corticosteroids (ICS) are an integral part of asthma management, and act as an anti-inflammatory agent in the airways of the lung. These agents confer both significant benefit in terms of symptom management and improvement in lung function, but ma - Ciclesonide versus placebo for chronic asthma in adults and children
Cochrane Systematic Reviews, 23-Apr-2008
Inhaled corticosteroids are an integral part of asthma management, and act as an anti-inflammatory agent in the airways of the lung. These agents confer significant benefit in terms of symptom management and improvement in lung function, but may also caus - Ciliary neurotrophic factor (CNTF) for amyotrophic lateral sclerosis or motor neuron disease
Cochrane Systematic Reviews, 19-Jul-2004
Amyotrophic lateral sclerosis, also known as motor neuron disease, is a fatal neuromuscular disease characterized by progressive muscle weakness resulting in paralysis. It might be treated with ciliary neurotrophic factor. This is an updated review. An up - Cilostazol for intermittent claudication
Cochrane Systematic Reviews, 30-Jun-2021
Peripheral arterial disease (PAD) affects between 4% and 12% of people aged 55 to 70 years, and 20% of people over 70 years. A common complaint is intermittent claudication (exercise-induced lower limb pain relieved by rest). These patients have a three- - Cilostazol versus aspirin for secondary prevention of vascular events after stroke of arterial origin
Cochrane Systematic Reviews, 30-Aug-2011
Aspirin is widely used for secondary prevention after stroke. Cilostazol has shown promise as an alternative to aspirin in Asian people with stroke. - Cinnamon for diabetes mellitus
Cochrane Systematic Reviews, 12-Dec-2013
Diabetes mellitus is a chronic metabolic disorder that is associated with an increased risk of cardiovascular disease, retinopathy, nephropathy, neuropathy, sexual dysfunction and periodontal disease. Improvements in glycaemic control may help to reduce t - Circuit class therapy for improving mobility after stroke
Cochrane Systematic Reviews, 2-Jun-2017
Circuit class therapy (CCT) offers a supervised group forum for people after stroke to practise tasks, enabling increased practice time without increasing staffing. This is an update of the original review published in 2010. - Circulating antigen tests and urine reagent strips for diagnosis of active schistosomiasis in endemic areas
Cochrane Systematic Reviews, 11-Mar-2015
Point-of-care (POC) tests for diagnosing schistosomiasis include tests based on circulating antigen detection and urine reagent strip tests. If they had sufficient diagnostic accuracy they could replace conventional microscopy as they provide a quicker an - Circulatory volume expansion therapy for aneurysmal subarachnoid haemorrhage
Cochrane Systematic Reviews, 18-Oct-2004
Secondary ischaemia is a frequent complication after aneurysmal subarachnoid haemorrhage (SAH), and responsible for a substantial proportion of patients with poor outcome after SAH. The cause of secondary ischaemia is unknown, but hypovolaemia and fluid r - Circumcision devices versus standard surgical techniques in adolescent and adult male circumcisions
Cochrane Systematic Reviews, 31-Mar-2021
Medical circumcisions are among the most common surgical procedures performed in males. The usual indications are phimosis (inability to completely retract the foreskin and expose the glans due to a congenital or acquired constriction of the prepuce), par - Cisapride for Intestinal Constipation
Cochrane Systematic Reviews, 7-Dec-2010
Cisapride is a propulsive agent, withdrawn from most of the world's health institutes because of its recorded fatalities in addition to serious side effects such as severe arrhythmias. However it is widely available in third world countries and can be eas - Cisapride treatment for gastro‐oesophageal reflux in children
Cochrane Systematic Reviews, 14-Apr-2010
Gastro-oesophageal reflux (GOR) is common and usually self-limiting in infants. Cisapride, a pro-kinetic agent, was commonly prescribed until reports of possible serious adverse events were associated with its use. - Cisplatin versus carboplatin in combination with third‐generation drugs for advanced non‐small cell lung cancer
Cochrane Systematic Reviews, 13-Jan-2020
Lung cancer is the most commonly diagnosed cancer and the leading cause of cancer death in both sexes worldwide. Approximately 50% of those diagnosed with lung cancer will have locally advanced or metastatic disease and will be treated in a palliative set - Citalopram versus other anti-depressive agents for depression
Cochrane Systematic Reviews, 12-Jun-2012
Recent US and UK clinical practice guidelines recommend that second-generation antidepressants should be considered amongst the best first-line options when drug therapy is indicated for a depressive episode. Systematic reviews have already highlighted so - Citicoline for treating people with acute ischemic stroke
Cochrane Systematic Reviews, 29-Aug-2020
Stroke is one of the leading causes of long-lasting disability and mortality and its global burden has increased in the past two decades. Several therapies have been proposed for the recovery from, and treatment of, ischemic stroke. One of them is citicol - Citrate salts for preventing and treating calcium containing kidney stones in adults
Cochrane Systematic Reviews, 6-Oct-2015
Kidney stones affect people worldwide and have a high rate of recurrence even with treatment. Recurrences are particularly prevalent in people with low urinary citrate levels. These people have a higher incidence of calcium phosphate and calcium oxalate s
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