- Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Crohn's disease (CD) is a chronic relapsing inflammatory condition and maintenance of remission is a major issue as many patients fail to achieve remission with medical management and require surgical interventions. Purine analogues such as azathioprine ( - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Epilepsy is a serious brain disorder characterized by recurrent unprovoked seizures. Approximately two-thirds of seizures can be controlled with antiepileptic medications (Kwan 2000). For some of the others, surgery can completely eliminate or significant - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Accumulating evidence suggests an association between prenatal exposure to antiepileptic drugs (AEDs) and increased risk of both physical anomalies and neurodevelopmental impairment. Neurodevelopmental impairment is characterised by either a specific defi - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Initial resuscitation with air is well tolerated by most infants born at term. However, the optimal fractional inspired oxygen concentration (FiO2 - proportion of the breathed air that is oxygen) targeted to oxygen saturation (SpO2 - an estimate of the am - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Epithelial ovarian cancer (EOC) is often diagnosed at an advanced stage, requiring primary cytoreductive surgery and combination chemotherapy for its first-line management. Currently, the recommended standard first-line chemotherapy is platinum-based, usu - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
This is an updated version of the original Cochrane review published in 2015, Issue 10. - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Telerehabilitation, an emerging method, extends rehabilitative care beyond the hospital, and facilitates multifaceted, often psychotherapeutic approaches to modern management of patients using telecommunication technology at home or in the community. Alth - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Psoriasis is a chronic inflammatory skin condition that can markedly reduce life quality. Several systemic therapies exist for moderate to severe psoriasis, including oral fumaric acid esters (FAE). These contain dimethyl fumarate (DMF), the main active i - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Group A streptococcus (GAS) accounts for 20% to 40% of cases of pharyngitis in children; the remaining cases are caused by viruses. Compared with throat culture, rapid antigen detection tests (RADTs) offer diagnosis at the point of care (within five to 10 - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Food allergy is an abnormal immunological response following exposure (usually ingestion) to a food. Elimination of the allergen is the principle treatment for food allergy, including allergy to fruit. Accidental ingestion of allergenic foods can result i - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Chlorpromazine is an aliphatic phenothiazine, which is one of the widely-used typical antipsychotic drugs. Chlorpromazine is reliable for its efficacy and one of the most tested first generation antipsychotic drugs. It has been used as a ‘gold standard’ t - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
¹8F-FDFG uptake by brain tissue as measured by positron emission tomography (PET) is a well-established method for assessment of brain function in people with dementia. Certain findings on brain PET scans can potentially predict the decline of mild cognit - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Dementia with Lewy bodies (DLB) is a common cause of neurodegenerative dementia of old age. Its accurate recognition can be important in clinical management and is essential for the development of disease-modifying treatments. The current clinical diagnos - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Bronchiolitis is an acute inflammatory illness of the bronchioles common among infants and young children. It is often caused by the respiratory syncytial virus (RSV). Management of bronchiolitis varies between clinicians, reflecting the lack of evidence - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Periodontal disease and dental caries are highly prevalent oral diseases that can lead to pain and discomfort, oral hygiene and aesthetic problems, and eventually tooth loss, all of which can be costly to treat and are a burden to healthcare systems. Tric - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
People with dementia living in the community, that is in their own homes, are often not engaged in meaningful activities. Activities tailored to their individual interests and preferences might be one approach to improve quality of life and reduce challen - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Cataract is a leading cause of blindness worldwide. Cataract surgery is commonly performed but can result in postoperative inflammation of the eye. Inadequately controlled inflammation increases the risk of complications. Non-steroidal anti-inflammatory d - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Thalassaemia is a genetic disorder of the haemoglobin protein in red blood cells. It has been historically classified into thalassaemia minor, intermedia and major, depending on the genetic defect and severity of the disease. The clinical presentation of - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Please see Appendix 4 for a glossary of terms. - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Micronutrient deficiencies are widespread and compound the effects of HIV disease in children, especially in poor communities. Micronutrient supplements may be effective and safe in reducing the burden of HIV disease. This review is an update of an earlie
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