- Chloral hydrate as a sedating agent for neurodiagnostic procedures in children
Cochrane Systematic Reviews, 16-Aug-2021
This is an updated version of a Cochrane Review published in 2017. - Chlorambucil for patients with primary biliary cirrhosis
Cochrane Systematic Reviews, 16-Aug-2012
Chlorambucil has been used for patients with primary biliary cirrhosis as it possesses immunosuppressive properties. But it is unknown whether it benefits or harms these patients. - Chlorhexidine bathing of the critically ill for the prevention of hospital‐acquired infection
Cochrane Systematic Reviews, 30-Aug-2019
Hospital-acquired infection is a frequent adverse event in patient care; it can lead to longer stays in the intensive care unit (ICU), additional medical complications, permanent disability or death. Whilst all hospital-based patients are susceptible to i - Chlorhexidine mouthrinse as an adjunctive treatment for gingival health
Cochrane Systematic Reviews, 31-Mar-2017
Dental plaque associated gingivitis is a reversible inflammatory condition caused by accumulation and persistence of microbial biofilms (dental plaque) on the teeth. It is characterised by redness and swelling of the gingivae (gums) and a tendency for the - Chlorhexidine skin or cord care for prevention of mortality and infections in neonates
Cochrane Systematic Reviews, 9-Feb-2015
Affordable, feasible and efficacious interventions to reduce neonatal infections and improve neonatal survival are needed. Chlorhexidine, a broad spectrum topical antiseptic agent, is active against aerobic and anaerobic organisms and reduces neonatal bac - Chlorhexidine treatment for the prevention of dental caries in children and adolescents
Cochrane Systematic Reviews, 8-Apr-2015
Dental caries (tooth decay) is a common disease that is preventable by reducing the dietary intake of free sugars and using topical sodium fluoride products. An antibacterial agent known as chlorhexidine may also help prevent caries. A number of over-the- - Chloroquine as a steroid sparing agent for asthma
Cochrane Systematic Reviews, 20-Oct-2003
For the majority of chronic asthmatics, symptoms are best controlled using inhaled steroids, but for a small group of asthma sufferers, symptoms cannot be controlled using inhaled steroids and instead continuous use of high dosage oral steroids (corticost - Chloroquine or amodiaquine combined with sulfadoxine‐pyrimethamine for treating uncomplicated malaria
Cochrane Systematic Reviews, 19-Oct-2005
Chloroquine (CQ), amodiaquine (AQ), and sulfadoxine-pyrimethamine (SP) are inexpensive drugs, but treatment failure is a problem. Combination therapy may reduce treatment failure. CQ or AQ plus SP are affordable options of combination treatment, but there - Chloroquine or hydroxychloroquine for prevention and treatment of COVID‐19
Cochrane Systematic Reviews, 12-Feb-2021
The coronavirus disease 2019 (COVID-19) pandemic has resulted in substantial mortality. Some specialists proposed chloroquine (CQ) and hydroxychloroquine (HCQ) for treating or preventing the disease. The efficacy and safety of these drugs have been assess - Chlorproguanil‐dapsone for treating uncomplicated malaria
Cochrane Systematic Reviews, 18-Oct-2004
Using a pilot system we have categorised this review as: Historical question - no update intended. (Please see "Published notes" section of the review for more details). - Chlorpromazine dose for people with schizophrenia
Cochrane Systematic Reviews, 13-Apr-2017
The World Health Organization (WHO) Model Lists of Essential Medicines lists chlorpromazine as one of its five medicines used in psychotic disorders. - Chlorpromazine for psychosis induced aggression or agitation
Cochrane Systematic Reviews, 9-Nov-2010
Agitated or violent behaviour constitutes 10% of all emergency psychiatric treatment. Some guidelines do not recommend the use of chlorpromazine for rapid tranquillisation but it is still often used for this purpose. - Chlorpromazine versus atypical antipsychotic drugs for schizophrenia
Cochrane Systematic Reviews, 5-Apr-2016
Chlorpromazine is an aliphatic phenothiazine, which is one of the widely-used typical antipsychotic drugs. Chlorpromazine is reliable for its efficacy and one of the most tested first generation antipsychotic drugs. It has been used as a ‘gold standard’ t - Chlorpromazine versus clotiapine for schizophrenia
Cochrane Systematic Reviews, 7-Apr-2017
Schizophrenia is a chronic, disabling and severe mental disorder, characterised by disturbance in perception, thought, language, affect and motor behaviour. Chlorpromazine and clotiapine are among antipsychotic drugs used for the treatment of people with - Chlorpromazine versus metiapine for schizophrenia
Cochrane Systematic Reviews, 25-Mar-2017
Chlorpromazine, a widely available and inexpensive antipsychotic drug, is considered the benchmark treatment for schizophrenia worldwide. Metiapine, a dibenzothiazepine derivative, has been reported to have potent antipsychotic characteristics. However, n - Chlorpromazine versus penfluridol for schizophrenia
Cochrane Systematic Reviews, 23-Sep-2017
The efficacy of chlorpromazine, a benchmark antipsychotic, has not been fully assessed in direct comparison with different individual antipsychotics. Penfluridol is another old antipsychotic with a long half-life so one oral dose may last up to one week. - Chlorpromazine versus piperacetazine for schizophrenia
Cochrane Systematic Reviews, 31-Oct-2018
Schizophrenia is a severe mental disorder with a prevalence of about 1% among the general population. It is listed among the top 10 causes of disability-adjusted life years (DALYs) worldwide. Antipsychotics are the mainstay treatment. Piperacetazine has b - Chlorpromazine versus placebo for schizophrenia
Cochrane Systematic Reviews, 2-Nov-2015
Chlorpromazine, formulated in the 1950s, remains a benchmark treatment for people with schizophrenia. - Chlorpromazine versus reserpine for schizophrenia
Cochrane Systematic Reviews, 28-Apr-2016
In the 1940s reserpine, refined from a plant extract that had been used for centuries, began to be used as a treatment for people with mental disorders and was one of the very first antipsychotic drugs. Its irreversible pharmacological potency and adverse - Cholecystectomy deferral in patients with endoscopic sphincterotomy
Cochrane Systematic Reviews, 17-Oct-2007
Cholecystectomy is not required in up to 64% of patients who adopt a wait-and-see policy after endoscopic clearance of common bile duct stones. Although reports of retrospective cohort series have shown a higher mortality among patients who defer cholecys
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