- Chlorhexidine mouthrinse as an adjunctive treatment for gingival health
Cochrane Systematic Reviews, 31-Mar-2017
Dental plaque associated gingivitis is a reversible inflammatory condition caused by accumulation and persistence of microbial biofilms (dental plaque) on the teeth. It is characterised by redness and swelling of the gingivae (gums) and a tendency for the - Chlorhexidine skin or cord care for prevention of mortality and infections in neonates
Cochrane Systematic Reviews, 9-Feb-2015
Affordable, feasible and efficacious interventions to reduce neonatal infections and improve neonatal survival are needed. Chlorhexidine, a broad spectrum topical antiseptic agent, is active against aerobic and anaerobic organisms and reduces neonatal bac - Chlorhexidine treatment for the prevention of dental caries in children and adolescents
Cochrane Systematic Reviews, 8-Apr-2015
Dental caries (tooth decay) is a common disease that is preventable by reducing the dietary intake of free sugars and using topical sodium fluoride products. An antibacterial agent known as chlorhexidine may also help prevent caries. A number of over-the- - Chloroquine as a steroid sparing agent for asthma
Cochrane Systematic Reviews, 10-Mar-2011
For the majority of chronic asthmatics, symptoms are best controlled using inhaled steroids, but for a small group of asthma sufferers, symptoms cannot be controlled using inhaled steroids and instead continuous use of high dosage oral steroids (corticost - Chloroquine or amodiaquine combined with sulfadoxine‐pyrimethamine for treating uncomplicated malaria
Cochrane Systematic Reviews, 12-Nov-2008
Chloroquine (CQ), amodiaquine (AQ), and sulfadoxine-pyrimethamine (SP) are inexpensive drugs, but treatment failure is a problem. Combination therapy may reduce treatment failure. CQ or AQ plus SP are affordable options of combination treatment, but there - Chloroquine or hydroxychloroquine for prevention and treatment of COVID‐19
Cochrane Systematic Reviews,
The coronavirus disease 2019 (COVID-19) pandemic has resulted in substantial mortality. Some specialists proposed chloroquine (CQ) and hydroxychloroquine (HCQ) for treating or preventing the disease. The efficacy and safety of these drugs have been assess - Chlorproguanil‐dapsone for treating uncomplicated malaria
Cochrane Systematic Reviews, 17-Jan-2012
Using a pilot system we have categorised this review as: Historical question - no update intended. (Please see "Published notes" section of the review for more details). - Chlorpromazine dose for people with schizophrenia
Cochrane Systematic Reviews, 9-Mar-2017
The World Health Organization (WHO) Model Lists of Essential Medicines lists chlorpromazine as one of its five medicines used in psychotic disorders. - Chlorpromazine for psychosis induced aggression or agitation
Cochrane Systematic Reviews, 9-Nov-2010
Agitated or violent behaviour constitutes 10% of all emergency psychiatric treatment. Some guidelines do not recommend the use of chlorpromazine for rapid tranquillisation but it is still often used for this purpose. - Chlorpromazine versus atypical antipsychotic drugs for schizophrenia
Cochrane Systematic Reviews, 4-Apr-2016
Chlorpromazine is an aliphatic phenothiazine, which is one of the widely-used typical antipsychotic drugs. Chlorpromazine is reliable for its efficacy and one of the most tested first generation antipsychotic drugs. It has been used as a ‘gold standard’ t - Chlorpromazine versus clotiapine for schizophrenia
Cochrane Systematic Reviews, 7-Apr-2017
Schizophrenia is a chronic, disabling and severe mental disorder, characterised by disturbance in perception, thought, language, affect and motor behaviour. Chlorpromazine and clotiapine are among antipsychotic drugs used for the treatment of people with - Chlorpromazine versus metiapine for schizophrenia
Cochrane Systematic Reviews, 25-Mar-2017
Chlorpromazine, a widely available and inexpensive antipsychotic drug, is considered the benchmark treatment for schizophrenia worldwide. Metiapine, a dibenzothiazepine derivative, has been reported to have potent antipsychotic characteristics. However, n - Chlorpromazine versus penfluridol for schizophrenia
Cochrane Systematic Reviews, 19-Sep-2017
The efficacy of chlorpromazine, a benchmark antipsychotic, has not been fully assessed in direct comparison with different individual antipsychotics. Penfluridol is another old antipsychotic with a long half-life so one oral dose may last up to one week. - Chlorpromazine versus piperacetazine for schizophrenia
Cochrane Systematic Reviews, 29-Oct-2018
Schizophrenia is a severe mental disorder with a prevalence of about 1% among the general population. It is listed among the top 10 causes of disability-adjusted life years (DALYs) worldwide. Antipsychotics are the mainstay treatment. Piperacetazine has b - Chlorpromazine versus placebo for schizophrenia
Cochrane Systematic Reviews, 2-Nov-2015
Chlorpromazine, formulated in the 1950s, remains a benchmark treatment for people with schizophrenia. - Chlorpromazine versus reserpine for schizophrenia
Cochrane Systematic Reviews, 28-Apr-2016
In the 1940s reserpine, refined from a plant extract that had been used for centuries, began to be used as a treatment for people with mental disorders and was one of the very first antipsychotic drugs. Its irreversible pharmacological potency and adverse - Choice of instruments for assisted vaginal delivery
Cochrane Systematic Reviews, 5-Oct-2010
Instrumental or assisted vaginal birth is commonly used to expedite birth for the benefit of either mother or baby or both. It is sometimes associated with significant complications for both mother and baby. The choice of instrument may be influenced by c - Cholecystectomy deferral in patients with endoscopic sphincterotomy
Cochrane Systematic Reviews, 23-Sep-2008
Cholecystectomy is not required in up to 64% of patients who adopt a wait-and-see policy after endoscopic clearance of common bile duct stones. Although reports of retrospective cohort series have shown a higher mortality among patients who defer cholecys - Cholecystectomy for gallbladder polyp
Cochrane Systematic Reviews, 11-Nov-2008
The management of gallbladder polyps is controversial. Cholecystectomy has been recommended for gallbladder polyps larger than 10 mm because of the association with gallbladder cancer. Cholecystectomy has also been suggested for gallbladder polyps smaller - Cholecystectomy for patients with silent gallstones
Cochrane Systematic Reviews, 11-Nov-2008
Cholecystectomy is currently advised only for patients with symptomatic gallstones. However, about 4% of patients with asymptomatic gallstones develop symptoms including cholecystitis, obstructive jaundice, pancreatitis, and gallbladder cancer.
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