- Chemotherapy versus best supportive care for extensive small cell lung cancer
Cochrane Systematic Reviews, 22-Nov-2013
Combination chemotherapy has been the mainstay of treatment for extensive stage small celI lung cancer (SCLC) over the last 30 years, even though it only gives a short prolongation in median survival time. The main goal for these patients should be pallia - Chemotherapy wafers for high grade glioma
Cochrane Systematic Reviews, 16-Mar-2011
Standard treatment for high grade glioma (HGG) usually entails surgery (either biopsy or resection) followed by radiotherapy plus or minus temozolomide. Implanting wafers impregnated with chemotherapy agents into the resection cavity represents a novel me - Chemotherapy with cetuximab versus chemotherapy alone for chemotherapy‐naive advanced non‐small cell lung cancer
Cochrane Systematic Reviews, 17-Nov-2014
In advanced non-small cell lung cancer (NSCLC), the effectiveness of standard cytotoxic chemotherapy seems to have reached a 'plateau', and there is a continuous need for new treatments to further improve the prognosis. Cetuximab is a monoclonal antibody - Chemotherapy, radiotherapy and combined modality for Hodgkin's disease, with emphasis on second cancer risk
Cochrane Systematic Reviews, 19-Oct-2005
Second malignancies (SM) are a major late effect of treatment for Hodgkin's disease (HD). Reliable comparisons of SM risk between alternative treatment strategies are lacking. - Chest physiotherapy compared to no chest physiotherapy for cystic fibrosis
Cochrane Systematic Reviews, 21-Dec-2015
Chest physiotherapy is widely used in people with cystic fibrosis in order to clear mucus from the airways. This is an updated version of previously published reviews. - Chest physiotherapy for acute bronchiolitis in paediatric patients between 0 and 24 months old
Cochrane Systematic Reviews, 1-Feb-2016
This Cochrane review was first published in 2005 and updated in 2007, 2012 and now 2015. Acute bronchiolitis is the leading cause of medical emergencies during winter in children younger than two years of age. Chest physiotherapy is sometimes used to assi - Chest physiotherapy for pneumonia in adults
Cochrane Systematic Reviews, 6-Sep-2022
Despite conflicting evidence, chest physiotherapy has been widely used as an adjunctive treatment for adults with pneumonia. This is an update of a review first published in 2010 and updated in 2013. - Chest physiotherapy for pneumonia in children
Cochrane Systematic Reviews, 2-Jan-2019
Pneumonia is a lung infection that causes more deaths in children aged under five years than any other single cause. Chest physiotherapy is widely used as adjuvant treatment for pneumonia. Physiotherapy is thought to help remove inflammatory exudates, tra - Chest physiotherapy for preventing morbidity in babies being extubated from mechanical ventilation
Cochrane Systematic Reviews, 22-Apr-2002
Chest physiotherapy has been used to clear secretions and help lung ventilation in newborns who have needed mechanical ventilation for respiratory problems. However, there are concerns about the safety of some forms of chest physiotherapy. - Chest physiotherapy for reducing respiratory morbidity in infants requiring ventilatory support
Cochrane Systematic Reviews, 13-May-2008
Chest physiotherapy (CPT) has been used in many neonatal nurseries around the world to improve airway clearance and treat lung collapse; however, the evidence to support its use has been conflicting. Despite the large number of studies there is very littl - Chest radiograph in acute respiratory infections
Cochrane Systematic Reviews, 21-Jul-2009
Chest radiography is widely used during the management of acute lower respiratory infections, but the benefits are unknown. - Chest radiographs for acute lower respiratory tract infections
Cochrane Systematic Reviews, 24-Dec-2013
Acute lower respiratory tract infections (LRTIs) (e.g. pneumonia) are a major cause of morbidity and mortality and management focuses on early treatment. Chest radiographs (X-rays) are one of the commonly used strategies. Although radiological facilities - Chest shielding for prevention of a haemodynamically significant patent ductus arteriosus in preterm infants receiving phototherapy
Cochrane Systematic Reviews, 3-Nov-2015
Patent ductus arteriosus (PDA) is associated with mortality and morbidity in preterm infants. Phototherapy is a common treatment for jaundice in preterm infants. However, phototherapy has been associated with failure of closure of the ductus arteriosus in - Chest ultrasonography versus supine chest radiography for diagnosis of pneumothorax in trauma patients in the emergency department
Cochrane Systematic Reviews, 23-Jul-2020
Chest X-ray (CXR) is a longstanding method for the diagnosis of pneumothorax but chest ultrasonography (CUS) may be a safer, more rapid, and more accurate modality in trauma patients at the bedside that does not expose the patient to ionizing radiation. T - Chewing gum for enhancing early recovery of bowel function after caesarean section
Cochrane Systematic Reviews, 17-Oct-2016
Caesarean sections (CS) are the most frequent major surgery in the world. A transient impairment of bowel motility is expected after CS. Although this usually resolves spontaneously within a few days, it can cause considerable discomfort, require symptoma - Chewing gum for postoperative recovery of gastrointestinal function
Cochrane Systematic Reviews, 21-May-2015
Ileus commonly occurs after abdominal surgery, and is associated with complications and increased length of hospital stay (LOHS). Onset of ileus is considered to be multifactorial, and a variety of preventative methods have been investigated. Chewing gum - Child protection training for professionals to improve reporting of child abuse and neglect
Cochrane Systematic Reviews, 5-Jul-2022
Many nations require child-serving professionals to report known or suspected cases of significant child abuse and neglect to statutory child protection or safeguarding authorities. Considered globally, there are millions of professionals who fulfil these - Chimeric antigen receptor (CAR) T‐cell therapy for people with relapsed or refractory diffuse large B‐cell lymphoma
Cochrane Systematic Reviews, 13-Sep-2021
Diffuse large B-cell lymphoma (DLBCL) is an aggressive cancer of the lymphatic system. About 30% to 40% of people with DLBCL experience relapse and 10% are refractory to first-line treatment usually consisting of R-CHOP chemotherapy. Of those eligible for - Chinese herbal medicine for atopic eczema
Cochrane Systematic Reviews, 11-Sep-2013
Traditional Chinese herbal mixtures have been used to treat atopic eczema for many years. Their efficacy has attracted public attention and recently some clinical trials have been undertaken. - Chinese herbal medicine for atopic eczema
Cochrane Systematic Reviews, 9-Dec-2015
Chinese herbal medicine (CHM) has been increasingly used for atopic eczema. A previous version of this Cochrane review published in 2004 found some evidence of a possible benefit for oral ingestion of CHM for eczema, but the results were inconclusive and
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