- Celecoxib for osteoarthritis
Cochrane Systematic Reviews, 22-May-2017
Osteoarthritis (OA) is the most common form of arthritis and is caused by degeneration of the joint cartilage and growth of new bone, cartilage and connective tissue. It is often associated with major disability and impaired quality of life. There is curr - Celecoxib for rheumatoid arthritis
Cochrane Systematic Reviews, 9-Jun-2017
Rheumatoid arthritis (RA) is a systemic auto-immune disorder, involving persistent joint inflammation. NSAIDs are used to control the symptoms of RA, but are associated with significant gastro-intestinal toxicity, including a risk of potentially life thre - Celecoxib for rheumatoid arthritis
Cochrane Systematic Reviews, 9-Jun-2017
Rheumatoid arthritis is a systemic auto-immune disorder that causes widespread and persistent inflammation of the synovial lining of joints and tendon sheaths. Presently, there is no cure for rheumatoid arthritis and treatment focuses on managing symptoms - Celiac plexus block for pancreatic cancer pain in adults
Cochrane Systematic Reviews, 16-Mar-2011
Pancreatic cancer causes severe pain in 50 to 70% of patients and is often difficult to treat. Celiac plexus block (CPB) is thought to be a safe and effective technique for reducing the severity of pain. - Cell salvage for minimising perioperative allogeneic blood transfusion
Cochrane Systematic Reviews, 14-Apr-2010
Concerns regarding the safety of transfused blood have prompted reconsideration of the use of allogeneic (from an unrelated donor) red blood cell (RBC) transfusion, and a range of techniques to minimise transfusion requirements. - Cell salvage in emergency trauma surgery
Cochrane Systematic Reviews, 23-Jan-2015
Trauma is the leading cause of death in people under the age of 45 years. Over the past 20 years, intraoperative autologous transfusions (obtained by cell salvage, also known as intraoperative blood salvage (IBS)) have been used as an alternative to blood - Cell‐based therapies for amyotrophic lateral sclerosis/motor neuron disease
Cochrane Systematic Reviews, 19-Dec-2019
Amyotrophic lateral sclerosis (ALS), which is also known as motor neuron disease (MND), is a fatal disease associated with rapidly progressive disability, for which no definitive treatment exists. Current treatment approaches largely focus on relieving sy - Cellulose, modified cellulose and synthetic membranes in the haemodialysis of patients with end‐stage renal disease
Cochrane Systematic Reviews, 20-Jul-2005
When the kidney fails the blood-borne metabolites of protein breakdown and water cannot be excreted. The principle of haemodialysis is that such substances can be removed when blood is passed over a semipermeable membrane. Natural membrane materials inclu - Cemented, cementless or hybrid fixation options in total knee arthroplasty for osteoarthritis and other non-traumatic diseases
Cochrane Systematic Reviews, 27-Aug-2012
It is not clear which fixation of total knee arthroplasty obtains the best clinical, functional and radiographic results in people with osteoarthritis and other non-traumatic diseases, such as rheumatoid arthritis. - Central action beta‐blockers versus placebo for neuroleptic‐induced acute akathisia
Cochrane Systematic Reviews, 18-Oct-2004
Neuroleptic-induced akathisia is a common, distressing early-onset adverse effect of neuroleptic drugs. It has been associated with poor treatment compliance and an increased risk of relapse. - Central venous access sites for the prevention of venous thrombosis, stenosis and infection
Cochrane Systematic Reviews, 14-Mar-2012
Central venous access (CVA) is widely used. However, its thrombotic, stenotic and infectious complications can be life-threatening and involve high-cost therapy. Research revealed that the risk of catheter-related complications varied according to the sit - Central venous catheter (CVC) removal for patients of all ages with candidaemia
Cochrane Systematic Reviews, 11-Jul-2016
Candida bloodstream infections most often affect those already suffering serious, potentially life-threatening conditions and often cause significant morbidity and mortality. Most affected persons have a central venous catheter (CVC) in place. The best CV - Centralisation of services for gynaecological cancer
Cochrane Systematic Reviews, 21-Sep-2016
Gynaecological cancers are the second most common cancers among women. It has been suggested that centralised care improves outcomes but consensus is lacking. - Centre-based day care for children younger than five years of age in high-income countries
Cochrane Systematic Reviews, 22-Sep-2014
A large proportion of children younger than five years of age in high-income countries experience significant non-parental care. Centre-based day care services may influence the development of children and the economic situation of parents. - Centre-based day care for children younger than five years of age in low- and middle-income countries
Cochrane Systematic Reviews, 22-Sep-2014
Because of poverty, children and families in low- and middle-income countries often face significant impediments to health and well-being. Centre-based day care services may influence the development of children and the economic situation of parents by pr - Cephalic version by moxibustion for breech presentation
Cochrane Systematic Reviews, 3-Apr-2012
Moxibustion (a type of Chinese medicine which involves burning a herb close to the skin) to the acupuncture point Bladder 67 (BL67) (Chinese name Zhiyin), located at the tip of the fifth toe, has been proposed as a way of correcting breech presentation. - Cephalic version by postural management for breech presentation
Cochrane Systematic Reviews, 17-Oct-2012
Babies with breech presentation (bottom first) are at increased risk of complications during birth, and are often delivered by caesarean section. The chance of breech presentation persisting at the time of delivery, and the risk of caesarean section, can - Cephalomedullary nails versus extramedullary implants for extracapsular hip fractures in older adults
Cochrane Systematic Reviews, 26-Jan-2022
Hip fractures are a major healthcare problem, presenting a substantial challenge and burden to patients, healthcare systems and society. The increased proportion of older adults in the world population means that the absolute number of hip fractures is ri - Ceramic inlays for restoring posterior teeth
Cochrane Systematic Reviews, 29-Sep-2015
In recent decades ceramic inlays have been used with the increasing requirements from patients for tooth-coloured restorations in posterior teeth. Ceramic inlays can offer an excellent appearance, however, their long-term prognosis is uncertain, as only a - Cerebral near‐infrared spectroscopy (NIRS) for perioperative monitoring of brain oxygenation in children and adults
Cochrane Systematic Reviews, 17-Jan-2018
Various techniques have been employed for the early detection of perioperative cerebral ischaemia and hypoxia. Cerebral near-infrared spectroscopy (NIRS) is increasingly used in this clinical scenario to monitor brain oxygenation. However, it is unknown w
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