- Carnitine supplementation for inborn errors of metabolism
Cochrane Systematic Reviews, 15-Feb-2012
Inborn errors of metabolism are genetic conditions which can lead to abnormalities in the synthesis and metabolism of proteins, carbohydrates, or fats. It has been proposed that in some instances carnitine supplementation should be provided to infants wit - Carnitine supplementation for preterm infants with recurrent apnoea
Cochrane Systematic Reviews, 20-Oct-2003
Apnea of prematurity is a common problem in preterm infants in the neonatal intensive care setting (NICU) often delaying their discharge home or transfer to a step down unit. Premature infants are at increased risk of carnitine deficiency. Carnitine suppl - Carnitine supplementation of parenterally fed neonates
Cochrane Systematic Reviews, 23-Oct-2000
Carnitine, a quaternary amino acid, plays an important role in the oxidation of long chain fatty acids. Both breast milk and infant formulas contain carnitine. However, it is not routinely provided in parenteral nutrition solutions. Non supplemented paren - Carnitine supplements for people with chronic kidney disease requiring dialysis
Cochrane Systematic Reviews, 6-Dec-2022
Carnitine deficiency is common in patients with chronic kidney disease (CKD) who require dialysis. Several clinical studies have suggested that carnitine supplementation is beneficial for dialysis-related symptoms. However, the clinical effectiveness and - Carotid artery stenting versus endarterectomy for treatment of carotid artery stenosis
Cochrane Systematic Reviews, 25-Feb-2020
Carotid artery stenting is an alternative to carotid endarterectomy for the treatment of atherosclerotic carotid artery stenosis. This review updates a previous version first published in 1997 and subsequently updated in 2004, 2007, and 2012. - Carotid endarterectomy for asymptomatic carotid stenosis
Cochrane Systematic Reviews, 19-Oct-2005
Carotid endarterectomy (CEA) is of proven benefit in recently-symptomatic patients with severe carotid stenosis. Its role in asymptomatic stenosis is still debated. The Asymptomatic Carotid Surgery Trial (ACST) more than doubled the number of patients ran - Carotid endarterectomy for carotid stenosis in patients selected for coronary artery bypass graft surgery
Cochrane Systematic Reviews, 7-Oct-2009
Carotid stenosis and coronary artery disease can occur simultaneously. In patients with coronary artery disease who are scheduled for coronary artery bypass graft (CABG) surgery, but who also have carotid artery stenosis, there is controversy about the ro - Carotid endarterectomy for symptomatic carotid stenosis
Cochrane Systematic Reviews, 12-Sep-2020
Stroke is the third leading cause of death and the most common cause of long-term disability. Severe narrowing (stenosis) of the carotid artery is an important cause of stroke. Surgical treatment (carotid endarterectomy) may reduce the risk of stroke, but - Carvedilol versus traditional, non‐selective beta‐blockers for adults with cirrhosis and gastroesophageal varices
Cochrane Systematic Reviews, 29-Oct-2018
Non-selective beta-blockers are recommended for the prevention of bleeding in people with cirrhosis, portal hypertension and gastroesophageal varices. Carvedilol is a non-selective beta-blocker with additional intrinsic alpha1-blocking effects, which may - Case management approaches to home support for people with dementia
Cochrane Systematic Reviews, 13-Oct-2015
Over 35 million people are estimated to be living with dementia in the world and the societal costs are very high. Case management is a widely used and strongly promoted complex intervention for organising and co-ordinating care at the level of the indivi - Case management for persons with substance use disorders
Cochrane Systematic Reviews, 15-Apr-2014
Patients with alcohol and other drug use disorders (AOD) frequently have multiple social, physical, and mental health treatment needs, yet have difficulty accessing community services, including drug abuse treatment. One strategy for linking patients with - Caseworker‐assigned discharge plans to prevent hospital readmission for acute exacerbations in children with chronic respiratory illness
Cochrane Systematic Reviews, 2-Nov-2018
Chronic respiratory conditions are major causes of mortality and morbidity. Children with chronic health conditions have increased morbidity associated with their physical, emotional, and general well-being. Acute respiratory exacerbations (AREs) are comm - Castor oil, bath and/or enema for cervical priming and induction of labour
Cochrane Systematic Reviews, 24-Jul-2013
Castor oil, a potent cathartic, is derived from the bean of the castor plant. Anecdotal reports, which date back to ancient Egypt have suggested the use of castor oil to stimulate labour. Castor oil has been widely used as a traditional method of initiati - Catechol‐O‐methyltransferase inhibitors for levodopa‐induced complications in Parkinson's disease
Cochrane Systematic Reviews, 18-Oct-2004
As Parkinson's disease progresses the control of motor symptoms often requires the addition of other drugs to levodopa. The principle aim of COMT inhibitor therapy is to increase the duration of effect of each levodopa dose and thus reduce the time patien - Catechol‐O‐methyltransferase inhibitors versus active comparators for levodopa‐induced complications in Parkinson's disease
Cochrane Systematic Reviews, 18-Oct-2004
As Parkinson's disease progresses the control of the symptoms often requires the addition of other drugs to levodopa. The principle aim of COMT inhibitor therapy is to increase the duration of effect of the levodopa dose and thus reduce the time patients - Catheter ablation for paroxysmal and persistent atrial fibrillation
Cochrane Systematic Reviews, 13-Mar-2012
Atrial fibrillation (AF) is the most common cardiac arrhythmia seen in cardiovascular departments. Treatments include medical interventions and catheter ablation. Due to uncertainties in medical therapies for AF, and the need to continue sinus rhythm, abl - Catheter impregnation, coating or bonding for reducing central venous catheter‐related infections in adults
Cochrane Systematic Reviews, 16-Mar-2016
The central venous catheter (CVC) is essential in managing acutely ill patients in hospitals. Bloodstream infection is a major complication in patients with a CVC. Several infection control measures have been developed to reduce bloodstream infections, on - Catheter insertion techniques for improving catheter function and clinical outcomes in peritoneal dialysis patients
Cochrane Systematic Reviews, 22-Feb-2023
Peritoneal dialysis (PD) relies on the optimal functionality of the flexible plastic PD catheter present within the peritoneal cavity to enable effective treatment. As a result of limited evidence, it is uncertain if the PD catheter's insertion method inf - Catheter policies for management of long term voiding problems in adults with neurogenic bladder disorders
Cochrane Systematic Reviews, 6-Nov-2013
Management of the neurogenic bladder has the primary objectives of maintaining continence, ensuring low bladder pressure (to avoid renal damage) and avoiding or minimising infection. Options include intermittent urethral catheterisation, indwelling urethr - Catheter type, placement and insertion techniques for preventing catheter‐related infections in chronic peritoneal dialysis patients
Cochrane Systematic Reviews, 31-May-2019
Peritonitis is one of the limiting factors for the growth of peritoneal dialysis (PD) worldwide and is a major cause of technique failure. Several studies have examined the effectiveness of various catheter-related interventions for lowering the risk of P
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