- Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Human immunodeficiency virus-associated nephropathy (HIVAN) is the most common cause of end stage kidney disease (ESKD) in human immunodeficiency virus-1 (HIV-1) serotype patients and it mostly affects patients of African descent. It rapidly progresses to - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Rubefacients containing salicylates cause irritation of the skin and are believed to relieve various musculoskeletal pains. They are available on prescription, and are common components in over-the-counter remedies. This is an update of a review of rubefa - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Central giant cell granuloma (CGCG) of the jaws is a rare benign tumour with an unknown aetiology accounting for up to 7% of tumours in the mandible (lower jaw) and the maxilla (upper jaw). - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
A previous systematic review found that giving neoadjuvant chemotherapy before surgery improved survival compared with radiotherapy. However, the role of neoadjuvant chemotherapy followed by surgery versus surgery alone is still unclear. - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Chronic non-cancer pain, a disabling and distressing condition, is common in adults. It is a global public health problem and economic burden on health and social care systems and on people with chronic pain. Psychological treatments aim to reduce pain, d - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Incontinence is a common and embarrassing problem which has a profound effect on social and psychological well-being. Many people wear absorbent products to contain urine and/or faeces and protect their clothes and dignity. Users of absorbent pads are ver - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Hot flushes are the most common menopausal vasomotor symptom. Hormone therapy (HT) has frequently been recommended for relief of hot flushes, but concerns about the health risks of HT have encouraged women to seek alternative treatments. It has been sugge - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
The inability to have children affects 10% to 15% of couples worldwide. A male factor is estimated to account for up to half of the infertility cases with between 25% to 87% of male subfertility considered to be due to the effect of oxidative stress. Oral - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Active management of the third stage of labour involves giving a prophylactic uterotonic, early cord clamping and controlled cord traction to deliver the placenta. With expectant management, signs of placental separation are awaited and the placenta is de - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
This review is an update of a previously published review in the Cochrane Database of Systematic Reviews (2010, Issue 9 and 2013, Issue 6). Epithelial ovarian cancer accounts for about 90% of all cases of ovarian cancer. Debulking surgery and six courses - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
High grade glioma (HGG) is an aggressive form of brain cancer. Treatment of HGG usually entails biopsy, or resection if safe, followed by radiotherapy. Temozolomide is a novel oral chemotherapy drug that penetrates into the brain and purportedly has a low - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Ocular infection caused by Toxoplasma gondii, a parasite, may result in inflammation in the retina, choroid, and uvea, and consequently lead to complications such as glaucoma, cataract, and posterior synechiae. - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Diabetic macular oedema (DMO) is a common complication of diabetic retinopathy. Antiangiogenic therapy with anti-vascular endothelial growth factor (anti-VEGF) can reduce oedema, improve vision and prevent further visual loss. These drugs have replaced la - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
This is an update of a Cochrane Review first published in the Cochrane Library (2010, Issue 7). - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Dietary fluoride supplements were first introduced to provide systemic fluoride in areas where water fluoridation is not available. Since 1990, the use of fluoride supplements in caries prevention has been re-evaluated in several countries. - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Anterior cruciate ligament (ACL) reconstruction is one of the most frequently performed orthopaedic procedures. The most common technical cause of reconstruction failure is graft malpositioning. Computer-assisted surgery (CAS) aims to improve the accuracy - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Repeated use of postcoital hormonal contraception is not currently recommended due to the higher risk of side effects and lower contraceptive effectiveness compared to other modern methods of contraception. However, emerging evidence indicates renewed int - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Anaphylaxis is a serious hypersensitivity reaction that is rapid in onset and may result in death. Anaphylaxis guidelines recommend glucocorticoids for the treatment of people experiencing anaphylaxis. - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Chronic heart failure (CHF) is a leading cause of morbidity and mortality worldwide. Anaemia is a common (12-55%) co-morbid condition and is associated with worsening symptoms and increased mortality. Anaemia is treatable and can be targeted in the treatm - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Liver transplantation is an established treatment option for end-stage liver failure. Now that newer, more potent immunosuppressants have been developed, glucocorticosteroids may no longer be needed and their removal may prevent adverse effects.
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