- Cesarean delivery for the prevention of anal incontinence
Cochrane Systematic Reviews, 17-May-2017
Caesarean delivery (CD) is a common form of delivery of a baby, rising in frequency. One reason for its performance is to preserve maternal pelvic floor function, part of which is anal continence. - Cessation of medication for people with schizophrenia already stable on chlorpromazine
Cochrane Systematic Reviews, 4-Dec-2013
Chlorpromazine, one of the first generation of antipsychotic drugs, is effective in the treatment of schizophrenia. For most people schizophrenia is a life-long disorder but about a quarter of those who have a first psychotic breakdown do not go on to exp - Chelation for autism spectrum disorder (ASD)
Cochrane Systematic Reviews, 7-Oct-2016
It has been suggested that the severity of autism spectrum disorder (ASD) symptoms is positively correlated with the level of circulating or stored toxic metals, and that excretion of these heavy metals, brought about by the use of pharmaceutical chelatin - Chelation therapy for atherosclerotic cardiovascular disease
Cochrane Systematic Reviews, 28-May-2008
Chelation therapy is being promoted and practiced all over the world as a form of alternative medicine in the treatment of atherosclerotic cardiovascular disease. It has been recommended as a safe, relatively inexpensive and non-surgical method of restori - Chemical pleurodesis versus surgical intervention for persistent and recurrent pneumothoraces in cystic fibrosis
Cochrane Systematic Reviews, 13-Apr-2015
Pneumothorax is a potentially life-threatening complication for people with cystic fibrosis. Spontaneous pneumothorax is the presence of air in the pleural space and can be subdivided into first episode and recurrent. The recurrence of pneumothorax is whe - Chemoimmunotherapy versus chemotherapy for metastatic malignant melanoma
Cochrane Systematic Reviews, 6-Feb-2018
Malignant melanoma, one of the most aggressive of all skin cancers, is increasing in incidence throughout the world. Surgery remains the cornerstone of curative treatment in earlier stages. Metastatic disease is incurable in most affected people, because - Chemoradiation for advanced primary vulval cancer
Cochrane Systematic Reviews, 21-Sep-2016
Vulval cancer is a rare gynaecological cancer. There is no standard approach for treating locally advanced primary vulval cancer (FIGO stage III and IV). Combined treatment modalities have been developed using radiotherapy, chemotherapy and surgery. The a - Chemoradiotherapy versus chemoradiotherapy plus surgery for esophageal cancer
Cochrane Systematic Reviews, 22-Aug-2017
Please see Appendix 4 for a glossary of terms. - Chemotherapy alone versus chemotherapy plus radiotherapy for adults with early stage Hodgkin lymphoma
Cochrane Systematic Reviews, 27-Apr-2017
Combined modality treatment consisting of chemotherapy followed by localised radiotherapy is the standard treatment for patients with early stage Hodgkin lymphoma (HL). However, due to long- term adverse effects such as secondary malignancies the role of - Chemotherapy alone versus endocrine therapy alone for metastatic breast cancer
Cochrane Systematic Reviews, 24-May-2011
Both chemotherapy and endocrine therapy can be used as treatments for metastatic breast cancer. - Chemotherapy and radiotherapy for advanced pancreatic cancer
Cochrane Systematic Reviews, 11-Mar-2018
Pancreatic cancer (PC) is a highly lethal disease with few effective treatment options. Over the past few decades, many anti-cancer therapies have been tested in the locally advanced and metastatic setting, with mixed results. This review attempts to synt - Chemotherapy and radiotherapy for inoperable advanced pancreatic cancer
Cochrane Systematic Reviews, 5-Aug-2009
Pancreatic cancer has a poor prognosis. The benefit of chemotherapy, radiotherapy or both as a palliative treatment of advanced or relapsed disease is uncertain. - Chemotherapy and supportive care versus supportive care alone for advanced non-small cell lung cancer
Cochrane Systematic Reviews, 12-Sep-2012
Since our individual patient data (IPD) meta-analysis of supportive care and chemotherapy for non-small cell lung cancer (NSCLC), published in 1995, many trials have been completed. We have carried out an updated IPD meta-analysis to assess newer regimens - Chemotherapy and surgery versus surgery alone in non-small cell lung cancer
Cochrane Systematic Reviews, 17-Sep-2008
The role of pre-operative chemotherapy in the treatment of patients with non-small cell lung cancer (NSCLC) was not clear. A systematic review and quantitative meta-analysis were therefore undertaken to evaluate the available evidence from randomised tria - Chemotherapy and/or radiotherapy in combination with surgery for ovarian carcinosarcoma
Cochrane Systematic Reviews, 23-Sep-2019
Ovarian carcinosarcoma, also known as malignant mixed Mullerian tumour, is a rare malignant gynaecological tumour constituting about 1% or less of all ovarian cancers. In over 80% of cases, there is extra-ovarian intra-abdominal spread at diagnosis. The p - Chemotherapy as an adjunct to radiotherapy in locally advanced nasopharyngeal carcinoma
Cochrane Systematic Reviews, 27-Apr-2015
A previous meta-analysis investigated the role of chemotherapy in head and neck locally advanced carcinoma. This work had not been performed on nasopharyngeal carcinoma. - Chemotherapy for advanced gastric cancer
Cochrane Systematic Reviews, 25-Aug-2017
Gastric cancer is the fifth most common cancer worldwide. In "Western" countries, most people are either diagnosed at an advanced stage, or develop a relapse after surgery with curative intent. In people with advanced disease, significant benefits from ta - Chemotherapy for advanced non-small cell lung cancer in the elderly population
Cochrane Systematic Reviews, 25-Sep-2019
Approximately 50% of patients with newly diagnosed non-small cell lung cancer (NSCLC) are over 70 years of age at diagnosis. Despite this fact, these patients are underrepresented in randomized controlled trials (RCTs). As a consequence, the most appropri - Chemotherapy for advanced ovarian cancer
Cochrane Systematic Reviews, 21-Feb-2011
Ovarian carcinoma is the seventh commonest female cancer worldwide and is responsible for the greatest number of deaths from gynaecological malignancy in Europe and North America. Although many studies have explored the use of chemotherapy in this disease - Chemotherapy for advanced, recurrent or metastatic endometrial carcinoma
Cochrane Systematic Reviews, 11-Feb-2015
Although endometrial adenocarcinoma is a common gynaecological cancer, a comparatively small proportion of patients present with, or develop, recurrent or advanced disease. However, for those women whose disease does progress or recur the prognosis is poo
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