- Bladder neck needle suspension for urinary incontinence in women
Cochrane Systematic Reviews, 25-Jul-2017
Bladder neck needle suspension is an operation traditionally used for moderate or severe stress urinary incontinence in women. About a third of adult women experience some urinary incontinence, and about a third of these have moderate or severe symptoms. - Bladder training for urinary incontinence in adults
Cochrane Systematic Reviews, 26-Jan-2004
Urinary incontinence is a common and distressing problem. Bladder training aims to increase the interval between voids and is widely used for the treatment of urinary incontinence. - Blood biomarkers for the non‐invasive diagnosis of endometriosis
Cochrane Systematic Reviews, 1-May-2016
About 10% of reproductive-aged women suffer from endometriosis, a costly chronic disease causing pelvic pain and subfertility. Laparoscopy is the gold standard diagnostic test for endometriosis, but is expensive and carries surgical risks. Currently, ther - Blood CEA levels for detecting recurrent colorectal cancer
Cochrane Systematic Reviews, 10-Dec-2015
Testing for carcino-embryonic antigen (CEA) in the blood is a recommended part of follow-up to detect recurrence of colorectal cancer following primary curative treatment. There is substantial clinical variation in the cut-off level applied to trigger fur - Blood pressure control for diabetic retinopathy
Cochrane Systematic Reviews, 28-Jan-2015
Diabetic retinopathy is a common complication of diabetes and a leading cause of visual impairment and blindness. Research has established the importance of blood glucose control to prevent development and progression of the ocular complications of diabet - Blood pressure lowering efficacy of alpha blockers for primary hypertension
Cochrane Systematic Reviews, 15-Aug-2012
Alpha blockers are occasionally prescribed for hypertension so it is important to determine and compare their effects on blood pressure (BP), heart rate and withdrawals due to adverse effects (WDAE). - Blood pressure lowering efficacy of angiotensin converting enzyme (ACE) inhibitors for primary hypertension
Cochrane Systematic Reviews, 8-Oct-2008
ACE inhibitors are widely prescribed for hypertension so it is essential to determine and compare their effects on blood pressure (BP), heart rate and withdrawals due to adverse effects (WDAE). - Blood pressure lowering efficacy of angiotensin receptor blockers for primary hypertension
Cochrane Systematic Reviews, 8-Oct-2008
Angiotensin receptor blockers (ARBs) are widely prescribed for hypertension so it is essential to determine and compare their effects on blood pressure (BP), heart rate and withdrawals due to adverse effects (WDAE). - Blood pressure lowering efficacy of beta‐1 selective beta blockers for primary hypertension
Cochrane Systematic Reviews, 10-Mar-2016
Beta blockers are commonly used to treat hypertension. The blood pressure reading is the primary tool for physicians and patients to assess the efficacy of the treatment. The blood pressure lowering effect of beta-1 selective blockers is not known. - Blood pressure lowering efficacy of beta‐blockers as second‐line therapy for primary hypertension
Cochrane Systematic Reviews, 20-Jan-2010
Beta-blockers are one of the more commonly prescribed classes of anti-hypertensive drugs, both as first-line and second-line. - Blood pressure lowering efficacy of coenzyme Q10 for primary hypertension
Cochrane Systematic Reviews, 3-Mar-2016
Blood pressure is a commonly measured risk factor for non-fatal and fatal cardiovascular adverse events such as heart attacks and strokes. Clinical trials have suggested that coenzyme Q10, a non-prescription nutritional supplement, can effectively lower b - Blood pressure lowering efficacy of diuretics as second-line therapy for primary hypertension
Cochrane Systematic Reviews, 12-Aug-2009
Diuretics are widely prescribed for hypertension not only as a first-line drug but also as a second-line drug. Therefore, it is essential to determine the effects of diuretics on blood pressure (BP), heart rate and withdrawals due to adverse effects (WDAE - Blood pressure lowering efficacy of dual alpha and beta blockers for primary hypertension
Cochrane Systematic Reviews, 26-Aug-2015
Drugs with combined alpha and beta blocking activity are commonly prescribed to treat hypertension. However, the blood pressure (BP) lowering efficacy of this class of beta blockers has not been systematically reviewed and quantified. - Blood pressure lowering efficacy of nonselective beta-blockers for primary hypertension
Cochrane Systematic Reviews, 28-Feb-2014
Beta-blockers are one of the classes of drugs frequently used to treat hypertension. Quantifying the blood pressure (BP) lowering effects of nonselective beta-blockers provides important information that aids clinical decision making. - Blood pressure lowering efficacy of partial agonist beta blocker monotherapy for primary hypertension
Cochrane Systematic Reviews, 27-Nov-2014
Partial agonists are a subclass of beta blockers used to treat hypertension in many countries. Partial agonist act by stimulating beta receptors when they are quiescent and blocking beta receptors when they are active. The blood pressure (BP) lowering eff - Blood pressure lowering efficacy of potassium‐sparing diuretics (that block the epithelial sodium channel) for primary hypertension
Cochrane Systematic Reviews, 14-Nov-2012
Potassium-sparing diuretics, which block the epithelial sodium channel (ENaC), are widely prescribed for hypertension as a second-line drug in patients taking other diuretics (e.g. thiazide diuretics) and much less commonly prescribed as monotherapy. Ther - Blood pressure lowering efficacy of renin inhibitors for primary hypertension
Cochrane Systematic Reviews, 5-Apr-2017
Hypertension is a chronic condition associated with an increased risk of mortality and morbidity. Renin is the enzyme responsible for converting angiotensinogen to angiotensin I, which is then converted to angiotensin II. Renin inhibitors are a new class - Blood pressure targets for hypertension in older adults
Cochrane Systematic Reviews, 8-Aug-2017
Eight out of 10 major antihypertensive trials in older adults attempted to achieve a target systolic blood pressure (BP) less than 160 mmHg. Collectively these trials demonstrated benefit for treatment, as compared to no treatment, for an older adult with - Blood pressure targets for hypertension in people with diabetes mellitus
Cochrane Systematic Reviews, 31-Oct-2013
When treating elevated blood pressure (BP), doctors often want to know what blood pressure target they should try to achieve. The standard blood pressure target in clinical practice for some time has been less than 140 - 160/90 - 100 mmHg for the general - Blood pressure targets for the treatment of people with hypertension and cardiovascular disease
Cochrane Systematic Reviews, 9-Sep-2020
This is the second update of the review first published in 2017.
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