- Calcimimetics for secondary hyperparathyroidism in chronic kidney disease patients
Cochrane Systematic Reviews, 9-Dec-2014
Calcimimetic agents lower abnormal serum parathyroid hormone (PTH) levels in people who have chronic kidney disease (CKD), but the benefits and harms on patient-level outcomes are uncertain. Since this review was first published in 2006 showing that evide - Calcineurin inhibitor minimisation versus continuation of calcineurin inhibitor treatment for liver transplant recipients
Cochrane Systematic Reviews, 14-Feb-2012
The therapeutic success of liver transplantation has been largely attributable to the development of effective immunosuppressive treatment regimens. In particular, calcineurin inhibitors were essential in reducing acute rejection and improving early survi - Calcitonin for metastatic bone pain
Cochrane Systematic Reviews, 9-Jul-2015
Pain is the most frequent symptom experienced by cancer patients, its intensity dependent on the site of the tumour. Tumours that compromise bone or nervous structures due to the bone destruction process are the most painful. There are several treatments - Calcitonin for preventing and treating corticosteroid-induced osteoporosis
Cochrane Systematic Reviews, 24-May-2010
Corticosteroid-induced osteoporosis is a cause of morbidity in patients with chronic obstructive lung disease, asthma, and rheumatologic disorders. Corticosteroid treatment causes bone loss by a variety of complex mechanisms. It has been shown that bone m - Calcium and phosphorus supplementation of human milk for preterm infants
Cochrane Systematic Reviews, 26-Feb-2017
Preterm infants are born with low skeletal stores of calcium and phosphorus. Preterm human milk provides insufficient calcium and phosphorus to meet the estimated needs of preterm infants for adequate growth. Supplementation of human milk with calcium and - Calcium and vitamin D for corticosteroid-induced osteoporosis
Cochrane Systematic Reviews, 24-May-2010
Osteoporosis and subsequent fracture are a major cause of morbidity and mortality. It is defined by low bone mass, and has many etiologies with different patterns of bone loss. Corticosteroid therapy is a contributor to the development of osteoporosis. St - Calcium antagonists as an add-on therapy for drug-resistant epilepsy
Cochrane Systematic Reviews, 27-Feb-2013
This is an updated version of the original Cochrane review published in The Cochrane Library 2001, Issue 4. - Calcium antagonists for acute ischemic stroke
Cochrane Systematic Reviews, 8-Jan-2019
The sudden loss of blood supply in ischemic stroke is associated with an increase of calcium ions within neurons. Inhibiting this increase could protect neurons and might reduce neurological impairment, disability, and handicap after stroke. - Calcium antagonists for aneurysmal subarachnoid haemorrhage
Cochrane Systematic Reviews, 22-Jul-2008
Secondary ischaemia is a frequent cause of poor outcome in patients with subarachnoid haemorrhage (SAH). Its pathogenesis has been incompletely elucidated, but vasospasm probably is a contributing factor. Experimental studies have suggested that calcium a - Calcium antagonists for Duchenne muscular dystrophy
Cochrane Systematic Reviews, 15-Feb-2012
Duchenne muscular dystrophy (DMD) is a progressive muscle condition starting in childhood, leading to severe disability and a shortened life span. It is due to severe deficiency of the protein dystrophin which performs both structural and signalling roles - Calcium channel blockers for acute traumatic brain injury
Cochrane Systematic Reviews, 12-Aug-2008
Acute traumatic brain injury is a major cause of death and disability. Calcium channel blockers (calcium antagonists) have been used in an attempt to prevent cerebral vasospasm after injury, maintain blood flow to the brain, and so prevent further damage. - Calcium channel blockers for antipsychotic-induced tardive dyskinesia
Cochrane Systematic Reviews, 26-Mar-2018
Schizophrenia and related disorders affect a sizable proportion of any population. Antipsychotic medications are the primary treatment for these disorders. Antipsychotic medications are associated with a variety of adverse effects including tardive dyskin - Calcium channel blockers for inhibiting preterm labour and birth
Cochrane Systematic Reviews, 2-Jul-2014
Preterm birth is a major contributor to perinatal mortality and morbidity, affecting around 9% of births in high-income countries and an estimated 13% of births in low- and middle-income countries. Tocolytics are drugs used to suppress uterine contraction - Calcium channel blockers for potential impaired fetal growth
Cochrane Systematic Reviews, 2-Aug-2009
Calcium channel blockers may increase the blood flow to the fetus or may improve fetal-placental cellular energy generation. This could enhance fetal growth. - Calcium channel blockers for preventing acute tubular necrosis in kidney transplant recipients
Cochrane Systematic Reviews, 21-Sep-2008
The incidence of delayed graft function in cadaveric grafts has increased over the last few years due in part to the large demand for cadaveric kidneys necessitating the use of kidneys from marginal donors. Calcium channel blockers have the potential to r - Calcium channel blockers for preventing cardiomyopathy due to iron overload in people with transfusion-dependent beta thalassaemia
Cochrane Systematic Reviews, 25-Jun-2018
Beta thalassaemia is a common inherited blood disorder. The need for frequent blood transfusions in this condition poses a difficult problem to healthcare systems. The most common cause of morbidity and mortality is cardiac dysfunction from iron overload. - Calcium channel blockers for primary and secondary Raynaud's phenomenon
Cochrane Systematic Reviews, 29-Nov-2017
Raynaud's phenomenon is a vasospastic disease characterized by digital pallor, cyanosis, and extremity pain. Primary Raynaud's phenomenon is not associated with underlying disease, but secondary Raynaud's phenomenon is associated with connective tissue di - Calcium channel blockers for primary Raynaud's phenomenon
Cochrane Systematic Reviews, 12-Jul-2016
Calcium channel blockers are the most commonly prescribed drugs for people with primary Raynaud's phenomenon. Primary Raynaud's phenomenon is a common condition characterised by an exaggerated vasospastic response to cold or emotion: classically the digit - Calcium channel blockers for pulmonary arterial hypertension
Cochrane Systematic Reviews, 25-Sep-2015
Pulmonary arterial hypertension (PAH) is one of several forms of pulmonary hypertension: a chronic disease of the pulmonary vasculature. The mean age at diagnosis is around 50 years old, with increasing prevalence in people over 70 years old (10% to 17%). - Calcium channel blockers versus other classes of drugs for hypertension
Cochrane Systematic Reviews, 7-Jul-2010
Calcium channel blockers (CCBs) are a relatively new antihypertensive class. The effect of first-line CCBs on the prevention of cardiovascular events, as compared with other antihypertensive drug classes, is unknown.
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