- Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Long-term levodopa therapy in Parkinson's disease is associated with the development of motor complications including abnormal involuntary movements and a shortening response to each dose (wearing off phenomenon). It is thought that dopamine agonists can - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Long-term levodopa therapy in Parkinson's disease is associated with the development of motor complications including abnormal involuntary movements and a shortening response to each dose (wearing off phenomenon). It is thought that dopamine agonists can - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Viral respiratory tract infections in people with cystic fibrosis have a deteriorating effect on their lung function and disease progression. Annual influenza vaccination is therefore commonly recommended for people with cystic fibrosis. - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Stress urinary incontinence constitutes a significant health and economic burden to society. Traditional suburethral slings are surgical operations used to treat women with symptoms of stress urinary incontinence. - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Anterior vaginal repair (anterior colporrhaphy) is an operation traditionally used for moderate or severe stress urinary incontinence (SUI) in women. About a third of adult women experience urinary incontinence. SUI imposes significant health and economic - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Incontinence can have a devastating effect on the lives of sufferers with significant economic implications. Non-surgical treatments such as pelvic floor muscle training and the use of mechanical devices are usually the first line of management, particula - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Faecal incontinence is a debilitating problem with significant medical, social and economic implications. Treatment options include conservative, non-operative interventions (for example pelvic floor muscle training, biofeedback, drugs) and surgical proce - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Complete (full-thickness) rectal prolapse is a lifestyle-altering disability that commonly affects older people. The range of surgical methods available to correct the underlying pelvic floor defects in full-thickness rectal prolapse reflects the lack of - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Vaginismus is an involuntary contraction of the vaginal muscles which makes sexual intercourse difficult or impossible. It is one of the more common female psychosexual problems. Various therapeutic strategies for vaginismus, such as sex therapy and desen - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Measles is a major cause of childhood morbidity and mortality. Vitamin A deficiency is a recognized risk factor for severe measles infections. The World Health Organization (WHO) recommends a daily oral dose of vitamin A for two days to children with meas - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Prior to introducing pneumococcal conjugate vaccines (PCVs), Streptococcus pneumoniae was most commonly isolated from the middle ear fluid of children with acute otitis media (AOM). Reducing nasopharyngeal colonisation of this bacterium by PCVs may lead t - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Diabetes is a common chronic disease that is increasingly managed in primary care. Different systems have been proposed to manage diabetes care. - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Hospitalised patients are at increased risk of developing deep vein thrombosis (DVT) in the lower limb and pelvic veins, on a background of prolonged immobilisation associated with their medical or surgical illness. Patients with DVT are at increased risk - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Varicose vein surgery is a common surgical procedure but there is no consensus regarding the best surgical technique. The use of tourniquets during varicose vein surgery has been advocated as a means of reducing the potential for blood loss during the ope - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Femoro-popliteal bypass is implemented to save limbs that might otherwise require amputation, in patients with ischaemic rest pain or tissue loss; and to improve walking distance in patients with severe life-limiting claudication. Contemporary practice in - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Ulceration of the feet, which can result in loss of limbs and even death, is one of the major health problems for people with diabetes mellitus. - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Treatment of acute asthma is based on rapid reversal of bronchospasm and arresting airway inflammation. There is some evidence that intravenous magnesium can provide additional bronchodilation when given in conjunction with standard bronchodilating agents - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Asthma and gastro-oesophageal reflux are both common medical conditions and often co-exist. Studies have shown conflicting results concerning the effects of lower oesophageal acidification as a trigger of asthma. Furthermore, asthma might precipitate gast - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
People who have had a transient ischaemic attack (TIA) or non-disabling ischaemic stroke have an annual risk of major vascular events of between 4% and 11%. Aspirin reduces this risk by 20% at most. Secondary prevention trials after myocardial infarction - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Vaginal atrophy is a frequent complaint of postmenopausal women; symptoms include vaginal dryness, itching, discomfort and painful intercourse. Systemic treatment for these symptoms in the form of oral hormone replacement therapy is not always necessary.
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