- Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Following a period of mechanical ventilation, post-extubation upper airway obstruction can occur in newborn infants, especially after prolonged, traumatic or multiple intubations. The subsequent increase in upper airway resistance may lead to respiratory - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Umbilical arterial catheters (UACs) are among the most commonly used monitoring methodologies in neonatal intensive care. There seems to be significant variance between neonatal intensive care units in exactly how these catheters are used. This variance i - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Umbilical arterial catheters (UACs) are among the most commonly used monitoring methodologies in neonatal intensive care. Immediately after insertion of a UAC, local vascular compromise is frequently evident, usually in the form of blue or white toes, but - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Inhaled nitric oxide (iNO) is effective in term infants with hypoxic respiratory failure. The pathophysiology of respiratory failure and the potential risks of iNO differ substantially in preterm infants, necessitating specific study in this population. - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Asymptomatic bacteriuria is a bacterial infection of the urine without any of the typical symptoms that are associated with a urinary infection, and occurs in 2% to 15% of pregnancies. If left untreated, up to 30% of mothers will develop acute pyelonephri - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
A previous Cochrane systematic review has shown that antibiotic drug treatment of asymptomatic bacteriuria in pregnant women substantially decreases the risk of pyelonephritis and reduces the risk of preterm delivery. However, it is not clear whether sing - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Respiratory distress syndrome (RDS) is caused by a deficiency or dysfunction of pulmonary surfactant. A variety of animal derived surfactant extracts have been formulated and given to infants at risk of developing RDS. - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Hydrotubation with oil-soluble contrast media for unexplained infertility and adhesiolysis for infertility due to peritubal adhesions are primary procedures that are of recognised benefit. It is less clear whether postoperative procedures such as hydrotub - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Anticoagulant treatment for intermittent claudication might improve functional capacity and prevent acute cardiovascular complications caused by peripheral obstructive arterial disease. This is an update of the review first published in 2001. - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Bypass surgery is one of the mainstay treatments for patients with critical lower limb ischaemia (CLI). This is the second update of the review first published in 2000. - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
People with venous thromboembolism (VTE) generally are treated for five days with intravenous unfractionated heparin or subcutaneous low-molecular-weight heparin (LMWH), followed by three months of vitamin K antagonists (VKAs). Treatment with VKAs require - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Recombinant interferons have been shown to suppress both the clinical and magnetic resonance imaging (MRI) measures of disease activity in patients with relapsing remitting multiple sclerosis (RRMS). - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Beta-blockers refer to a mixed group of drugs with diverse pharmacodynamic and pharmacokinetic properties. They have shown long-term beneficial effects on mortality and cardiovascular disease (CVD) when used in people with heart failure or acute myocardia - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Treatment of cerebral venous sinus thrombosis with anticoagulants has been controversial. Anticoagulants may prevent new venous infarcts, neurologic deterioration and pulmonary embolism but may also promote haemorrhages. - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
For centuries, there has been controversy around whether being upright (sitting, birthing stools, chairs, squatting, kneeling) or lying down (lateral (Sim's) position, semi-recumbent, lithotomy position, Trendelenburg's position) have advantages for women - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Choice of antibiotic, and the use of single or combined therapy are controversial areas in the treatment of respiratory infection due to Pseudomonas aeruginosa in cystic fibrosis (CF). Advantages of combination therapy include wider range of modes of acti - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Disease-related malnutrition has been reported in 10% to 55% of people in hospital and the community. Dietary advice encouraging the use of energy- and nutrient-rich foods rather than oral nutritional supplements has been suggested as the initial approach - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
People with cystic fibrosis, who are chronically colonised with the organism Pseudomonas aeruginosa, often require multiple courses of intravenous aminoglycoside antibiotics for the management of pulmonary exacerbations. The properties of aminoglycosides - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Osteoporosis is a bone mineralisation disorder occurring in about one third of adults with cystic fibrosis. Bisphosphonates can increase bone mineral density and decrease the risk of new fractures in post-menopausal women and people receiving long-term or - Cochrane Database of Systematic Reviews
Cochrane Systematic Reviews,
Withdrawal is a necessary step prior to drug-free treatment or as the endpoint of long-term substitution treatment.
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