- Artemisinin-naphthoquine for treating uncomplicated Plasmodium falciparum malaria
Cochrane Systematic Reviews, 20-Feb-2015
The World Health Organization (WHO) recommends artemisinin-based combination therapy (ACT) for treating people with Plasmodium falciparum malaria. Five combinations are currently recommended, all administered over three days. Artemisinin-naphthoquine is a - Artesunate plus mefloquine versus mefloquine for treating uncomplicated malaria
Cochrane Systematic Reviews, 19-Oct-2005
Using a pilot system we have categorised this review as: “Historical question – no update intended: monotherapy no longer recommended" (see published notes). - Artesunate versus quinine for treating severe malaria
Cochrane Systematic Reviews, 13-Jun-2012
Severe malaria results in over a million deaths every year, most of them in children aged under five years and living in sub-Saharan Africa. This review examines whether treatment with artesunate, instead of the standard treatment quinine, would result in - Arthrocentesis and lavage for treating temporomandibular joint disorders
Cochrane Systematic Reviews, 16-Dec-2015
Temporomandibular joint disorders are important oral health problems, reducing the quality of life of sufferers. It has been estimated that approximately 20% to 30% of the adult population will experience temporomandibular joint dysfunction. Arthrocentesi - Arthrographic distension for adhesive capsulitis (frozen shoulder)
Cochrane Systematic Reviews, 21-Sep-2008
Adhesive capsulitis (frozen shoulder or painful stiff shoulder) is characterised by spontaneous onset of shoulder pain accompanied by progressive stiffness and disability. It is usually self-limiting but often has a prolonged course over two to three year - Arthroplasties (with and without bone cement) for proximal femoral fractures in adults
Cochrane Systematic Reviews, 11-May-2010
Numerous types of arthroplasties may be used in the surgical treatment of a hip fracture (proximal femoral fracture). The main differences between the implants are in the design of the stems, whether the stem is cemented or uncemented, whether a second ar - Arthroplasties for hip fracture in adults
Cochrane Systematic Reviews, 14-Feb-2022
Hip fractures are a major healthcare problem, presenting a huge challenge and burden to individuals and healthcare systems. The number of hip fractures globally is rising rapidly. The majority of hip fractures are treated surgically. This review evaluates - Arthroplasty versus fusion in single-level cervical degenerative disc disease
Cochrane Systematic Reviews, 28-Sep-2016
There is ongoing debate about whether fusion or arthroplasty is superior in the treatment of single level cervical degenerative disc disease. Mainly because the intended advantage of arthroplasty over fusion, that is, the prevention of symptoms due to adj - Arthroscopic debridement for knee osteoarthritis
Cochrane Systematic Reviews, 18-Sep-2008
Knee osteoarthritis (OA) is a progressive disease that initially affects the articular cartilage. Observational studies have shown benefits for arthroscopic debridement (AD) on the osteoarthritic knee, but other recent studies have yielded conflicting res - Arthroscopic surgery for degenerative knee disease (osteoarthritis including degenerative meniscal tears)
Cochrane Systematic Reviews, 3-Mar-2022
Arthroscopic knee surgery remains a common treatment for symptomatic knee osteoarthritis, including for degenerative meniscal tears, despite guidelines strongly recommending against its use. This Cochrane Review is an update of a non-Cochrane systematic r - Arthroscopy for temporomandibular disorders
Cochrane Systematic Reviews, 16-Dec-2015
Temporomandibular disorders (TMDs) are considered a collection of disorders involving many organic, psychological and psychosocial factors. They can involve the masticatory muscles or the temporomandibular joint (TMJ) and associated structures, or both. I - Artichoke leaf extract for treating hypercholesterolaemia
Cochrane Systematic Reviews, 19-May-2016
Hypercholesterolaemia is directly associated with an increased risk for coronary heart disease and other sequelae of atherosclerosis. Artichoke leaf extract (ALE) has been implicated in lowering cholesterol levels. Whether ALE is truly effective for this - Artificial and bioartificial support systems for liver failure
Cochrane Systematic Reviews, 26-Jan-2004
Artificial and bioartificial liver support systems may 'bridge' patients with acute or acute-on-chronic liver failure to liver transplantation or recovery. - Artificial corneas versus donor corneas for repeat corneal transplants
Cochrane Systematic Reviews, 13-May-2020
Individuals who have failed one or more full thickness penetrating keratoplasties may be offered repeat corneal surgery using an artificial or donor cornea. An artificial or prosthetic cornea is known as a keratoprosthesis. Both donor and artificial corne - 'As required' medication regimens for seriously mentally ill people in hospital
Cochrane Systematic Reviews, 21-Dec-2015
Drugs used to treat psychotic illnesses may take weeks to be effective. In the interim, additional 'as required' doses of medication can be used to calm patients in psychiatric wards. The practice is widespread, with 20% to 50% of people on acute psychiat - As required versus fixed schedule analgesic administration for postoperative pain in children
Cochrane Systematic Reviews, 26-Feb-2015
Acute postoperative pain occurs as a result of tissue damage following surgery. Administering the appropriate analgesia to children is a complex process and it is unclear whether children's postoperative pain is more successfully treated by using 'as requ - Ascorbic acid for the treatment of Charcot‐Marie‐Tooth disease
Cochrane Systematic Reviews, 11-Dec-2015
Charcot-Marie-Tooth disease (CMT) comprises a large group of different forms of hereditary motor and sensory neuropathy. The molecular basis of several CMT subtypes has been clarified during the last 20 years. Since slowly progressive muscle weakness and - Asenapine versus placebo for schizophrenia
Cochrane Systematic Reviews, 24-Nov-2015
Schizophrenia is a highly prevalent and chronic disorder that comprises a wide range of symptomatology. Asenapine is a recently developed atypical antipsychotic that is approved by the US Food and Drug Administration (FDA) for the treatment of schizophren - Aspiration and sclerotherapy versus hydrocoelectomy for treating hydrocoeles
Cochrane Systematic Reviews, 19-Nov-2014
Hydrocoeles are common cystic scrotal abnormalities, described as a fluid-filled collection between the visceral and parietal layers of the tunica vaginalis of the scrotum. There are two approaches for treatment of hydrocoeles: surgical open hydrocoelecto - Aspiration of the elbow joint for treating radial head fractures
Cochrane Systematic Reviews, 21-Nov-2014
Radial head fracture is the most common fracture of the elbow. It usually results from a fall onto an outstretched arm. In 1954, Mason classified these fractures into type 1 (undisplaced), type 2 (simple displaced), and type 3 (comminuted fractures). Aspi
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