- Use of hyaluronidase as an adjunct to local anaesthetic eye blocks to reduce intraoperative pain in adults
Cochrane Systematic Reviews, 2-Mar-2018
Hyaluronidase has been used over many decades as an adjunct to local anaesthetic solution to improve the speed of onset of eye blocks and to provide better akinesia and analgesia. With the evolution of modern eye surgery techniques, fast onset and akinesi - Use of plastic adhesive drapes during surgery for preventing surgical site infection
Cochrane Systematic Reviews, 22-Apr-2015
Surgical site infection has been estimated to occur in about 15% of clean surgery and 30% of contaminated surgery cases. Using plastic adhesive drapes to protect the wound from organisms that may be present on the surrounding skin during surgery is one st - Use of platelet transfusions prior to lumbar punctures or epidural anaesthesia for the prevention of complications in people with thrombocytopenia
Cochrane Systematic Reviews, 30-Apr-2018
People with a low platelet count (thrombocytopenia) often require lumbar punctures or an epidural anaesthetic. Lumbar punctures can be diagnostic (haematological malignancies, subarachnoid haematoma, meningitis) or therapeutic (spinal anaesthetic, adminis - Use of reflective materials during phototherapy for newborn infants with unconjugated hyperbilirubinaemia
Cochrane Systematic Reviews, 1-Jul-2020
Phototherapy is a well-established effective therapy for treating babies with significant neonatal jaundice. Studies have shown that increasing light intensity will increase its efficiency. A potentially inexpensive and easy way of increasing the intensit - User-held personalised information for routine care of people with severe mental illness
Cochrane Systematic Reviews, 30-Sep-2013
It is important to seek cost-effective methods of improving the care and outcome of those with serious mental illnesses. User-held records, where the person with the illness holds all or some personal information relating to the course and care of their i - Using alternative statistical formats for presenting risks and risk reductions
Cochrane Systematic Reviews, 9-Feb-2012
The success of evidence-based practice depends on the clear and effective communication of statistical information. - Uterine artery embolization for symptomatic uterine fibroids
Cochrane Systematic Reviews, 26-Dec-2014
Uterine fibroids cause heavy prolonged bleeding, pain, pressure symptoms and subfertility. The traditional method of treatment has been surgery as medical therapies have not proven effective. Uterine artery embolization has been reported to be an effectiv - Uterine distension media for outpatient hysteroscopy
Cochrane Systematic Reviews, 26-Nov-2021
Hysteroscopy done in an outpatient setting is the 'gold standard' method for evaluating the uterine cavity. Media used to distend the uterine cavity include gas as carbon dioxide and liquid as saline that can be used at room temperature or warmed to body - Uterine massage for preventing postpartum haemorrhage
Cochrane Systematic Reviews, 1-Jul-2013
Postpartum haemorrhage (PPH) (bleeding from the genital tract after childbirth) is a major cause of maternal mortality and disability, particularly in under-resourced areas. In these settings, uterotonics are often not accessible. There is a need for simp - Uterine muscle relaxant drugs for threatened miscarriage
Cochrane Systematic Reviews, 20-Jul-2005
Miscarriage is the spontaneous loss of a pregnancy before the fetus is viable. Uterine muscle relaxant drugs have been used for women at risk of miscarriage in the belief they relax uterine muscle, and hence reduce the risk of miscarriage. - Utero-placental Doppler ultrasound for improving pregnancy outcome
Cochrane Systematic Reviews, 19-Jul-2010
Impaired placentation can cause some of the most important obstetrical complications such as pre-eclampsia and intrauterine growth restriction and has been linked to increased fetal morbidity and mortality. The failure to undergo physiological trophoblast - Uterotonic agents for first‐line treatment of postpartum haemorrhage: a network meta‐analysis
Cochrane Systematic Reviews, 24-Nov-2020
Postpartum haemorrhage (PPH), defined as a blood loss of 500 mL or more after birth, is the leading cause of maternal death worldwide. The World Health Organization (WHO) recommends that all women giving birth should receive a prophylactic uterotonic agen - Uterotonic agents for preventing postpartum haemorrhage: a network meta‐analysis
Cochrane Systematic Reviews, 19-Dec-2018
Postpartum haemorrhage (PPH) is the leading cause of maternal mortality worldwide. Prophylactic uterotonic agents can prevent PPH, and are routinely recommended. The current World Health Organization (WHO) recommendation for preventing PPH is 10 IU (inter - Vaccination for preventing postherpetic neuralgia
Cochrane Systematic Reviews, 2-Mar-2011
Herpes zoster virus vaccine was recommended for the prevention of herpes zoster and its sequelae by the Advisory Committee on Immunization Practices (ACIP) in 2006. To date the efficacy and safety of vaccination for preventing the most common complication - Vaccines for measles, mumps, rubella, and varicella in children
Cochrane Systematic Reviews, 22-Nov-2021
Measles, mumps, rubella, and varicella (chickenpox) are serious diseases that can lead to serious complications, disability, and death. However, public debate over the safety of the trivalent MMR vaccine and the resultant drop in vaccination coverage in s - Vaccines for post‐exposure prophylaxis against varicella (chickenpox) in children and adults
Cochrane Systematic Reviews, 23-Jun-2014
The prevention of varicella (chickenpox) using live attenuated varicella vaccines has been demonstrated both in randomised controlled trials (RCTs) and in population-based immunisation programmes in countries such as the United States and Australia. Many - Vaccines for preventing anthrax
Cochrane Systematic Reviews, 15-Apr-2009
Anthrax is a bacterial zoonosis that occasionally causes human disease and is potentially fatal. Anthrax vaccines include a live-attenuated vaccine, an alum-precipitated cell-free filtrate vaccine, and a recombinant protein vaccine. - Vaccines for preventing anthrax
Cochrane Systematic Reviews, 9-Nov-2009
Anthrax is a potentially fatal bacterial disease with cutaneous, inhalation, and gastrointestinal forms. Three anthrax vaccines are commercially available, but their comparative effectiveness and safety is not clear. - Vaccines for preventing cholera: killed whole cell or other subunit vaccines (injected)
Cochrane Systematic Reviews, 8-Aug-2010
Injected cholera vaccines are rarely used today, although they may have some benefit. It is valuable to summarize the evidence for effectiveness of injected cholera vaccines for comparison with newer oral vaccines (subject of a separate Cochrane Review). - Vaccines for preventing enterotoxigenic Escherichia coli (ETEC) diarrhoea
Cochrane Systematic Reviews, 28-Jun-2013
Infection with enterotoxigenic Escherichia coli (ETEC) bacteria is a common cause of diarrhoea in adults and children in developing countries and is a major cause of 'travellers' diarrhoea' in people visiting or returning from endemic regions. A killed wh
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