- Vaccines for preventing invasive salmonella infections in people with sickle cell disease
Cochrane Systematic Reviews, 5-Dec-2018
Salmonella infections are a common bacterial cause of invasive disease in people with sickle cell disease especially children, and are associated with high morbidity and mortality rates. Although available in some centres, people with sickle cell anaemia - Vaccines for preventing Japanese encephalitis
Cochrane Systematic Reviews, 10-Nov-2008
Vaccination is recognized as the only practical measure for preventing Japanese encephalitis. Production shortage, costs, and issues of licensure impair vaccination programmes in many affected countries. Concerns over vaccine effectiveness and safety also - Vaccines for preventing malaria
Cochrane Systematic Reviews, 27-Nov-2019
Four types of malaria vaccine, SPf66 and MSP/RESA vaccines (against the asexual stages of the Plasmodium parasite) and CS-NANP and RTS,S vaccines (against the sporozoite stages), have been tested in randomized controlled trials in endemic areas. - Vaccines for preventing malaria (blood‐stage)
Cochrane Systematic Reviews, 18-Oct-2006
A malaria vaccine is needed because of the heavy burden of mortality and morbidity due to this disease. This review describes the results of trials of blood (asexual)-stage vaccines. Several are under development, but only one (MSP/RESA, also known as Com - Vaccines for preventing malaria (pre‐erythrocytic)
Cochrane Systematic Reviews, 18-Oct-2006
Vaccines against all stages of the malaria parasite are in development, mainly for Plasmodium falciparum, which causes the most serious form of malaria. Pre-erythrocytic vaccines act to prevent or delay a malaria attack by attacking the sporozoite and liv - Vaccines for preventing malaria (SPf66)
Cochrane Systematic Reviews, 19-Apr-2006
A malaria vaccine is badly needed. SPf66 was one of the earliest vaccines developed. It is a synthetic peptide vaccine containing antigens from the blood stages of malaria linked together with an antigen from the sporozoite stage, and is targeted mainly a - Vaccines for preventing plague
Cochrane Systematic Reviews, 26-Jan-1998
Plague is endemic in China, Mongolia, Burma, Vietnam, Indonesia, India, large parts of Southern Africa, the United States and South America. There are three types of vaccines (live attenuated, killed and F1 fraction) with varying means of administration. - Vaccines for preventing pneumococcal infection in adults
Cochrane Systematic Reviews, 31-Jan-2013
Diseases caused by Streptococcus pneumoniae (S. pneumoniae) continue to cause substantial morbidity and mortality globally. Whilst pneumococcal polysaccharide vaccines (PPVs) have the potential to prevent disease and death, the degree of protection afford - Vaccines for preventing rotavirus diarrhoea: vaccines in use
Cochrane Systematic Reviews, 17-Nov-2021
Rotavirus is a common cause of diarrhoea, diarrhoea-related hospital admissions, and diarrhoea-related deaths worldwide. Rotavirus vaccines prequalified by the World Health Organization (WHO) include Rotarix (GlaxoSmithKline), RotaTeq (Merck), and, more r - Vaccines for preventing smallpox
Cochrane Systematic Reviews, 18-Jul-2007
Smallpox was eradicated by 1980, but its possible use as a bioweapon has rekindled interest in the development of protective vaccines. Therefore, stockpiled calf lymph-derived vaccines and recently developed cell-cultured vaccines have been investigated t - Vaccines for preventing tick‐borne encephalitis
Cochrane Systematic Reviews, 21-Jan-2009
Tick-borne encephalitis (TBE) is a disease of the central nervous system caused by a tick-borne viral infection. TBE can lead to severe neurological syndromes such as meningitis, meningoencephalitis, and meningoencephalomyelitis, which can result in death - Vaccines for preventing typhoid fever
Cochrane Systematic Reviews, 31-May-2018
Typhoid fever and paratyphoid fever continue to be important causes of illness and death, particularly among children and adolescents in south-central and southeast Asia. Two typhoid vaccines are widely available, Ty21a (oral) and Vi polysaccharide (paren - Vaccines for prophylaxis of viral infections in patients with hematological malignancies
Cochrane Systematic Reviews, 26-Jan-2011
Viral infections cause significant morbidity and mortality in patients with hematological malignancies. It remains uncertain whether viral vaccinations in these patients are supported by good evidence. - Vaccines for the common cold
Cochrane Systematic Reviews, 18-May-2017
The common cold is a spontaneously remitting infection of the upper respiratory tract, characterised by a runny nose, nasal congestion, sneezing, cough, malaise, sore throat, and fever (usually < 37.8º C). The widespread morbidity caused by the common col - Vaccines for women for preventing neonatal tetanus
Cochrane Systematic Reviews, 6-Jul-2015
Tetanus is an acute, often fatal, disease caused by an exotoxin produced by Clostridium tetani. It occurs in newborn infants born to mothers who do not have sufficient circulating antibodies to protect the infant passively, by transplacental transfer. Pre - Vaginal chlorhexidine during labour for preventing maternal and neonatal infections (excluding Group B Streptococcal and HIV)
Cochrane Systematic Reviews, 14-Sep-2014
The incidence of chorioamnionitis occurs in between eight and 12 women for every 1000 live births and 96% of cases of chorioamnionitis are due to ascending infection. Following spontaneous vaginal delivery, 1% to 4% of women develop postpartum endometriti - Vaginal chlorhexidine during labour to prevent early-onset neonatal group B streptococcal infection
Cochrane Systematic Reviews, 4-Dec-2014
Although early-onset group B ß-hemolytic streptococcus (GBS) infection is rare, it accounts for approximately 30% of neonatal infections, has a high mortality rate, and is acquired through vertical transmission from colonized mothers. Several trials have - Vaginal dilator therapy for women receiving pelvic radiotherapy
Cochrane Systematic Reviews, 8-Sep-2014
Vaginal dilation therapy is advocated after pelvic radiotherapy to prevent stenosis (abnormal narrowing of the vagina), but can be uncomfortable and psychologically distressing. - Vaginal disinfection for preventing mother‐to‐child transmission of HIV infection
Cochrane Systematic Reviews, 19-Oct-2005
Mother-to-child transmission (MTCT) of HIV infection is one of the most tragic consequences of the HIV epidemic, especially in resource-limited countries, resulting in about 650 000 new paediatric HIV infections each year worldwide. The paediatric HIV epi - Vaginal misoprostol for cervical ripening and induction of labour
Cochrane Systematic Reviews, 6-Oct-2010
Misoprostol (Cytotec, Searle) is a prostaglandin E1 analogue widely used for off-label indications such as induction of abortion and of labour. This is one of a series of reviews of methods of cervical ripening and labour induction using standardised meth
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