- Trihexyphenidyl for dystonia in cerebral palsy
Cochrane Systematic Reviews, 15-May-2018
Cerebral palsy occurs in up to 2.1 of every 1000 live births and encompasses a range of motor problems and movement disorders. One commonly occurring movement disorder amongst those with cerebral palsy is dystonia: sustained or intermittent involuntary mu - Trimetazidine for stable angina
Cochrane Systematic Reviews, 20-Mar-2017
Patients with stable angina not controlled by monotherapy with nitrates, beta blockers, or calcium channel blockers are often treated with combinations of these drugs. There may be adverse effects from, or contraindications to, the use of combinations. In - Triphasic versus monophasic oral contraceptives for contraception
Cochrane Systematic Reviews, 9-Nov-2011
Side effects of oral contraceptive (OC) pills discourage adherence to and continuation of OC regimens. Strategies to decrease adverse effects led to the introduction of the triphasic OC in the 1980s. Whether triphasic OCs have higher accidental pregnancy - Triptans for acute cluster headache
Cochrane Systematic Reviews, 17-Jul-2013
This is an updated version of the original Cochrane review published in Issue 4, 2010 (Law 2010). Cluster headache is an uncommon, severely painful, and disabling condition, with rapid onset. Validated treatment options are limited; first-line therapy inc - Tripterygium wilfordii Hook F (a traditional Chinese medicine) for primary nephrotic syndrome
Cochrane Systematic Reviews, 11-Aug-2013
Tripterygium wilfordii Hook F (TwHF), a traditional Chinese herbal medicine used as an immunosuppressive agent, has been prescribed in China for patients with primary nephrotic syndrome (NS) for more than two decades. Although patients with primary NS in - Trocar types in laparoscopy
Cochrane Systematic Reviews, 8-Dec-2015
Laparoscopic surgery has led to great clinical improvements in many fields of surgery; however, it requires the use of trocars, which may lead to complications as well as postoperative pain. The complications include intra-abdominal vascular and visceral - Troleandomycin as an oral corticosteroid sparing agent in stable asthma
Cochrane Systematic Reviews, 23-Oct-2000
Patients with chronic severe asthma are often dependent on the long term prescription of oral corticosteroids. The use of steroids is associated with serious side effects. Physicians treating such patients continue to search for alternative therapies that - Trypanocidal drugs for chronic asymptomatic Trypanosoma cruzi infection
Cochrane Systematic Reviews, 27-May-2014
Prevention of chronic chagasic cardiomyopathy (CCC) by treating infected populations with trypanocidal therapy (TT) remains a challenge. Despite a renewed enthusiasm for TT, uncertainty regarding its efficacy, concerns about its safety and limited availab - Trypanocidal drugs for late‐stage, symptomatic Chagas disease (Trypanosoma cruzi infection)
Cochrane Systematic Reviews, 11-Dec-2020
People with Chagas disease may develop progressive and lethal heart conditions. Drugs to eliminate the parasite Trypanosoma cruzi (T cruzi) currently carry limited therapeutic value and are used in the early stages of the disease. Extending the use of the - Tryptophan and 5‐Hydroxytryptophan for depression
Cochrane Systematic Reviews, 21-Jan-2002
5 Hydroxytryptophan (5-HTP) and tryptophan are so-called natural alternatives to traditional antidepressants, used to treat unipolar depression and dysthymia. - T-tube drainage versus primary closure after laparoscopic common bile duct exploration
Cochrane Systematic Reviews, 18-Jun-2013
T-tube drainage may prevent bile leak from the biliary tract following bile duct exploration and it offers post-operative access to the bile ducts for visualisation and exploration. Use of T-tube drainage after laparoscopic common bile duct (CBD) explorat - T-tube drainage versus primary closure after open common bile duct exploration
Cochrane Systematic Reviews, 18-Jun-2013
Between 5% and 11% of people undergoing cholecystectomy have common bile duct stones. Stones may be removed at the time of cholecystectomy by opening and clearing the common bile duct. The optimal technique is unclear. - Tubal flushing for subfertility
Cochrane Systematic Reviews, 15-Oct-2020
Establishing the subgroup analysis of the fallopian tubes (tubes) is a commonly undertaken diagnostic investigation for women with subfertility. This is usually achieved by flushing contrast medium through the tubes and visualising patency on radiographs, - Tumor necrosis factor‐alpha antibody for induction of remission in Crohn's disease
Cochrane Systematic Reviews, 20-Oct-2003
Crohn's disease may be refractory to conventional treatments such as corticosteroids, enteral nutrition and immuno-suppressive agents. A number of patients with the disease may also become steroid-dependent leading to increased risk of developing steroid- - Tumor necrosis factor‐alpha antibody for maintenance of remission in Crohn's disease
Cochrane Systematic Reviews, 23-Jan-2008
Crohn's disease may be refractory to conventional treatments including corticosteroids and immunosuppressives. Recent studies suggest TNF-a blocking agents may be effective in maintaining remission in Crohn's disease. - Tumour bed boost radiotherapy for women after breast‐conserving surgery
Cochrane Systematic Reviews, 6-Nov-2017
Breast-conserving therapy, involving breast-conserving surgery followed by whole-breast irradiation and optionally a boost to the tumour bed, is a standard therapeutic option for women with early-stage breast cancer. A boost to the tumour bed means that a - Tumour necrosis factor alpha blocking agents for induction of remission in ulcerative colitis
Cochrane Systematic Reviews, 19-Jul-2009
Anti-TNF-a agents have been shown to be effective for the induction of remission in Crohn's disease. The role of TNF-a blocking agents in ulcerative colitis is, however, unclear and recent studies have yielded conflicting results. - Twenty‐four hour care for schizophrenia
Cochrane Systematic Reviews, 15-Apr-2009
Despite modern treatment approaches and a focus on community care, there remains a group of people who cannot easily be discharged from psychiatric hospital directly into the community. Twenty-four hour residential rehabilitation (a 'ward-in-a-house') is - Type I interferons for induction of remission in ulcerative colitis
Cochrane Systematic Reviews, 14-Sep-2015
Interferons (IFNs) are cytokines which possess immunoregulatory properties and have been used to successfully treat a number of chronic inflammatory disorders. It has been postulated that Type I IFNs may be able to re-establish the Th1/Th2 balance in Th2 - Type II or type III radical hysterectomy compared to chemoradiotherapy as a primary intervention for stage IB2 cervical cancer
Cochrane Systematic Reviews, 12-Oct-2018
Cervical cancer is the fourth most common cancer in women, with 528,000 estimated new cases globally in 2012. A large majority (around 85%) of the disease burden occurs in low- and middle-income countries (LMICs), where it accounts for almost 12% of all f
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