- Treatment of obstructive sleep apnoea for chronic cough in children
Cochrane Systematic Reviews, 7-Mar-2011
Childhood obstructive sleep apnoea (OSA) is a disorder that is characterised by repeated episodes of partial or complete upper airway obstruction (UAO) during sleep that result in disruption of normal ventilation and sleep patterns. Chronic cough in child - Treatment of periodontitis for glycaemic control in people with diabetes mellitus
Cochrane Systematic Reviews, 14-Apr-2022
Glycaemic control is a key component in diabetes mellitus (diabetes) management. Periodontitis is the inflammation and destruction of the underlying supporting tissues of the teeth. Some studies have suggested a bidirectional relationship between glycaemi - Treatment of seizures in multiple sclerosis
Cochrane Systematic Reviews, 8-Jul-2009
Epileptic seizures occur in only a minority of patients with multiple sclerosis (MS), but can have serious consequences. The available literature suggests an association of seizures in MS with cortical and subcortical demyelinating lesions, which suggest - Treatment of severe or progressive Kaposi's sarcoma in HIV-infected adults
Cochrane Systematic Reviews, 29-Aug-2014
Kaposi's sarcoma remains the most common cancer in Sub-Saharan Africa and the second most common cancer in HIV-infected patients worldwide. Since the introduction of highly active antiretroviral therapy (HAART), there has been a decline in its incidence. - Treatment of vaginal bleeding irregularities induced by progestin only contraceptives
Cochrane Systematic Reviews, 16-Oct-2013
Despite their high effectiveness, progestin-only contraceptives are considered less than ideal by the many women who experience irregular vaginal bleeding when using them. Current treatments to control these bleeding problems are not sufficiently effectiv - Treatment of valvular heart disease during pregnancy for improving maternal and neonatal outcome
Cochrane Systematic Reviews, 3-Apr-2011
Valvular heart disease constitutes the majority of all causes of heart disease in pregnancy. In the presence of valvular heart disease, the necessary haemodynamic changes of pregnancy might cause heart failure, leading to severe maternal and fetal morbidi - Treatment options for progression or recurrence of glioblastoma: a network meta‐analysis
Cochrane Systematic Reviews, 5-Jan-2021
Glioblastoma (GBM) is a highly malignant brain tumour that almost inevitably progresses or recurs after first line standard of care. There is no consensus regarding the best treatment/s to offer people upon disease progression or recurrence. For the purpo - Treatment regimens for administration of anti‐vascular endothelial growth factor agents for neovascular age‐related macular degeneration
Cochrane Systematic Reviews, 5-May-2020
Age-related macular degeneration (AMD) is one of the leading causes of permanent blindness worldwide. The current mainstay of treatment for neovascular AMD (nAMD) is intravitreal injection of anti-vascular endothelial growth factor (anti-VEGF) agents: afl - Treatment with disease-modifying drugs for people with a first clinical attack suggestive of multiple sclerosis
Cochrane Systematic Reviews, 25-Apr-2017
The treatment of multiple sclerosis has changed over the last 20 years. The advent of disease-modifying drugs in the mid-1990s heralded a period of rapid progress in the understanding and management of multiple sclerosis. With the support of magnetic reso - Treatments for adults with prominent lower front teeth
Cochrane Systematic Reviews, 23-May-2018
Prominent lower front teeth may be associated with a large or prognathic lower jaw (mandible) or a small or retrusive upper jaw (maxilla). Edward Angle, who may be considered the father of modern orthodontics, classified the malocclusion in this situation - Treatments for breast abscesses in breastfeeding women
Cochrane Systematic Reviews, 17-Aug-2015
The benefits of breastfeeding are well known, and the World Health Organization recommends exclusive breastfeeding for the first six months of life and continuing breastfeeding to age two. However, many women stop breastfeeding due to lactational breast a - Treatments for breast engorgement during lactation
Cochrane Systematic Reviews, 18-Sep-2020
Engorgement is the overfilling of breasts with milk, often occurring in the early days postpartum. It results in swollen, hard, painful breasts and may lead to premature cessation of breastfeeding, decreased milk production, cracked nipples and mastitis. - Treatments for breast engorgement during lactation
Cochrane Systematic Reviews, 28-Jul-2010
National surveys have shown that painful breasts are the second most common reason for giving up breastfeeding in the first two weeks after birth in the UK. One factor contributing to such pain can be breast engorgement. Views differ as to how engorgement - Treatments for chronic inflammatory demyelinating polyradiculoneuropathy (CIDP): an overview of systematic reviews
Cochrane Systematic Reviews, 13-Jan-2017
Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is a chronic progressive or relapsing and remitting disease that usually causes weakness and sensory loss. The symptoms are due to autoimmune inflammation of peripheral nerves. CIPD affects - Treatments for delusional disorder
Cochrane Systematic Reviews, 22-May-2015
Delusional disorder is commonly considered to be difficult to treat. Antipsychotic medications are frequently used and there is growing interest in a potential role for psychological therapies such as cognitive behavioural therapy (CBT) in the treatment o - Treatments for gestational diabetes
Cochrane Systematic Reviews, 8-Jul-2009
Gestational diabetes (GDM) affects 3% to 6% of all pregnancies. Women are often intensively managed with increased obstetric monitoring, dietary regulation, and insulin. However, there has been no sound evidence base to support intensive treatment. The ke - Treatments for iron‐deficiency anaemia in pregnancy
Cochrane Systematic Reviews, 5-Oct-2011
Iron deficiency, the most common cause of anaemia in pregnancy worldwide, can be mild, moderate or severe. Severe anaemia can have very serious consequences for mothers and babies, but there is controversy about whether treating mild or moderate anaemia p - Treatments for preventing recurrence of infection with Pseudomonas aeruginosa in people with cystic fibrosis
Cochrane Systematic Reviews, 17-Dec-2019
Chronic infection with Pseudomonas aeruginosa (PA) in cystic fibrosis (CF) is a source of much morbidity and mortality. Eradication of early PA infection is possible, but can recur in many individuals. We sought to examine strategies to delay the time to - Treatments for priapism in boys and men with sickle cell disease
Cochrane Systematic Reviews, 6-Apr-2020
Sickle cell disease comprises a group of genetic haemoglobin disorders. The predominant symptom associated with sickle cell disease is pain resulting from the occlusion of small blood vessels by abnormally 'sickle-shaped' red blood cells. There are other - Treatments for primary delusional infestation
Cochrane Systematic Reviews, 10-Dec-2019
Primary delusional infestation (DI) is a primary psychiatric disorder characterised by delusions and abnormal tactile sensations. The pathophysiology is undecided and treatment includes both pharmacological and non-pharmacological options. There is curren
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