- Troleandomycin as an oral corticosteroid sparing agent in stable asthma
Cochrane Systematic Reviews, 23-Oct-2000
Patients with chronic severe asthma are often dependent on the long term prescription of oral corticosteroids. The use of steroids is associated with serious side effects. Physicians treating such patients continue to search for alternative therapies that - Trypanocidal drugs for chronic asymptomatic Trypanosoma cruzi infection
Cochrane Systematic Reviews, 27-May-2014
Prevention of chronic chagasic cardiomyopathy (CCC) by treating infected populations with trypanocidal therapy (TT) remains a challenge. Despite a renewed enthusiasm for TT, uncertainty regarding its efficacy, concerns about its safety and limited availab - Trypanocidal drugs for late‐stage, symptomatic Chagas disease (Trypanosoma cruzi infection)
Cochrane Systematic Reviews, 11-Dec-2020
People with Chagas disease may develop progressive and lethal heart conditions. Drugs to eliminate the parasite Trypanosoma cruzi (T cruzi) currently carry limited therapeutic value and are used in the early stages of the disease. Extending the use of the - Tryptophan and 5‐Hydroxytryptophan for depression
Cochrane Systematic Reviews, 21-Jan-2002
5 Hydroxytryptophan (5-HTP) and tryptophan are so-called natural alternatives to traditional antidepressants, used to treat unipolar depression and dysthymia. - T-tube drainage versus primary closure after laparoscopic common bile duct exploration
Cochrane Systematic Reviews, 18-Jun-2013
T-tube drainage may prevent bile leak from the biliary tract following bile duct exploration and it offers post-operative access to the bile ducts for visualisation and exploration. Use of T-tube drainage after laparoscopic common bile duct (CBD) explorat - T-tube drainage versus primary closure after open common bile duct exploration
Cochrane Systematic Reviews, 18-Jun-2013
Between 5% and 11% of people undergoing cholecystectomy have common bile duct stones. Stones may be removed at the time of cholecystectomy by opening and clearing the common bile duct. The optimal technique is unclear. - Tubal flushing for subfertility
Cochrane Systematic Reviews, 15-Oct-2020
Establishing the subgroup analysis of the fallopian tubes (tubes) is a commonly undertaken diagnostic investigation for women with subfertility. This is usually achieved by flushing contrast medium through the tubes and visualising patency on radiographs, - Tumor necrosis factor‐alpha antibody for induction of remission in Crohn's disease
Cochrane Systematic Reviews, 20-Oct-2003
Crohn's disease may be refractory to conventional treatments such as corticosteroids, enteral nutrition and immuno-suppressive agents. A number of patients with the disease may also become steroid-dependent leading to increased risk of developing steroid- - Tumor necrosis factor‐alpha antibody for maintenance of remission in Crohn's disease
Cochrane Systematic Reviews, 23-Jan-2008
Crohn's disease may be refractory to conventional treatments including corticosteroids and immunosuppressives. Recent studies suggest TNF-a blocking agents may be effective in maintaining remission in Crohn's disease. - Tumour bed boost radiotherapy for women after breast‐conserving surgery
Cochrane Systematic Reviews, 6-Nov-2017
Breast-conserving therapy, involving breast-conserving surgery followed by whole-breast irradiation and optionally a boost to the tumour bed, is a standard therapeutic option for women with early-stage breast cancer. A boost to the tumour bed means that a - Tumour necrosis factor alpha blocking agents for induction of remission in ulcerative colitis
Cochrane Systematic Reviews, 19-Jul-2009
Anti-TNF-a agents have been shown to be effective for the induction of remission in Crohn's disease. The role of TNF-a blocking agents in ulcerative colitis is, however, unclear and recent studies have yielded conflicting results. - Twenty‐four hour care for schizophrenia
Cochrane Systematic Reviews, 15-Apr-2009
Despite modern treatment approaches and a focus on community care, there remains a group of people who cannot easily be discharged from psychiatric hospital directly into the community. Twenty-four hour residential rehabilitation (a 'ward-in-a-house') is - Type I interferons for induction of remission in ulcerative colitis
Cochrane Systematic Reviews, 14-Sep-2015
Interferons (IFNs) are cytokines which possess immunoregulatory properties and have been used to successfully treat a number of chronic inflammatory disorders. It has been postulated that Type I IFNs may be able to re-establish the Th1/Th2 balance in Th2 - Type II or type III radical hysterectomy compared to chemoradiotherapy as a primary intervention for stage IB2 cervical cancer
Cochrane Systematic Reviews, 12-Oct-2018
Cervical cancer is the fourth most common cancer in women, with 528,000 estimated new cases globally in 2012. A large majority (around 85%) of the disease burden occurs in low- and middle-income countries (LMICs), where it accounts for almost 12% of all f - Type of incision for below knee amputation
Cochrane Systematic Reviews, 8-Apr-2014
Below knee amputation (BKA) may be necessary in patients with advanced critical limb ischaemia or diabetic foot sepsis in whom no other treatment option is available. There is no consensus as to which surgical technique achieves the maximum rehabilitation - Types of indwelling urethral catheters for short-term catheterisation in hospitalised adults
Cochrane Systematic Reviews, 15-Sep-2014
Urinary tract infection (UTI) is the most common hospital-acquired infection. The major associated cause is indwelling urethral catheters. Several measures have been introduced to reduce catheter-associated urinary tract infections (CAUTIs). One of these - Types of indwelling urinary catheters for long‐term bladder drainage in adults
Cochrane Systematic Reviews, 17-Oct-2012
Prolonged urinary catheterization is common amongst people in long-term care settings and this carries a high risk of developing a catheter-related urinary tract infection and associated complications. A variety of different kinds of urethral catheters ar - Types of intra-muscular opioids for maternal pain relief in labour
Cochrane Systematic Reviews, 26-Oct-2008
Pethidine is the most widely used intra-muscular opioid for the relief of labour pain. However concerns have been raised about its effectiveness and the possibility of depressing respiration in newborns. - Types of intraocular lenses for cataract surgery in eyes with uveitis
Cochrane Systematic Reviews, 28-Feb-2014
Cataract formation often occurs in people with uveitis. It is unclear which intraocular lens (IOL) type is optimal for use in cataract surgery for eyes with uveitis. - Types of materials for frontalis sling surgery for congenital ptosis
Cochrane Systematic Reviews, 23-Apr-2019
Congenital ptosis is a drooping of one or both eyelids at birth, often due to poor development of the levator palpebrae superioris muscle. This can result in amblyopia, astigmatism, and ocular torticollis and therefore may necessitate surgical interventio
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