- Vitamin D supplementation for prevention of mortality in adults
Cochrane Systematic Reviews, 5-Dec-2013
Available evidence on the effects of vitamin D on mortality has been inconclusive. In a recent systematic review, we found evidence that vitamin D3 may decrease mortality in mostly elderly women. The present systematic review updates and reassesses the be - Vitamin D supplementation for sickle cell disease
Cochrane Systematic Reviews,
Sickle cell disease (SCD) is a genetic chronic haemolytic and pro-inflammatory disorder. With increased catabolism and deficits in energy and nutrient intake, individuals with SCD suffer multiple macro- and micro-nutritional deficiencies, including vitami - Vitamin D supplementation for term breastfed infants to prevent vitamin D deficiency and improve bone health
Cochrane Systematic Reviews,
Vitamin D deficiency is common worldwide, contributing to nutritional rickets and osteomalacia which have a major impact on health, growth, and development of infants, children and adolescents. Vitamin D levels are low in breast milk and exclusively breas - Vitamin D supplementation for women during pregnancy
Cochrane Systematic Reviews, 26-Jul-2019
Vitamin D supplementation during pregnancy may be needed to protect against adverse pregnancy outcomes. This is an update of a review that was first published in 2012 and then in 2016. - Vitamin D, calcium or a combination of vitamin D and calcium for the treatment of nutritional rickets in children
Cochrane Systematic Reviews, 15-Apr-2020
Nutritional rickets is a disease which affects children, especially in low- and middle-income countries. It causes problems such as skeletal deformities and impaired growth. The most common cause of nutritional rickets is vitamin D deficiency. Vitamin D a - Vitamin E for Alzheimer's dementia and mild cognitive impairment
Cochrane Systematic Reviews, 7-Apr-2017
Vitamin E occurs naturally in the diet. It has several biological activities, including functioning as an antioxidant to scavenge toxic free radicals. Evidence that free radicals may contribute to the pathological processes behind cognitive impairment has - Vitamin E for antipsychotic‐induced tardive dyskinesia
Cochrane Systematic Reviews, 24-Sep-2019
Antipsychotic (neuroleptic) medication is used extensively to treat people with chronic mental illnesses. Its use, however, is associated with adverse effects, including movement disorders such as tardive dyskinesia (TD) – a problem often seen as repetiti - Vitamin E for intermittent claudication
Cochrane Systematic Reviews, 16-Oct-2008
It is thought that vitamin E may improve tolerance to intermittent claudication (i.e. pain caused by ischaemia in the muscles of the leg during exercise), thereby relieving the pain, through a variety of mechanisms. - Vitamin E supplementation for prevention of morbidity and mortality in preterm infants
Cochrane Systematic Reviews, 12-Aug-2008
Treating very low birth weight (VLBW) infants with pharmacologic doses of vitamin E as an antioxidant agent has been proposed for preventing or limiting retinopathy of prematurity, intracranial hemorrhage, hemolytic anemia, and chronic lung disease. Howev - Vitamin E supplementation in people with cystic fibrosis
Cochrane Systematic Reviews,
People with cystic fibrosis are at an increased risk of fat-soluble vitamin deficiency, including vitamin E. Vitamin E deficiency can cause a host of conditions such as haemolytic anaemia, cerebellar ataxia and cognitive difficulties. Vitamin E supplement - Vitamin E supplementation in pregnancy
Cochrane Systematic Reviews, 22-Mar-2016
Vitamin E supplementation may help reduce the risk of pregnancy complications involving oxidative stress, such as pre-eclampsia. There is a need to evaluate the efficacy and safety of vitamin E supplementation in pregnancy. - Vitamin K antagonists versus antiplatelet therapy after transient ischaemic attack or minor ischaemic stroke of presumed arterial origin
Cochrane Systematic Reviews, 14-Jan-2013
People who have had a transient ischaemic attack (TIA) or non-disabling ischaemic stroke have an annual risk of major vascular events of between 4% and 11%. Aspirin reduces this risk by 20% at most. Secondary prevention trials after myocardial infarction - Vitamin K antagonists versus low‐molecular‐weight heparin for the long term treatment of symptomatic venous thromboembolism
Cochrane Systematic Reviews, 24-Jul-2017
People with venous thromboembolism (VTE) generally are treated for five days with intravenous unfractionated heparin or subcutaneous low-molecular-weight heparin (LMWH), followed by three months of vitamin K antagonists (VKAs). Treatment with VKAs require - Vitamin K for improved anticoagulation control in patients receiving warfarin
Cochrane Systematic Reviews, 15-May-2014
Effective use of warfarin involves keeping the international normalised ratio (INR) within a relatively narrow therapeutic range. However, patients respond widely to their dose of warfarin. Overcoagulation can lead to an increased risk of excessive bleedi - Vitamin K for the primary prevention of cardiovascular disease
Cochrane Systematic Reviews, 21-Sep-2015
A deficiency in vitamin K has been associated with increased calcium deposition and coronary artery calcification, which may lead to cardiovascular disease. - Vitamin K for upper gastrointestinal bleeding in people with acute or chronic liver diseases
Cochrane Systematic Reviews, 8-Jun-2015
Upper gastrointestinal bleeding is one of the most frequent causes of morbidity and mortality in the course of liver cirrhosis. Several treatments are used for upper gastrointestinal bleeding in people with liver diseases. One of them is vitamin K adminis - Vitamin K prior to preterm birth for preventing neonatal periventricular haemorrhage
Cochrane Systematic Reviews, 15-Feb-2011
Preterm infants are at risk of periventricular haemorrhage (PVH). This can be a sign of brain damage that might lead to neurodevelopmental abnormalities, including cerebral palsy. It has been suggested that vitamin K might improve coagulation in preterm i - Vitamin K supplementation for cystic fibrosis
Cochrane Systematic Reviews,
Malabsorption and deficiency of fat-soluble vitamins K may occur in cystic fibrosis, a genetic disorder affecting multiple organs. Vitamin K is known to play an important role in both blood coagulation and bone formation, hence the role of supplementation - Vitamin supplementation for preventing miscarriage
Cochrane Systematic Reviews, 5-May-2016
Miscarriage is a common complication of pregnancy that can be caused by a wide range of factors. Poor dietary intake of vitamins has been associated with an increased risk of miscarriage, therefore supplementing women with vitamins either prior to or in e - Vitamins C and E for asthma and exercise‐induced bronchoconstriction
Cochrane Systematic Reviews, 12-Jun-2018
The association between dietary antioxidants and asthma or exercise-induced bronchoconstriction (EIB) is not fully understood. Vitamin C and vitamin E are natural antioxidants that are predominantly present in fruits and vegetables; inadequate vitamin E i
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