- Topical interventions for genital lichen sclerosus
Cochrane Systematic Reviews, 7-Dec-2011
Lichen sclerosus is a chronic, inflammatory skin condition that most commonly occurs in adult women, although it may also be seen in men and children. It primarily affects the genital area and around the anus, where it causes persistent itching and sorene - Topical lidocaine for neuropathic pain in adults
Cochrane Systematic Reviews, 24-Jul-2014
Lidocaine is a local anaesthetic that is sometimes used on the skin to treat neuropathic pain. - Topical lidocaine for the treatment of postherpetic neuralgia
Cochrane Systematic Reviews, 10-Jun-2019
This is an update of the original Cochrane review published in Issue 2, 2007. The cause of postherpetic neuralgia is damage to peripheral neurons, dorsal root ganglia, and the dorsal horn of the spinal cord, secondary to herpes zoster infection (shingles) - Topical medication instillation techniques for glaucoma
Cochrane Systematic Reviews, 20-Feb-2017
Glaucoma is a leading cause of irreversible blindness worldwide and the second most common cause of blindness after cataracts. The primary treatment for glaucoma aims to lower intraocular pressure (IOP) with the use of topical medicines. Topical medicatio - Topical microbicides for preventing sexually transmitted infections
Cochrane Systematic Reviews, 13-Mar-2021
This is a updated version of our Cochrane Review published in Issue 6, 2012. Sexually-transmitted infections (STIs) continue to rise worldwide, imposing an enormous morbidity and mortality burden. Effective prevention strategies, including microbicides, a - Topical mydriatics as adjunctive therapy for traumatic iridocyclitis
Cochrane Systematic Reviews, 25-Aug-2020
Traumatic eye complaints account for 3% of all hospital emergency department visits. The most common traumatic injury to the eye is blunt trauma, which accounts for 30% of these visits. Blunt trauma frequently leads to traumatic iridocyclitis, thus causin - Topical nasal steroids for intermittent and persistent allergic rhinitis in children
Cochrane Systematic Reviews, 24-Jan-2007
Allergic rhinitis is a very common chronic illness affecting 10% to 40% of children worldwide. There has been a significant increase in prevalence among children over the last two decades and this increase has been accompanied by a parallel increase in co - Topical nasal steroids for treating nasal polyposis in people with cystic fibrosis
Cochrane Systematic Reviews, 22-Jun-2015
Nasal polyps frequently occur in people with cystic fibrosis. Sinus infections have been shown to be a factor in the development of serious chest complications in these people. Nasal polyps have been linked to a higher risk of lower respiratory tract infe - Topical negative pressure for treating chronic wounds
Cochrane Systematic Reviews, 9-Jun-2015
Chronic wounds mainly affect the elderly and those with multiple health problems. Despite the use of modern dressings, some of these wounds take a long time to heal, fail to heal, or recur, causing significant pain and discomfort to the person and cost to - Topical non-steroidal anti-inflammatory agents for diabetic cystoid macular oedema
Cochrane Systematic Reviews, 12-Feb-2015
Diabetic cystoid macular oedema (CMO) is a condition which involves fluid accumulation in the inner portion of the retina. It often follows changes in retinal blood vessels which enhance the fluid to come out of vessels. Although it may be asymptomatic, s - Topical non‐steroidal anti‐inflammatory drugs for analgesia in traumatic corneal abrasions
Cochrane Systematic Reviews, 18-May-2017
Traumatic corneal abrasions are relatively common and there is a lack of consensus about analgesia in their management. It is therefore important to document the clinical efficacy and safety profile of topical ophthalmic non-steroidal anti-inflammatory dr - Topical NSAIDs for acute musculoskeletal pain in adults
Cochrane Systematic Reviews, 15-Jun-2015
Use of topical NSAIDs to treat acute musculoskeletal conditions has become widely accepted because they can provide pain relief without associated systemic adverse events. This review is an update of 'Topical NSAIDs for acute pain in adults' originally pu - Topical NSAIDs for chronic musculoskeletal pain in adults
Cochrane Systematic Reviews, 22-Apr-2016
Use of topical nonsteroidal anti-inflammatory drugs (NSAIDs) to treat chronic musculoskeletal conditions has become widely accepted because they can provide pain relief without associated systemic adverse events. This review is an update of 'Topical NSAID - Topical pharmacologic interventions versus placebo for epidemic keratoconjunctivitis
Cochrane Systematic Reviews, 3-Mar-2022
Viruses cause about 80% of all cases of acute conjunctivitis. Human adenoviruses are believed to account for 65% to 90% of cases of viral conjunctivitis, or 20% to 75% of all causes of infectious keratoconjunctivitis worldwide. Epidemic keratoconjunctivit - Topical phenytoin for treating pressure ulcers
Cochrane Systematic Reviews, 22-Feb-2017
Pressure ulcers are common in clinical practice and pose a significant health problem worldwide. Apart from causing suffering to patients, they also result in longer hospital stays and increase the cost of health care. A variety of methods are used for tr - Topical pimecrolimus for eczema
Cochrane Systematic Reviews, 22-Mar-2009
Pimecrolimus was developed as an alternative to topical corticosteroids for treating eczema (atopic dermatitis) but its efficacy and safety compared with existing treatments remains unclear. - Topical preparations for preventing stretch marks in pregnancy
Cochrane Systematic Reviews, 5-Oct-2012
Striae gravidarum (stretch marks developing during pregnancy) occur in 50% to 90% of women. They appear as red or purple lines or streaks that fade slowly to leave pale lines or marks on the skin. The abdomen, breasts and thighs are commonly affected. The - Topical silver for preventing wound infection
Cochrane Systematic Reviews, 17-Mar-2010
Silver-containing treatments are popular and used in wound treatments to combat a broad spectrum of pathogens, but evidence of their effectiveness in preventing wound infection or promoting healing is lacking. - Topical silver for treating infected wounds
Cochrane Systematic Reviews, 6-Sep-2010
Topical silver treatments and silver dressings are increasingly used for the local treatment of contaminated or infected wounds, however, there is a lack of clarity regarding the evidence for their effectiveness. - Topical steroid for chronic rhinosinusitis without polyps
Cochrane Systematic Reviews, 25-Apr-2016
Topical corticosteroid is used as part of a comprehensive medical treatment for chronic rhinosinusitis (CRS) without polyps. Nevertheless, there is insufficient evidence to show a clear overall benefit. Trials studying the efficacy of topical corticostero
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