- Treatment discontinuation with selective serotonin reuptake inhibitors (SSRIs) versus tricyclic antidepressants (TCAs)
Cochrane Systematic Reviews, 31-Oct-2008
Selective serotonin reuptake inhibitors are thought to have better discontinuation rates (i.e. less people dropping out) than tricyclic and heterocyclic antidepressant drugs. It is important to quantify the drop-out rates of different antidepressant drugs - Treatment for amphetamine dependence and abuse
Cochrane Systematic Reviews, 15-Apr-2014
Amphetamine use is of concern because it causes a variety of devastating health physical and neurological consequences, including amphetamine-induced mental disorders. - Treatment for amphetamine psychosis
Cochrane Systematic Reviews, 21-Jan-2009
Chronic amphetamine users may have experience of paranoia and hallucination. It has long been believed that dopamine antagonists, such as chlorpromazine, haloperidol, and thioridazine, are effective for the treatment of amphetamine psychosis. - Treatment for amphetamine withdrawal
Cochrane Systematic Reviews, 15-Apr-2009
Few studies examined treatments for amphetamine withdrawal, although it is a common problem among amphetamine users. Its symptoms, in particular intense craving, may be a critical factor leading to relapse to amphetamine use. In clinical practice, medicat - Treatment for anemia in people with AIDS
Cochrane Systematic Reviews, 5-Oct-2011
Anemia is common in persons with HIV infection and is associated with poor prognosis. There is a need to assess the effects of anemia treatments, and to determine whether these interventions are beneficial. - Treatment for ascites in adults with decompensated liver cirrhosis: a network meta‐analysis
Cochrane Systematic Reviews, 16-Jan-2020
Approximately 20% of people with cirrhosis develop ascites. Several different treatments are available; including, among others, paracentesis plus fluid replacement, transjugular intrahepatic portosystemic shunts, aldosterone antagonists, and loop diureti - Treatment for ataxia in multiple sclerosis
Cochrane Systematic Reviews, 21-Sep-2008
Disabling tremor or ataxia is common in multiple sclerosis (MS) and up to 80% of patients experience tremor or ataxia at some point during their disease. A variety of treatments are available, ranging from pharmacotherapy or stereotactic neurosurgery to n - Treatment for avascular necrosis of bone in people with sickle cell disease
Cochrane Systematic Reviews, 5-Dec-2019
Avascular necrosis of bone is a frequent and severe complication of sickle cell disease and its treatment is not standardised. This is an update of a previously published Cochrane Review. - Treatment for Barrett's oesophagus
Cochrane Systematic Reviews, 4-Mar-2021
- Treatment for bleeding oesophageal varices in people with decompensated liver cirrhosis: a network meta‐analysis
Cochrane Systematic Reviews, 10-Apr-2021
Approximately 40% to 95% of people with liver cirrhosis have oesophageal varices. About 15% to 20% of oesophageal varices bleed within about one to three years after diagnosis. Several different treatments are available, including, among others, endoscopi - Treatment for Charcot-Marie-Tooth disease
Cochrane Systematic Reviews, 28-Apr-2008
Charcot-Marie-Tooth disease (CMT) comprises a large variety of different forms of motor and sensory neuropathies. The most frequent are demyelinating forms (CMT1) and axonal forms (CMT2). The molecular basis of several CMT forms has been clarified during - Treatment for chronic methicillin‐sensitive Staphylococcus aureus pulmonary infection in people with cystic fibrosis
Cochrane Systematic Reviews, 27-Jul-2018
Cystic fibrosis is an inherited life-threatening multisystem disorder with lung disease characterized by abnormally thick airway secretions and persistent bacterial infection. Chronic, progressive lung disease is the most important cause of morbidity and - Treatment for cramps in amyotrophic lateral sclerosis/motor neuron disease
Cochrane Systematic Reviews, 14-Mar-2012
Cramps are painful, involuntary muscle contractions. They commonly affect people with amyotrophic lateral sclerosis/motor neuron disease (ALS/MND) at all stages of the disease. To date, the treatment of muscle cramps in ALS has been largely empirical with - Treatment for cryoglobulinemic and non-cryoglobulinemic peripheral neuropathy associated with hepatitis C virus infection
Cochrane Systematic Reviews, 19-Dec-2014
Peripheral neuropathy is the most common neurologic complication of hepatitis C virus (HCV) infection. The pathophysiology of the neuropathy associated with HCV is not definitively known; however, proposed mechanisms include cryoglobulin deposition in the - Treatment for disseminated intravascular coagulation in patients with acute and chronic leukemia
Cochrane Systematic Reviews, 24-Jun-2015
Disseminated intravascular coagulation (DIC) is an acquired syndrome characterized by systemic intravascular activation of coagulation, leading to deposition of fibrin in the bloodstream. It may occur in patients with acute and chronic leukemia and is par - Treatment for dysphagia (swallowing difficulties) in hereditary ataxia
Cochrane Systematic Reviews, 13-Nov-2015
Hereditary ataxias are a heterogeneous group of disorders resulting in progressive inco-ordination. Swallowing impairment, also known as dysphagia, is a common and potentially life threatening sequel of disease progression. The incidence and nature of dys - Treatment for epilepsy in pregnancy: neurodevelopmental outcomes in the child
Cochrane Systematic Reviews, 30-Oct-2014
Accumulating evidence suggests an association between prenatal exposure to antiepileptic drugs (AEDs) and increased risk of both physical anomalies and neurodevelopmental impairment. Neurodevelopmental impairment is characterised by either a specific defi - Treatment for familial amyotrophic lateral sclerosis/motor neuron disease
Cochrane Systematic Reviews, 21-Jan-2009
Amyotrophic lateral sclerosis (ALS), also known as motor neuron disease (MND), is a rare neurodegenerative disease. Approximately 5% to 7% of ALS/MND patients report a family history of a similarly affected relative. Superoxide dismutase-1 gene mutations - Treatment for femoral pseudoaneurysms
Cochrane Systematic Reviews, 28-Nov-2013
Femoral pseudoaneurysms may complicate up to 8% of vascular interventional procedures. Small pseudoaneurysms can spontaneously clot, but sometimes definitive treatment is needed. Surgery has traditionally been considered the 'gold standard' treatment, alt - Treatment for Fisher syndrome, Bickerstaff's brainstem encephalitis and related disorders
Cochrane Systematic Reviews, 24-Jan-2007
Fisher syndrome is one of the regional variants of Guillain-Barré syndrome, characterised by impairment of eye movements (ophthalmoplegia), incoordination (ataxia) and loss of tendon reflexes (areflexia). It can occur in more limited forms, and may overla
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