- Transurethral radiofrequency collagen denaturation for the treatment of women with urinary incontinence
Cochrane Systematic Reviews, 18-Mar-2015
Transurethral radiofrequency collagen denaturation is a relatively novel, minimally invasive device-based intervention used to treat individuals with urinary incontinence (UI). No systematic review of the evidence supporting its use has been published to - Transvaginal mesh or grafts compared with native tissue repair for vaginal prolapse
Cochrane Systematic Reviews, 8-Nov-2017
A wide variety of grafts have been introduced with the aim of improving the outcomes of traditional native tissue repair (colporrhaphy) for vaginal prolapse. - Transverse verses midline incisions for abdominal surgery
Cochrane Systematic Reviews, 6-Sep-2011
The choice of surgical incision in the abdomen is determined by access. It has been suggested that other parameters such as recovery and complication rate may be influenced by utilising a transverse or oblique rather than a midline incision. However, ther - Trastuzumab-containing regimens for metastatic breast cancer
Cochrane Systematic Reviews, 14-May-2014
Patients with breast cancer are classified as having cells that over-express the human epidermal growth factor receptor 2 (known as HER2-positive) or not (HER2-negative). Typically, patients with HER2-positive disease have a worse prognosis. Trastuzumab i - Trazodone for agitation in dementia
Cochrane Systematic Reviews, 13-May-2008
Behavioural and psychiatric disturbances affect at least 50% of people with Alzheimer's disease and other dementias. Neuroleptic drugs are extensively prescribed to treat behavioural manifestations of dementia in spite of only modest efficacy and a high f - Treadmill training for patients with Parkinson's disease
Cochrane Systematic Reviews, 24-Aug-2015
Treadmill training is used in rehabilitation and is described as improving gait parameters of patients with Parkinson's disease. - Treating BCG-induced disease in children
Cochrane Systematic Reviews, 6-Dec-2012
Bacillus Calmette-Guerín (BCG) is a live attenuated vaccine to prevent tuberculosis, routinely administered at birth as part of the World Health Organization global expanded immunisation programme. Given intradermally, it can cause adverse reactions, incl - Treatment discontinuation with selective serotonin reuptake inhibitors (SSRIs) versus tricyclic antidepressants (TCAs)
Cochrane Systematic Reviews, 31-Oct-2008
Selective serotonin reuptake inhibitors are thought to have better discontinuation rates (i.e. less people dropping out) than tricyclic and heterocyclic antidepressant drugs. It is important to quantify the drop-out rates of different antidepressant drugs - Treatment for amphetamine dependence and abuse
Cochrane Systematic Reviews, 15-Apr-2014
Amphetamine use is of concern because it causes a variety of devastating health physical and neurological consequences, including amphetamine-induced mental disorders. - Treatment for ataxia in multiple sclerosis
Cochrane Systematic Reviews, 21-Sep-2008
Disabling tremor or ataxia is common in multiple sclerosis (MS) and up to 80% of patients experience tremor or ataxia at some point during their disease. A variety of treatments are available, ranging from pharmacotherapy or stereotactic neurosurgery to n - Treatment for Charcot-Marie-Tooth disease
Cochrane Systematic Reviews, 28-Apr-2008
Charcot-Marie-Tooth disease (CMT) comprises a large variety of different forms of motor and sensory neuropathies. The most frequent are demyelinating forms (CMT1) and axonal forms (CMT2). The molecular basis of several CMT forms has been clarified during - Treatment for cramps in amyotrophic lateral sclerosis/motor neuron disease
Cochrane Systematic Reviews, 14-Mar-2012
Cramps are painful, involuntary muscle contractions. They commonly affect people with amyotrophic lateral sclerosis/motor neuron disease (ALS/MND) at all stages of the disease. To date, the treatment of muscle cramps in ALS has been largely empirical with - Treatment for cryoglobulinemic and non-cryoglobulinemic peripheral neuropathy associated with hepatitis C virus infection
Cochrane Systematic Reviews, 19-Dec-2014
Peripheral neuropathy is the most common neurologic complication of hepatitis C virus (HCV) infection. The pathophysiology of the neuropathy associated with HCV is not definitively known; however, proposed mechanisms include cryoglobulin deposition in the - Treatment for dysphagia (swallowing difficulties) in hereditary ataxia
Cochrane Systematic Reviews, 5-Nov-2015
Hereditary ataxias are a heterogeneous group of disorders resulting in progressive inco-ordination. Swallowing impairment, also known as dysphagia, is a common and potentially life threatening sequel of disease progression. The incidence and nature of dys - Treatment for femoral pseudoaneurysms
Cochrane Systematic Reviews, 28-Nov-2013
Femoral pseudoaneurysms may complicate up to 8% of vascular interventional procedures. Small pseudoaneurysms can spontaneously clot, but sometimes definitive treatment is needed. Surgery has traditionally been considered the 'gold standard' treatment, alt - Treatment for Fisher syndrome, Bickerstaff's brainstem encephalitis and related disorders
Cochrane Systematic Reviews, 10-Nov-2009
Fisher syndrome is one of the regional variants of Guillain-Barré syndrome, characterised by impairment of eye movements (ophthalmoplegia), incoordination (ataxia) and loss of tendon reflexes (areflexia). It can occur in more limited forms, and may overla - Treatment for hepatitis C virus-associated mixed cryoglobulinaemia
Cochrane Systematic Reviews, 26-Apr-2018
Hepatitis C virus (HCV)-associated mixed cryoglobulinaemia is the manifestation of an inflammation of small and medium-sized vessels produced by a pathogenic IgM with rheumatoid factor activity generated by an expansion of B-cells. The immune complexes fo - Treatment for inclusion body myositis
Cochrane Systematic Reviews, 8-Jul-2015
Inclusion body myositis (IBM) is a late-onset inflammatory muscle disease (myopathy) associated with progressive proximal and distal limb muscle atrophy and weakness. Treatment options have attempted to target inflammatory and atrophic features of this co - Treatment for inhalant dependence and abuse
Cochrane Systematic Reviews, 25-Oct-2010
Inhalants are being abused by large numbers of people throughout the world, particularly socio-economically disadvantaged children and adolescents. The neuropsychological effects of acute and chronic inhalant abuse include motor impairment, alterations in - Treatment for leiomyosarcoma and leiomyoma in children with HIV infection
Cochrane Systematic Reviews, 14-Apr-2010
Smooth muscle tumour (SMT) composed of leiomyoma and leiomyosarcoma recently has been described in many HIV-infected children. Leiomyosarcoma has become the second most frequent malignancy in children with HIV infection or other immunodeficiency diseases
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