- Treatment for speech disorder in Friedreich ataxia and other hereditary ataxia syndromes
Cochrane Systematic Reviews, 23-Oct-2014
Hereditary ataxia syndromes can result in significant speech impairment, a symptom thought to be responsive to treatment. The type of speech impairment most commonly reported in hereditary ataxias is dysarthria. Dysarthria is a collective term referring t - Treatment for superficial infusion thrombophlebitis of the upper extremity
Cochrane Systematic Reviews, 16-Nov-2015
Although superficial thrombophlebitis of the upper extremity represents a frequent complication of intravenous catheters inserted into the peripheral veins of the forearm or hand, no consensus exists on the optimal management of this condition in clinical - Treatment for superficial thrombophlebitis of the leg
Cochrane Systematic Reviews, 20-Feb-2018
The optimal treatment of superficial thrombophlebitis (ST) of the legs remains poorly defined. While improving or relieving the local painful symptoms, treatment should aim at preventing venous thromboembolism (VTE), which might complicate the natural his - Treatment for thoracic outlet syndrome
Cochrane Systematic Reviews, 21-Nov-2014
Thoracic outlet syndrome (TOS) is one of the most controversial diagnoses in clinical medicine. Despite many reports of operative and non-operative interventions, rigorous scientific investigation of this syndrome leading to evidence-based management is l - Treatment for ulnar neuropathy at the elbow
Cochrane Systematic Reviews, 17-Oct-2016
Ulnar neuropathy at the elbow (UNE) is the second most common entrapment neuropathy after carpal tunnel syndrome. Treatment may be conservative or surgical, but optimal management remains controversial. This is an update of a review first published in 201 - Treatment for women with postpartum iron deficiency anaemia
Cochrane Systematic Reviews, 9-Sep-2015
Postpartum anaemia is associated with breathlessness, tiredness, palpitations and maternal infections. Blood transfusions or iron supplementation have been used in the treatment of iron deficiency anaemia. Recently other anaemia treatments, in particular - Treatment for women with postpartum iron deficiency anaemia
Cochrane Systematic Reviews, 12-Aug-2015
Postpartum iron deficiency anaemia is caused by bleeding or inadequate dietary iron intake/uptake. This condition is defined by iron deficiency accompanied by a lower than normal blood haemoglobin concentration, although this can be affected by factors ot - Treatment Foster Care for improving outcomes in children and young people
Cochrane Systematic Reviews, 1-May-2008
Treatment foster care (TFC) is a foster family-based intervention that aims to provide young people (and, where appropriate, their families) with a tailored programme designed to effect positive changes in their lives. TFC was designed specifically to cat - Treatment including anthracyclines versus treatment not including anthracyclines for childhood cancer
Cochrane Systematic Reviews, 4-Sep-2014
One of the most important adverse effects of anthracyclines is cardiotoxicity. A well-informed decision on the use of anthracyclines in the treatment of childhood cancers should be based on evidence regarding both antitumour efficacy and cardiotoxicity. T - Treatment of dental and orthodontic complications in thalassaemia
Cochrane Systematic Reviews, 1-Aug-2019
Thalassaemia is a quantitative abnormality of haemoglobin caused by mutations in genes controlling production of alpha or beta globins. Abnormally unpaired globin chains cause haemolytic anaemia by causing membrane damage and cell death within organ syste - Treatment of dental complications in sickle cell disease
Cochrane Systematic Reviews, 25-Nov-2019
Sickle cell disease is the most common single gene disorder and the commonest haemoglobinopathy found with high prevalence in many populations across the world. Management of dental complications in people with sickle cell disease requires special conside - Treatment of distal deep vein thrombosis
Cochrane Systematic Reviews, 9-Apr-2020
The treatment of distal (below the knee) deep vein thrombosis (DVT) is not clearly established. Distal DVT can either be treated with anticoagulation, or monitored with close follow-up to detect progression to the proximal veins (above the knee), which re - Treatment of epilepsy for people with Alzheimer's disease
Cochrane Systematic Reviews,
Any type of seizure can be observed in Alzheimer's disease. Antiepileptic drugs seem to prevent the recurrence of epileptic seizures in most people with Alzheimer's disease. There are pharmacological and non-pharmacological treatments for epilepsy in peop - Treatment of fatigue in amyotrophic lateral sclerosis/motor neuron disease
Cochrane Systematic Reviews, 2-Jan-2018
Amyotrophic lateral sclerosis (ALS), also known as motor neuron disease (MND), is terminal, progressive neurological condition for which there are no curative treatments. Among people with ALS/MND, fatigue is a common and debilitating symptom, which is ch - Treatment of hypertension in peripheral arterial disease
Cochrane Systematic Reviews, 4-Dec-2013
Peripheral arterial disease (PAD) causes considerable morbidity and mortality. Hypertension is a risk factor for PAD. Treatment for hypertension must be compatible with the symptoms of PAD. Controversy regarding the effects of beta-adrenoreceptor blockade - Treatment of infantile spasms
Cochrane Systematic Reviews, 23-May-2013
Infantile spasms (West's Syndrome) is a syndrome that includes a peculiar type of epileptic seizure—the spasms—and an electroencephalographic (EEG) abnormality often called hypsarrhythmia. Psychomotor retardation is frequently found at follow-up. Approxim - Treatment of Kaposi sarcoma in children with HIV-1 infection
Cochrane Systematic Reviews, 26-Jan-2014
Kaposi sarcoma (KS) remains the second most frequently diagnosed HIV-related malignancy (HRM) worldwide and most common HRM in sub-Saharan Africa where HIV is most prevalent and human herpesvirus 8 (HHV-8), the precipitating agent for the development of K - Treatment of latent tuberculosis infection in HIV infected persons
Cochrane Systematic Reviews, 10-Nov-2009
Individuals with human immunodeficiency virus (HIV) infection are at an increased risk of developing active tuberculosis (TB). It is known that treatment of latent TB infection (LTBI), also referred to as TB preventive therapy or chemoprophylaxis, helps t - Treatment of Lennox‐Gastaut syndrome
Cochrane Systematic Reviews, 29-Jan-2013
The Lennox-Gastaut syndrome (LGS) is an age-specific disorder, characterised by epileptic seizures, a characteristic electroencephalogram (EEG), psychomotor delay and behavioural disorder. It occurs more frequently in males and onset is usually before the - Treatment of newly diagnosed glioblastoma in the elderly: a network meta‐analysis
Cochrane Systematic Reviews, 27-Mar-2020
A glioblastoma is a fatal type of brain tumour for which the standard of care is maximum surgical resection followed by chemoradiotherapy, when possible. Age is an important consideration in this disease, as older age is associated with shorter survival a
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