- Thrombophilia testing for prevention of recurrent venous thromboembolism
Cochrane Systematic Reviews, 12-Dec-2012
Tests for thrombophilia are being performed on a large scale in people after venous thromboembolism (VTE) even though the benefits of testing are still subject to debate. The most important benefit would be a reduction in the risk of recurrent VTE due to - Thrombopoietin mimetics for patients with myelodysplastic syndromes
Cochrane Systematic Reviews, 30-Sep-2017
Myelodysplastic syndrome (MDS) is one of the most frequent haematologic malignancies of the elderly population and characterised by progenitor cell dysplasia with ineffective haematopoiesis and a high rate of transformation to acute myeloid leukaemia (AML - Thrombopoietin receptor agonists for prevention and treatment of chemotherapy‐induced thrombocytopenia in patients with solid tumours
Cochrane Systematic Reviews, 27-Nov-2017
Chemotherapy-induced thrombocytopenia (CIT) is defined as a peripheral platelet count less than 100×109/L, with or without bleeding in cancer patients receiving myelosuppressive chemotherapy. CIT is a significant medical problem during chemotherapy, and i - Thromboprophylaxis for trauma patients
Cochrane Systematic Reviews, 27-Feb-2013
Trauma is a leading causes of death and disability in young people. Venous thromboembolism (VTE) is a principal cause of death. Trauma patients are at high risk of deep vein thrombosis (DVT). The incidence varies according to the method used to measure th - Through‐knee versus above‐knee amputation for vascular and non‐vascular major lower limb amputations
Cochrane Systematic Reviews, 14-Dec-2021
Diabetes and vascular disease are the leading causes of lower limb amputation. Currently, 463 million adults are living with diabetes, and 202 million with peripheral vascular disease, worldwide. When a lower limb amputation is considered, preservation of - Thymectomy for non-thymomatous myasthenia gravis
Cochrane Systematic Reviews, 11-Oct-2013
Treatments currently used for patients with myasthenia gravis (MG) include steroids, non-steroid immune suppressive agents, plasma exchange, intravenous immunoglobulin and thymectomy. Data from randomized controlled trials (RCTs) support the use of some o - Thymic peptides for treatment of cancer patients
Cochrane Systematic Reviews, 16-Feb-2011
Purified thymus extracts (pTE) and synthetic thymic peptides (sTP) are thought to enhance the immune system of cancer patients in order to fight the growth of tumour cells and to resist infections due to immunosuppression induced by the disease and antine - Thyroid hormone replacement for subclinical hypothyroidism
Cochrane Systematic Reviews, 18-Jul-2007
Subclinical hypothyroidism is defined as an elevated serum thyroid-stimulating hormone (TSH) level with normal free thyroid hormones values. The prevalence of subclinical hypothyroidism is 4% to 8% in the general population, and up to 15% to 18% in women - Thyroid hormone supplementation for the prevention of morbidity and mortality in infants undergoing cardiac surgery
Cochrane Systematic Reviews, 13-Feb-2008
Paediatric studies have demonstrated that cardiopulmonary bypass is associated with a decline in thyroid hormone levels. Adult patients who undergo open heart surgery and receive triiodothyronine supplementation have demonstrated a dose-dependent increase - Thyroid hormones for acute kidney injury
Cochrane Systematic Reviews, 25-Nov-2012
Acute kidney injury (AKI), which is common in hospitalised patients, is associated with significant morbidity and mortality. Despite recent advances in treatment, AKI outcomes have not changed substantially during the past four decades, and incidence is i - Thyroid hormones for preventing neurodevelopmental impairment in preterm infants
Cochrane Systematic Reviews, 23-Oct-2001
Observational studies have shown an association between transiently low thyroid hormone levels in preterm infants in the first weeks of life (transient hypothyroxinemia) and abnormal neurodevelopmental outcome. Thyroid hormone therapy might prevent this m - Thyroid surgery for Graves’ disease and Graves’ ophthalmopathy
Cochrane Systematic Reviews, 12-Nov-2015
Graves' disease is an autoimmune disease caused by the production of auto-antibodies against the thyroid-stimulating hormone receptor, which stimulates follicular cell production of thyroid hormone. It is the commonest cause of hyperthyroidism and may cau - Thyrotropin‐releasing hormone added to corticosteroids for women at risk of preterm birth for preventing neonatal respiratory disease
Cochrane Systematic Reviews, 21-Nov-2013
Thyrotropin-releasing hormones (TRH) added to prenatal corticosteroids has been suggested as a way to further reduce breathing problems and neonatal lung disease in infants born preterm. - Thyroxine replacement for subfertile women with euthyroid autoimmune thyroid disease or subclinical hypothyroidism
Cochrane Systematic Reviews, 25-Jun-2019
Thyroid disease is the second most common endocrine disorder affecting women of reproductive age. Subclinical hypothyroidism is diagnosed by an elevated thyroid-stimulating hormone concentration with a normal concentration of free thyroxine hormone. Autoi - Tiagabine add‐on therapy for drug‐resistant focal epilepsy
Cochrane Systematic Reviews, 14-Oct-2019
Epilepsy is a common neurological condition that affects up to 1% of the population. Nearly 30% of people with epilepsy are resistant to currently available antiepileptic drugs (AEDs) and require treatment with multiple antiepileptic drugs in combination. - Tiagabine for acute affective episodes in bipolar disorder
Cochrane Systematic Reviews, 12-Dec-2012
Bipolar disorder is a common recurrent illness with high levels of chronicity. Treatment resistance persists despite the use of established medications, such as lithium and valproate. New medications are required for the treatment of refractory cases. Som - Tiagabine in the maintenance treatment of bipolar disorder
Cochrane Systematic Reviews, 15-May-2012
Tiagabine, an anticonvulsant, has been reported to have efficacy in prophylactic treatment of bipolar disorder in case reports and in case series. - Tianma Gouteng Yin Formula for treating primary hypertension
Cochrane Systematic Reviews, 14-May-2012
Tianma Gouteng Yin Formula (TGYF) is widely used to treat hypertension-related symptoms in clinical practice in East Asia. It has been shown to have a blood pressure lowering effect, reducing total cholesterol, improving clinical symptoms and quality of l - Ticlopidine versus oral anticoagulation for coronary stenting
Cochrane Systematic Reviews, 23-Oct-2001
A two to four week course of ticlopidine plus aspirin following coronary stenting is considered effective in preventing thrombotic occlusion of the stented vessel and safe in regards to bleeding and peripheral vascular complications. However, rare, althou - Tidal versus other forms of peritoneal dialysis for acute kidney injury
Cochrane Systematic Reviews, 17-Apr-2012
Acute kidney injury (AKI) is associated with substantial morbidity and mortality. Recent studies have shown that dialysis dose was a major factor associated with patient survival. Unresolved questions persist about which mode of peritoneal dialysis (PD) s
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