- Tamoxifen for early breast cancer
Cochrane Systematic Reviews, 5-Aug-2008
There have been many randomised trials of adjuvant tamoxifen among women with early breast cancer, and an updated overview of their results is presented. - Tamoxifen or letrozole versus standard methods for women with estrogen-receptor positive breast cancer undergoing oocyte or embryo cryopreservation in assisted reproduction
Cochrane Systematic Reviews, 22-Jan-2014
Cryopreservation of oocytes or embryos preceded by controlled ovarian stimulation (COS) can increase the chance of future pregnancy in women with breast cancer who risk therapy-induced ovarian failure. In women with estrogen-receptor (ER) positive breast - Target-controlled infusion versus manually-controlled infusion of propofol for general anaesthesia or sedation in adults
Cochrane Systematic Reviews, 1-Jul-2016
Continuous infusions of the intravenous anaesthetic propofol are commonly used to induce and maintain sedation and general anaesthesia. Infusion devices can be manually controlled (MCI) where the anaesthetist makes each change to the infusion rate or targ - Targeted therapy for advanced renal cell carcinoma
Cochrane Systematic Reviews, 7-Nov-2011
Advanced renal cell carcinoma has been resistant to drug therapy of different types and new types of drug therapy are needed. Targeted agents inhibit known molecular pathways and have been tested in renal cancer for just over a decade. - Targeting intensive glycaemic control versus targeting conventional glycaemic control for type 2 diabetes mellitus
Cochrane Systematic Reviews, 28-Jul-2015
Patients with type 2 diabetes mellitus (T2D) have an increased risk of cardiovascular disease and mortality compared to the background population. Observational studies report an association between reduced blood glucose and reduced risk of both micro- an - Task shifting from doctors to non-doctors for initiation and maintenance of antiretroviral therapy
Cochrane Systematic Reviews, 1-Jul-2014
The high levels of healthcare worker shortage is recognised as a severe impediment to increasing patients' access to antiretroviral therapy. This is particularly of concern where the burden of disease is greatest and the access to trained doctors is limit - Task-oriented interventions for children with developmental co-ordination disorder
Cochrane Systematic Reviews, 1-Aug-2017
Developmental co-ordination disorder (DCD) is a common childhood disorder, which can persist into adolescence and adulthood. Children with DCD have difficulties in performing the essential motor tasks required for self-care, academic, social and recreatio - Taxane-based chemohormonal therapy for metastatic hormone-sensitive prostate cancer
Cochrane Systematic Reviews, 13-Oct-2018
There has been considerable development in the treatment of advanced prostate cancer over the last decade. A number of agents, including docetaxel, cabazitaxel, abiraterone acetate, enzalutamide and sipuleucel-T, have been reported to improve outcomes in - Technique modifications for reducing the risks from amniocentesis or chorionic villus sampling
Cochrane Systematic Reviews, 10-Jul-2012
Currently, the techniques for amniocentesis and chorionic villus sampling (CVS) tend to be described in local and national guidelines, but certain aspects, including the choice of instruments, is predominantly based upon the operator's personal preference - Techniques and materials for closure of the abdominal wall in caesarean section
Cochrane Systematic Reviews, 12-Aug-2008
There is a variety of techniques for closing the abdominal wall during caesarean section. Some methods may be better in terms of postoperative recovery and other important outcomes. - Techniques for assisting difficult delivery at caesarean section
Cochrane Systematic Reviews, 28-Jan-2016
Caesarean section involves making an incision in the woman's abdomen and cutting through the uterine muscle. The baby is then delivered through that incision. Difficult caesarean birth may result in injury for the infant or complications for the mother. M - Techniques for caesarean section
Cochrane Systematic Reviews, 8-Aug-2012
Rates of caesarean section (CS) have been rising globally. It is important to use the most effective and safe technique. - Techniques for pelvic surgery in subfertility
Cochrane Systematic Reviews, 20-Sep-2010
Since the introduction of in-vitro fertilisation (IVF) tubal surgery has been less frequently undertaken as a technique to improve fertility in women with damaged fallopian tubes. There are various surgical techniques that can be used to repair blocked or - Techniques of flushing and reperfusion for liver transplantation
Cochrane Systematic Reviews, 14-Feb-2012
Various techniques of flushing and reperfusion have been advocated to improve outcomes after liver transplantation. There is considerable uncertainty as to which method is superior. - Techniques to ascertain correct endotracheal tube placement in neonates
Cochrane Systematic Reviews, 5-Jul-2018
The success rate of correct endotracheal tube (ETT) placement for junior medical staff is less than 50% and accidental oesophageal intubation is common. Rapid confirmation of correct tube placement is important because tube malposition is associated with - Technological aids for the rehabilitation of memory and executive functioning in children and adolescents with acquired brain injury
Cochrane Systematic Reviews, 1-Jul-2016
The use of technology in healthcare settings is on the increase and may represent a cost-effective means of delivering rehabilitation. Reductions in treatment time, and delivery in the home, are also thought to be benefits of this approach. Children and a - Tegaserod for the treatment of irritable bowel syndrome and chronic constipation
Cochrane Systematic Reviews, 11-Jun-2008
IBS is a complex disorder that encompasses a wide profile of symptoms. The symptoms of chronic constipation frequently resemble those of constipation-predominant IBS. Current drug treatments for irritable bowel syndrome (IBS) are of limited value. Many ta - Teicoplanin versus vancomycin for proven or suspected infection
Cochrane Systematic Reviews, 10-May-2010
Vancomycin and teicoplanin are commonly used to treat gram-positive infections, particularly those caused by methicillin-resistant Staphylococcus aureus (MRSA). There is uncertainty regarding the effects of teicoplanin compared to vancomycin on kidney fun - Telehealthcare for asthma
Cochrane Systematic Reviews, 19-Jun-2012
Healthcare systems internationally need to consider new models of care to cater for the increasing numbers of people with asthma. Telehealthcare interventions are increasingly being seen by policymakers as a potential means of delivering asthma care. We d - Telehealthcare for chronic obstructive pulmonary disease
Cochrane Systematic Reviews, 19-Jun-2012
Chronic obstructive pulmonary disease (COPD) is a disease of irreversible airways obstruction in which patients often suffer exacerbations. Sometimes these exacerbations need hospital care: telehealthcare has the potential to reduce admission to hospital
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