- Thiamine for Alzheimer's disease
Cochrane Systematic Reviews, 5-May-2008
Vitamin B1 (thiamine) deficiency plays an important role in Wernicke-Korsakoff syndrome. This is a form of brain damage occurring in long-term alcoholics who rely mainly on alcohol for nutrition. The acute syndrome (Wernicke's encephalopathy) is normally - Thiamine for prevention and treatment of Wernicke‐Korsakoff Syndrome in people who abuse alcohol
Cochrane Systematic Reviews, 1-Jul-2013
Autopsy studies suggest that Wernicke-Korsakoff syndrome (WKS) is not a rare disorder, particularly in individuals who abuse alcohol. Thiamine has been established as the treatment of choice for over 50 years, but uncertainty remains about appropriate dos - Thiazide diuretics and the risk of hip fracture
Cochrane Systematic Reviews, 5-Sep-2011
Thiazide diuretics are one of the most commonly prescribed antihypertensive agents worldwide. Thiazides reduce urinary calcium excretion. Chronic ingestion of thiazides is associated with higher bone mineral density. It has been suggested that thiazides m - Thienopyridine derivatives versus aspirin for preventing stroke and other serious vascular events in high vascular risk patients
Cochrane Systematic Reviews, 7-Oct-2009
Aspirin is the most widely studied and prescribed antiplatelet agent for preventing serious vascular events, reducing the odds of such events among high vascular risk patients by about a quarter. Thienopyridine derivatives inhibit platelet activation by a - Thioridazine for dementia
Cochrane Systematic Reviews, 23-Oct-2001
Neuroleptic drugs are controversial treatments in dementia, with evidence accumulating that they may hasten clinical decline. Despite these concerns, they are commonly prescribed for elderly and demented patients. Thioridazine, a phenothiazine neuroleptic - Thioridazine for schizophrenia
Cochrane Systematic Reviews, 12-Apr-2011
Thioridazine is an antipsychotic that can still be used for schizophrenia although it is associated with the cardiac arrhythmia, torsades de pointe. - Third generation cephalosporins versus conventional antibiotics for treating acute bacterial meningitis
Cochrane Systematic Reviews, 26-May-2013
Antibiotic therapy for suspected acute bacterial meningitis (ABM) needs to be started immediately, even before the results of cerebrospinal fluid (CSF) culture and antibiotic sensitivity are available. Immediate commencement of effective treatment using t - Third trimester antiviral prophylaxis for preventing maternal genital herpes simplex virus (HSV) recurrences and neonatal infection
Cochrane Systematic Reviews, 4-Feb-2008
Genital herpes simplex virus (HSV) infection is one of the most common viral sexually transmitted infections. The majority of women with genital herpes will have a recurrence during pregnancy. Transmission of the virus from mother to fetus typically occur - 'Third wave' cognitive and behavioural therapies versus other psychological therapies for depression
Cochrane Systematic Reviews, 17-Oct-2013
So-called 'third wave' cognitive and behavioural therapies represents a new generation of psychological therapies that are increasingly being used in the treatment of psychological problems. However, the effectiveness and acceptability of third wave cogni - 'Third wave' cognitive and behavioural therapies versus treatment as usual for depression
Cochrane Systematic Reviews, 18-Oct-2013
So-called 'third wave' cognitive and behavioural therapies represent a new generation of psychological therapies that are increasingly being used in the treatment of psychological problems. However, the effectiveness and acceptability of third-wave cognit - Thoracic endovascular repair (TEVAR) versus open surgery for blunt traumatic thoracic aortic injury
Cochrane Systematic Reviews, 6-Feb-2019
Blunt traumatic thoracic aortic injury (BTAI) is a life-threatening surgical emergency associated with mortality up to 8000 per year, most commonly caused by rapid acceleration/deceleration injury sustained through motor vehicle accident and/or blunt thor - Thoracic imaging tests for the diagnosis of COVID‐19
Cochrane Systematic Reviews, 16-Mar-2021
The respiratory illness caused by SARS-CoV-2 infection continues to present diagnostic challenges. Our 2020 edition of this review showed thoracic (chest) imaging to be sensitive and moderately specific in the diagnosis of coronavirus disease 2019 (COVID- - Thoracic stent graft versus surgery for thoracic aneurysm
Cochrane Systematic Reviews, 6-Jun-2016
Thoracic aortic aneurysm (TAA) is an uncommon disease with an incidence of 10.4 per 100,000 inhabitants. It occurs mainly in older individuals and is evenly distributed among both sexes. There are no signs or symptoms indicative of the presence of the dis - Three dimensional versus two dimensional imaging for laparoscopic cholecystectomy
Cochrane Systematic Reviews, 6-Dec-2010
The benefits and harms of three dimensional imaging versus traditional two dimensional imaging for laparoscopic cholecystectomy are not known. - Three‐ or four‐ versus two‐drug antiretroviral maintenance regimens for HIV infection
Cochrane Systematic Reviews, 20-Oct-2003
Combination antiretroviral therapy administered to HIV-infected individuals has been shown to decrease viral replication, improve immunologic function and delay the progression of HIV infection. However, because patient adherence to complicated combinatio - Three‐dimensional saline infusion sonography compared to two‐dimensional saline infusion sonography for the diagnosis of focal intracavitary lesions
Cochrane Systematic Reviews, 5-May-2017
Focal abnormalities most commonly acquired within the uterine cavity include endometrial polyps (arising from the endometrium) and submucous fibroids (arising from the myometrium). These benign abnormalities can cause several problems, including abnormal - Thromboelastography (TEG) and rotational thromboelastometry (ROTEM) for trauma‑induced coagulopathy in adult trauma patients with bleeding
Cochrane Systematic Reviews, 16-Feb-2015
Trauma-induced coagulopathy (TIC) is a disorder of the blood clotting process that occurs soon after trauma injury. A diagnosis of TIC on admission is associated with increased mortality rates, increased burdens of transfusion, greater risks of complicati - Thromboelastography (TEG) or thromboelastometry (ROTEM) to monitor haemostatic treatment versus usual care in adults or children with bleeding
Cochrane Systematic Reviews, 22-Aug-2016
Severe bleeding and coagulopathy are serious clinical conditions that are associated with high mortality. Thromboelastography (TEG) and thromboelastometry (ROTEM) are increasingly used to guide transfusion strategy but their roles remain disputed. This re - Thrombolysis (different doses, routes of administration and agents) for acute ischaemic stroke
Cochrane Systematic Reviews, 31-May-2013
Stroke is a leading cause of death and disability world wide. Thrombolysis with recombinant tissue plasminogen activator (rt-PA) is licensed for treatment of acute ischaemic stroke in the early hours after symptom onset. It has been shown in randomised co - Thrombolysis for acute ischaemic stroke
Cochrane Systematic Reviews, 29-Jul-2014
Most strokes are due to blockage of an artery in the brain by a blood clot. Prompt treatment with thrombolytic drugs can restore blood flow before major brain damage has occurred and improve recovery after stroke in some people. Thrombolytic drugs, howeve
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