- Vaccines for preventing malaria (blood-stage)
Cochrane Systematic Reviews, 10-Nov-2008
A malaria vaccine is needed because of the heavy burden of mortality and morbidity due to this disease. This review describes the results of trials of blood (asexual)-stage vaccines. Several are under development, but only one (MSP/RESA, also known as Com - Vaccines for preventing malaria (pre-erythrocytic)
Cochrane Systematic Reviews, 10-Nov-2008
Vaccines against all stages of the malaria parasite are in development, mainly for Plasmodium falciparum, which causes the most serious form of malaria. Pre-erythrocytic vaccines act to prevent or delay a malaria attack by attacking the sporozoite and liv - Vaccines for preventing malaria (SPf66)
Cochrane Systematic Reviews, 18-Feb-2009
A malaria vaccine is badly needed. SPf66 was one of the earliest vaccines developed. It is a synthetic peptide vaccine containing antigens from the blood stages of malaria linked together with an antigen from the sporozoite stage, and is targeted mainly a - Vaccines for preventing plague
Cochrane Systematic Reviews, 10-Jan-2012
Plague is endemic in China, Mongolia, Burma, Vietnam, Indonesia, India, large parts of Southern Africa, the United States and South America. There are three types of vaccines (live attenuated, killed and F1 fraction) with varying means of administration. - Vaccines for preventing pneumococcal infection in adults
Cochrane Systematic Reviews, 19-Nov-2012
Diseases caused by Streptococcus pneumoniae (S. pneumoniae) continue to cause substantial morbidity and mortality globally. Whilst pneumococcal polysaccharide vaccines (PPVs) have the potential to prevent disease and death, the degree of protection afford - Vaccines for preventing smallpox
Cochrane Systematic Reviews, 10-Nov-2008
Smallpox was eradicated by 1980, but its possible use as a bioweapon has rekindled interest in the development of protective vaccines. Therefore, stockpiled calf lymph-derived vaccines and recently developed cell-cultured vaccines have been investigated t - Vaccines for preventing tick-borne encephalitis
Cochrane Systematic Reviews, 12-Nov-2008
Tick-borne encephalitis (TBE) is a disease of the central nervous system caused by a tick-borne viral infection. TBE can lead to severe neurological syndromes such as meningitis, meningoencephalitis, and meningoencephalomyelitis, which can result in death - Vaccines for preventing typhoid fever
Cochrane Systematic Reviews, 30-May-2018
Typhoid fever and paratyphoid fever continue to be important causes of illness and death, particularly among children and adolescents in south-central and southeast Asia. Two typhoid vaccines are widely available, Ty21a (oral) and Vi polysaccharide (paren - Vaccines for prophylaxis of viral infections in patients with hematological malignancies
Cochrane Systematic Reviews, 26-Jan-2011
Viral infections cause significant morbidity and mortality in patients with hematological malignancies. It remains uncertain whether viral vaccinations in these patients are supported by good evidence. - Vaccines for the common cold
Cochrane Systematic Reviews, 17-May-2017
The common cold is a spontaneously remitting infection of the upper respiratory tract, characterised by a runny nose, nasal congestion, sneezing, cough, malaise, sore throat, and fever (usually < 37.8º C). The widespread morbidity caused by the common col - Vaccines for women for preventing neonatal tetanus
Cochrane Systematic Reviews, 23-Jun-2015
Tetanus is an acute, often fatal, disease caused by an exotoxin produced by Clostridium tetani. It occurs in newborn infants born to mothers who do not have sufficient circulating antibodies to protect the infant passively, by transplacental transfer. Pre - Vaginal chlorhexidine during labour for preventing maternal and neonatal infections (excluding Group B Streptococcal and HIV)
Cochrane Systematic Reviews, 12-Sep-2014
The incidence of chorioamnionitis occurs in between eight and 12 women for every 1000 live births and 96% of cases of chorioamnionitis are due to ascending infection. Following spontaneous vaginal delivery, 1% to 4% of women develop postpartum endometriti - Vaginal chlorhexidine during labour to prevent early-onset neonatal group B streptococcal infection
Cochrane Systematic Reviews, 4-Dec-2014
Although early-onset group B ß-hemolytic streptococcus (GBS) infection is rare, it accounts for approximately 30% of neonatal infections, has a high mortality rate, and is acquired through vertical transmission from colonized mothers. Several trials have - Vaginal dilator therapy for women receiving pelvic radiotherapy
Cochrane Systematic Reviews, 17-Jul-2018
Vaginal dilation therapy is advocated after pelvic radiotherapy to prevent stenosis (abnormal narrowing of the vagina), but can be uncomfortable and psychologically distressing. - Vaginal disinfection for preventing mother-to-child transmission of HIV infection
Cochrane Systematic Reviews, 5-Sep-2011
Mother-to-child transmission (MTCT) of HIV infection is one of the most tragic consequences of the HIV epidemic, especially in resource-limited countries, resulting in about 650 000 new paediatric HIV infections each year worldwide. The paediatric HIV epi - Vaginal misoprostol for cervical ripening and induction of labour
Cochrane Systematic Reviews, 20-Nov-2012
Misoprostol (Cytotec, Searle) is a prostaglandin E1 analogue widely used for off-label indications such as induction of abortion and of labour. This is one of a series of reviews of methods of cervical ripening and labour induction using standardised meth - Vaginal preparation with antiseptic solution before cesarean section for preventing postoperative infections
Cochrane Systematic Reviews, 11-Jul-2018
Cesarean delivery is one of the most common surgical procedures performed by obstetricians. Infectious morbidity after cesarean delivery can have a tremendous impact on the postpartum woman's return to normal function and her ability to care for her baby. - Vaginal prostaglandin (PGE2 and PGF2a) for induction of labour at term
Cochrane Systematic Reviews, 18-Jun-2014
Prostaglandins have been used for induction of labour since the 1960s. This is one of a series of reviews evaluating methods of induction of labour. This review focuses on prostaglandins given per vaginam, evaluating these in comparison with placebo (or e - Vagus nerve stimulation for partial seizures
Cochrane Systematic Reviews, 1-Apr-2015
Vagus nerve stimulation (VNS) is a neuromodulatory treatment that is used as an adjunctive therapy for treating people with medically refractory epilepsy. VNS consists of chronic intermittent electrical stimulation of the vagus nerve, delivered by a progr - Valacyclovir versus acyclovir for the treatment of herpes zoster ophthalmicus in immunocompetent patients
Cochrane Systematic Reviews, 8-Nov-2016
Herpes zoster ophthalmicus affects the eye and vision, and is caused by the reactivation of the varicella zoster virus in the distribution of the first division of the trigeminal nerve. An aggressive management of acute herpes zoster ophthalmicus with sys
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