- Stem cell treatment for acute myocardial infarction
Cochrane Systematic Reviews, 21-Sep-2015
Cell transplantation offers a potential therapeutic approach to the repair and regeneration of damaged vascular and cardiac tissue after acute myocardial infarction (AMI). This has resulted in multiple randomised controlled trials (RCTs) across the world. - Stent placement versus surgery for coarctation of the thoracic aorta
Cochrane Systematic Reviews, 3-Apr-2012
Coarctation of the aorta (CoA) accounts for 5% to 7% of congenital heart disease, with an incidence of 0.3 to 0.4 per 1000 live births. Surgery was the only choice of therapy for CoA until 1982 when balloon angioplasty became an available alternative for - Stent placement versus surgical palliation for adults with malignant gastric outlet obstruction
Cochrane Systematic Reviews, 29-May-2018
Malignant gastric outlet obstruction is the clinical and pathological consequence of cancerous disease causing a mechanical obstruction to gastric emptying. It usually occurs when malignancy is at an advanced stage; therefore, people have a limited life e - Stepping down the dose of inhaled corticosteroids for adults with asthma
Cochrane Systematic Reviews, 1-Feb-2017
Asthma is a condition of the airways affecting more than 300 million adults and children worldwide. National and international guidelines recommend titrating up the dose of inhaled corticosteroids (ICS) to gain symptom control at the lowest possible dose - Stereotactic radiotherapy for vestibular schwannoma
Cochrane Systematic Reviews, 15-Dec-2014
Vestibular schwannomas (acoustic neuromas) are common benign tumours that arise from the Schwann cells of the vestibular nerve. Management options include observation with neuroradiological follow-up, microsurgical resection and stereotactic radiotherapy. - Steroid avoidance or withdrawal for kidney transplant recipients
Cochrane Systematic Reviews, 2-Aug-2016
Steroid-sparing strategies have been attempted in recent decades to avoid morbidity from long-term steroid intake among kidney transplant recipients. Previous systematic reviews of steroid withdrawal after kidney transplantation have shown a significant i - Steroid avoidance or withdrawal for pancreas and pancreas with kidney transplant recipients
Cochrane Systematic Reviews, 12-Sep-2014
Pancreas or kidney-pancreas transplantation improves survival and quality of life for people with type 1 diabetes mellitus and kidney failure. Immunosuppression after transplantation is associated with complications. Steroids have adverse effects on cardi - Steroid hormones for contraception in women with sickle cell disease
Cochrane Systematic Reviews, 14-Nov-2011
Whether steroid contraceptives are appropriate for women with homozygous sickle cell (SS) disease remains unresolved. Historically, women with sickle cell disease have experienced difficult pregnancies, characterized by high rates of maternal mortality an - Steroidal contraceptives and bone fractures in women: evidence from observational studies
Cochrane Systematic Reviews, 14-Jul-2015
Age-related decline in bone mass increases the risk of skeletal fractures, especially those of the hip, spine, and wrist. Steroidal contraceptives have been associated with changes in bone mineral density in women. Whether such changes affect the risk of - Steroidal contraceptives: effect on bone fractures in women
Cochrane Systematic Reviews, 16-Jun-2014
Steroidal contraceptive use has been associated with changes in bone mineral density in women. Whether such changes increase the risk of fractures later in life is not clear. Osteoporosis is a major public health concern. Age-related decline in bone mass - Steroid-eluting sinus stents for improving symptoms in chronic rhinosinusitis patients undergoing functional endoscopic sinus surgery
Cochrane Systematic Reviews, 8-Jun-2015
Functional endoscopic sinus surgery (FESS) has become a well-established approach for treating patients with chronic rhinosinusitis (CRS) refractory to medical management. However, the surgical outcome may be compromised by postoperative inflammation, pol - Steroids for improving recovery following tonsillectomy in children
Cochrane Systematic Reviews, 10-Aug-2011
This is an update of a Cochrane Review first published in The Cochrane Library in Issue 1, 2003. - Steroids, radiotherapy, chemotherapy and stents for superior vena caval obstruction in carcinoma of the bronchus
Cochrane Systematic Reviews, 9-Mar-2015
Superior vena caval obstruction (SVCO) is an uncommon manifestation of carcinoma of the bronchus characterised by neck swelling and distended veins over the chest. Treatment options include radiotherapy, chemotherapy, steroids and insertion of an expandab - Stimulant laxatives for constipation and soiling in children
Cochrane Systematic Reviews, 16-Jun-2008
Constipation is extremely common in childhood and may lead to overflow soiling/encopresis. Standard treatment of the more severe case is to empty the bowels of impacted faeces by the use of oral or rectal laxatives and then maintain regular bowel movement - Stopping long-acting beta2-agonists (LABA) for adults with asthma well controlled by LABA and inhaled corticosteroids
Cochrane Systematic Reviews, 12-Jun-2015
Poorly controlled asthma often leads to preventable exacerbations that require additional medications, as well as unscheduled hospital and clinic visits. - Stopping long-acting beta2-agonists (LABA) for children with asthma well controlled on LABA and inhaled corticosteroids
Cochrane Systematic Reviews, 5-Dec-2017
Asthma is the most common chronic medical condition among children and is one of the most common causes of hospitalisation and medical visits. Poorly controlled asthma often leads to preventable exacerbations that require additional medications, hospital - Strabismus surgery before versus after completion of amblyopia therapy in children
Cochrane Systematic Reviews, 13-Oct-2014
Normal visual development occurs when the brain is able to integrate the visual input from each of the two eyes to form a single three-dimensional image. The process of development of complete three-dimensional vision begins at birth and is almost complet - Strategies for detecting colon cancer in patients with inflammatory bowel disease
Cochrane Systematic Reviews, 23-Sep-2017
Patients with longstanding ulcerative colitis and colonic Crohn's disease have an increased risk of colorectal cancer (CRC) compared with the general population. This review assessed the evidence that endoscopic surveillance may prolong life by allowing e - Strategies for improving postpartum contraceptive use: evidence from non-randomized studies
Cochrane Systematic Reviews, 25-Nov-2014
Nearly two-thirds of women in their first postpartum year have an unmet need for family planning. Adolescents often have repeat pregnancies within a year of giving birth. Women may receive counseling on family planning both antepartum and postpartum. Deci - Strategies for improving the acceptability and acceptance of the copper intrauterine device
Cochrane Systematic Reviews, 10-Feb-2012
Intrauterine devices (IUDs) are highly effective and are the most widely used reversible contraceptive method in the world. However, in developed countries IUDs are among the least common methods of contraception used. We evaluated the effect of intervent
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