- Antiretroviral regimens for patients with HIV who fail first-line antiretroviral therapy
Cochrane Systematic Reviews, 19-Jan-2011
Highly active antiretroviral therapy has reduced the morbidity and mortality of patients with HIV/AIDS. A common first-line ART regimen in low-resource settings includes a non-nucleoside reverse transcriptase inhibitor (NNRTI) and two nucleoside reverse t - Antiretroviral therapy (ART) for treating HIV infection in ART-eligible pregnant women
Cochrane Systematic Reviews, 5-May-2010
This systematic review focuses on antiretroviral therapy (ART) for treating human immunodeficiency virus (HIV) infection in ART-eligible pregnant women. Mother-to-child transmission (MTCT) is the primary means by which children worldwide acquire HIV infec - Antiretroviral therapy for prevention of HIV transmission in HIV-discordant couples
Cochrane Systematic Reviews, 26-Mar-2013
Antiretroviral drugs have been shown to reduce risk of mother-to-child transmission of human immunodeficiency virus (HIV) and are also widely used for post-exposure prophylaxis for parenteral and sexual exposures. Sexual transmission may be lower in coupl - Antiretrovirals for reducing the risk of mother-to-child transmission of HIV infection
Cochrane Systematic Reviews, 13-Jun-2011
Antiretroviral drugs reduce viral replication and can reduce mother-to-child transmission of HIV either by lowering plasma viral load in pregnant women or through post-exposure prophylaxis in their newborns. In rich countries, highly active antiretroviral - Antiseptics for burns
Cochrane Systematic Reviews, 23-Nov-2017
Burn wounds cause high levels of morbidity and mortality worldwide. People with burns are particularly vulnerable to infections; over 75% of all burn deaths (after initial resuscitation) result from infection. Antiseptics are topical agents that act to pr - Antispasmodics for labour
Cochrane Systematic Reviews, 17-May-2013
Prolonged labour can lead to increased maternal and neonatal mortality and morbidity due to increased risks of maternal exhaustion, postpartum haemorrhage and sepsis, fetal distress and asphyxia and requires early detection and appropriate clinical respon - Anti‐spasticity agents for multiple sclerosis
Cochrane Systematic Reviews, 17-Sep-2008
Spasticity is a common problem in multiple sclerosis (MS) patients causing pain, spasms, loss of function and difficulties in nursing care. A variety of oral and parenteral medications are available. - Antistaphylococcal immunoglobulins to prevent staphylococcal infection in very low birth weight infants
Cochrane Systematic Reviews, 17-Feb-2009
Nosocomial infection is a major problem affecting the immediate health and long-term outcome of preterm and very low birth weight neonates. More than half of these infections are caused by staphylococci. Various type specific antibodies targeted at differ - Antistreptococcal interventions for guttate and chronic plaque psoriasis
Cochrane Systematic Reviews, 6-Mar-2019
Guttate psoriasis is a distinctive acute form of psoriasis which characteristically occurs in children and young adults. It is closely associated with preceding streptococcal sore throat or tonsillitis. Some authorities have claimed that ordinary (chronic - Antistreptococcal interventions for guttate and chronic plaque psoriasis
Cochrane Systematic Reviews, 4-Mar-2019
Psoriasis is a chronic skin disease that affects approximately two per cent of the general population. Plaque psoriasis is the most common form: it usually appears as raised, red patches of inflamed skin, covered with silvery white scales. The patches oft - Antithrombin for respiratory distress syndrome in preterm infants
Cochrane Systematic Reviews, 24-Jan-2010
Acquired Antithrombin (AT) deficiency is a common and prognostically important finding in sick preterm infants with respiratory distress syndrome (RDS). It has been hypothesised that AT concentrate may improve clinical outcomes in preterm infants with RDS - Antithrombin for the prevention of intraventricular hemorrhage in very preterm infants
Cochrane Systematic Reviews, 21-Mar-2016
Preterm birth remains the major risk factor for the development of intraventricular hemorrhage, an injury that occurs in 25% of very low birth weight infants. Intraventricular hemorrhage is thought to be venous in origin and intrinsic thromboses in the ge - Antithrombin III for critically ill patients
Cochrane Systematic Reviews, 13-Dec-2018
Critical illness is associated with uncontrolled inflammation and vascular damage which can result in multiple organ failure and death. Antithrombin III (AT III) is an anticoagulant with anti-inflammatory properties but the efficacy and any harmful effect - Antithrombotic agents for preventing thrombosis after infrainguinal arterial bypass surgery
Cochrane Systematic Reviews, 21-Apr-2014
Peripheral arterial disease (PAD) is frequently treated by either an infrainguinal autologous (using the patient's own veins) or synthetic graft bypass. The rate of occlusion of the graft after one year is between 12% and 60%. To prevent occlusion, patien - Antithrombotic drugs for carotid artery dissection
Cochrane Systematic Reviews, 6-Mar-2011
Extracranial internal carotid artery dissection (eICAD) is a leading cause of stroke in younger patients. - Antithrombotic therapy for improving maternal or infant health outcomes in women considered at risk of placental dysfunction
Cochrane Systematic Reviews, 17-Jul-2013
Pregnancy complications such as pre-eclampsia and eclampsia, intrauterine growth restriction and placental abruption are thought to have a common origin related to abnormalities in the development and function of the placenta. - Antithrombotic treatment after stroke due to intracerebral haemorrhage
Cochrane Systematic Reviews, 24-May-2017
Survivors of stroke due to intracerebral haemorrhage (ICH) are at risk of thromboembolism. Antithrombotic (antiplatelet or anticoagulant) treatments may lower the risk of thromboembolism after ICH, but they may increase the risks of bleeding. - Antithyroid drug regimen for treating Graves' hyperthyroidism
Cochrane Systematic Reviews, 10-Nov-2009
Antithyroid drugs are widely used in the therapy of hyperthyroidism. There are wide variations in the dose, regimen or duration of treatment used by health professionals. - Anti‐TNF agents for paediatric psoriasis
Cochrane Systematic Reviews, 1-May-2019
Psoriasis is a chronic skin disease that may develop at any age. Estimates for the United States and Europe suggest that psoriasis accounts for 4% of skin diseases in children. In most cases, the condition is mild and can be treated with creams. However, - Anti‐TNF‐α treatment for pelvic pain associated with endometriosis
Cochrane Systematic Reviews, 31-May-2013
Endometriosis is a chronic, recurring condition that can develop during the reproductive years. It is characterised by the development of endometrial tissue outside the uterine cavity. It is the most common cause of pelvic pain in women. This endometrial
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