- Antipsychotic medication for early episode schizophrenia
Cochrane Systematic Reviews, 16-Feb-2017
Long-term treatment with antipsychotic medications in early episode schizophrenia spectrum disorders is common, but both short and long-term effects on the illness are unclear. There have been numerous suggestions that people with early episodes of schizo - Antipsychotic medication for elderly people with schizophrenia
Cochrane Systematic Reviews, 25-Jan-2006
A large and growing number of older people across the world suffer from schizophrenia. Recommendations for their treatment are largely based on data extrapolated from studies of the use of antipsychotic medications in younger populations. In addition most - Antipsychotic medication versus placebo for people with both schizophrenia and learning disability
Cochrane Systematic Reviews, 17-Dec-2012
Antipsychotic medication is the standard treatment for people with learning disability and schizophrenia. - Antipsychotic medications for cocaine dependence
Cochrane Systematic Reviews, 19-Mar-2016
Cocaine dependence is a public health problem characterised by recidivism and a host of medical and psychosocial complications. Cocaine dependence remains a disorder for which no pharmacological treatment of proven efficacy exists. - Antipsychotic reduction and/or cessation and antipsychotics as specific treatments for tardive dyskinesia
Cochrane Systematic Reviews, 6-Feb-2018
Since the 1950s antipsychotic medication has been extensively used to treat people with chronic mental illnesses such as schizophrenia. These drugs, however, have also been associated with a wide range of adverse effects, including movement disorders such - Antipsychotic switching for people with schizophrenia who have neuroleptic-induced weight or metabolic problems
Cochrane Systematic Reviews, 24-Jan-2013
Weight gain is common for people with schizophrenia and this has serious implications for a patient's health and well being. Switching strategies have been recommended as a management option. - Antipsychotics for acute and chronic pain in adults
Cochrane Systematic Reviews, 29-Aug-2013
This is an updated version of the original Cochrane review published in Issue 4, 2008. The role of antipsychotics as adjuvant analgesics is a subject of longstanding controversy. Neuroleptanalgesia (that is a state of quiescence, altered awareness, and an - Antipsychotics for agitation and psychosis in people with Alzheimer's disease and vascular dementia
Cochrane Systematic Reviews, 17-Dec-2021
Typical and atypical antipsychotics are widely used to treat agitation and psychosis in dementia. However, whether or not they are beneficial is uncertain. Some trials have yielded negative results and effectiveness may be outweighed by harms. - Antipsychotics for fibromyalgia in adults
Cochrane Systematic Reviews, 2-Jun-2016
This review is one of a series on drugs used to treat fibromyalgia. Fibromyalgia is a clinically well-defined chronic condition of unknown aetiology characterised by chronic widespread pain that often co-exists with sleep problems and fatigue. It affects - Antipsychotics for treatment of delirium in hospitalised non‐ICU patients
Cochrane Systematic Reviews, 18-Jun-2018
Guidelines suggest limited and cautious use of antipsychotics for treatment of delirium where nonpharmacological interventions have failed and symptoms remain distressing or dangerous, or both. It is unclear how well these recommendations are supported by - Antipyretic measures for treating fever in malaria
Cochrane Systematic Reviews, 12-Sep-2012
Fever is common in malaria, and drugs and sponging are widely used for symptomatic relief. Some researchers have suggested that fever reduction may prolong malaria illness. - Antiretroviral interventions for preventing breast milk transmission of HIV
Cochrane Systematic Reviews, 28-Sep-2014
An estimated 260,000 children under the age of 15 years acquired HIV infection in 2012. As much as 42% of mother-to-child transmission is related to breastfeeding. Antiretroviral prophylaxis for mothers or infants has the potential to prevent mother-to-ch - Antiretroviral post‐exposure prophylaxis (PEP) for occupational HIV exposure
Cochrane Systematic Reviews, 24-Jan-2007
Populations such as healthcare workers (HCWs), injection drug users (IDUs), and people engaging in unprotected sex are all at risk of being infected with the human immunodeficiency virus (HIV). Animal models show that after initial exposure, HIV replicate - Antiretroviral pre-exposure prophylaxis (PrEP) for preventing HIV in high-risk individuals
Cochrane Systematic Reviews, 10-Nov-2012
More than 30 years into the global HIV/AIDS epidemic, infection rates remain alarmingly high, with over 2.7 million people becoming infected every year. There is a need for HIV prevention strategies that are more effective. Oral antiretroviral pre-exposur - Antiretroviral regimens for patients with HIV who fail first-line antiretroviral therapy
Cochrane Systematic Reviews, 19-Jan-2011
Highly active antiretroviral therapy has reduced the morbidity and mortality of patients with HIV/AIDS. A common first-line ART regimen in low-resource settings includes a non-nucleoside reverse transcriptase inhibitor (NNRTI) and two nucleoside reverse t - Antiretroviral therapy (ART) for treating HIV infection in ART-eligible pregnant women
Cochrane Systematic Reviews, 5-May-2010
This systematic review focuses on antiretroviral therapy (ART) for treating human immunodeficiency virus (HIV) infection in ART-eligible pregnant women. Mother-to-child transmission (MTCT) is the primary means by which children worldwide acquire HIV infec - Antiretroviral therapy for prevention of HIV transmission in HIV-discordant couples
Cochrane Systematic Reviews, 26-Mar-2013
Antiretroviral drugs have been shown to reduce risk of mother-to-child transmission of human immunodeficiency virus (HIV) and are also widely used for post-exposure prophylaxis for parenteral and sexual exposures. Sexual transmission may be lower in coupl - Antiretrovirals for reducing the risk of mother-to-child transmission of HIV infection
Cochrane Systematic Reviews, 13-Jun-2011
Antiretroviral drugs reduce viral replication and can reduce mother-to-child transmission of HIV either by lowering plasma viral load in pregnant women or through post-exposure prophylaxis in their newborns. In rich countries, highly active antiretroviral - Anti‐seizure medications for Lennox‐Gastaut syndrome
Cochrane Systematic Reviews, 7-Apr-2021
Lennox-Gastaut syndrome (LGS) is an age-specific epilepsy syndrome characterised by multiple seizure types, including drop seizures. LGS has a characteristic electroencephalogram, an onset before age eight years and an association with drug resistance. - Antiseptics for burns
Cochrane Systematic Reviews, 23-Nov-2017
Burn wounds cause high levels of morbidity and mortality worldwide. People with burns are particularly vulnerable to infections; over 75% of all burn deaths (after initial resuscitation) result from infection. Antiseptics are topical agents that act to pr
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