- Treatment for epilepsy in pregnancy: neurodevelopmental outcomes in the child
Cochrane Systematic Reviews, 23-Oct-2014
Accumulating evidence suggests an association between prenatal exposure to antiepileptic drugs (AEDs) and increased risk of both physical anomalies and neurodevelopmental impairment. Neurodevelopmental impairment is characterised by either a specific defi - Treatment for familial amyotrophic lateral sclerosis/motor neuron disease
Cochrane Systematic Reviews, 16-Jan-2011
Amyotrophic lateral sclerosis (ALS), also known as motor neuron disease (MND), is a rare neurodegenerative disease. Approximately 5% to 7% of ALS/MND patients report a family history of a similarly affected relative. Superoxide dismutase-1 gene mutations - Treatment for femoral pseudoaneurysms
Cochrane Systematic Reviews, 28-Nov-2013
Femoral pseudoaneurysms may complicate up to 8% of vascular interventional procedures. Small pseudoaneurysms can spontaneously clot, but sometimes definitive treatment is needed. Surgery has traditionally been considered the 'gold standard' treatment, alt - Treatment for Fisher syndrome, Bickerstaff's brainstem encephalitis and related disorders
Cochrane Systematic Reviews, 10-Nov-2009
Fisher syndrome is one of the regional variants of Guillain-Barré syndrome, characterised by impairment of eye movements (ophthalmoplegia), incoordination (ataxia) and loss of tendon reflexes (areflexia). It can occur in more limited forms, and may overla - Treatment for hepatitis C virus-associated mixed cryoglobulinaemia
Cochrane Systematic Reviews, 26-Apr-2018
Hepatitis C virus (HCV)-associated mixed cryoglobulinaemia is the manifestation of an inflammation of small and medium-sized vessels produced by a pathogenic IgM with rheumatoid factor activity generated by an expansion of B-cells. The immune complexes fo - Treatment for hepatorenal syndrome in people with decompensated liver cirrhosis: a network meta-analysis
Cochrane Systematic Reviews, 26-Nov-2019
Hepatorenal syndrome is defined as renal failure in people with cirrhosis in the absence of other causes. In addition to supportive treatment such as albumin to restore fluid balance, the other potential treatments include systemic vasoconstrictor drugs ( - Treatment for HIV-associated cryptococcal meningitis
Cochrane Systematic Reviews, 24-Jul-2018
Cryptococcal meningitis is a severe fungal infection that occurs primarily in the setting of advanced immunodeficiency and remains a major cause of HIV-related deaths worldwide. The best induction therapy to reduce mortality from HIV-associated cryptococc - Treatment for idiopathic and hereditary neuralgic amyotrophy (brachial neuritis)
Cochrane Systematic Reviews, 4-Oct-2011
Neuralgic amyotrophy (also know as Parsonage-Turner syndrome or brachial plexus neuritis) is a distinct peripheral nervous system disorder characterised by episodes (attacks) of extreme neuropathic pain and rapid multifocal weakness and atrophy in the upp - Treatment for inclusion body myositis
Cochrane Systematic Reviews, 8-Jul-2015
Inclusion body myositis (IBM) is a late-onset inflammatory muscle disease (myopathy) associated with progressive proximal and distal limb muscle atrophy and weakness. Treatment options have attempted to target inflammatory and atrophic features of this co - Treatment for inhalant dependence and abuse
Cochrane Systematic Reviews, 25-Oct-2010
Inhalants are being abused by large numbers of people throughout the world, particularly socio-economically disadvantaged children and adolescents. The neuropsychological effects of acute and chronic inhalant abuse include motor impairment, alterations in - Treatment for Lambert-Eaton myasthenic syndrome
Cochrane Systematic Reviews, 16-Jan-2011
Lambert-Eaton myasthenic syndrome (LEMS) is an autoimmune disorder of neuromuscular transmission. Treatments attempt to overcome the harmful autoimmune process, or improve residual neuromuscular transmission - Treatment for leiomyosarcoma and leiomyoma in children with HIV infection
Cochrane Systematic Reviews, 14-Apr-2010
Smooth muscle tumour (SMT) composed of leiomyoma and leiomyosarcoma recently has been described in many HIV-infected children. Leiomyosarcoma has become the second most frequent malignancy in children with HIV infection or other immunodeficiency diseases - Treatment for meralgia paraesthetica
Cochrane Systematic Reviews, 18-Apr-2013
Meralgia paraesthetica is a clinical syndrome for which a number of treatments are in common use, including conservative measures, injection of corticosteroid with local anaesthetic and surgery. We aimed to examine the evidence for the relative efficacy o - Treatment for Methaqualone dependence in adults
Cochrane Systematic Reviews, 27-Mar-2008
Methaqualone is a potent quinazoline, a class of sedative-hypnotics, that has a high potential for abuse. While the oral use of methaqualone (Quaalude, Mandrax) has waned in western countries since the mid-late 1980's, the practice of smoking methaqualone - Treatment for mitochondrial disorders
Cochrane Systematic Reviews, 15-Mar-2012
Mitochondrial respiratory chain disorders are the most prevalent group of inherited neurometabolic diseases. They present with central and peripheral neurological features usually in association with other organ involvement including the eye, the heart, t - Treatment for osteoporosis in people with ß-thalassaemia
Cochrane Systematic Reviews, 3-Mar-2016
Osteoporosis is a systemic skeletal disease characterized by low bone mass and micro-architectural deterioration of bone tissue with a consequent increase in bone fragility and susceptibility to fracture. Osteoporosis represents an important cause of morb - Treatment for paraneoplastic neuropathies
Cochrane Systematic Reviews, 12-Nov-2012
It is not unusual to observe peripheral nervous system involvement in people with tumours outside the nervous system. Any part of the peripheral nervous system can be involved, from sensory and motor neurons to nerve roots and plexuses, from distal trunks - Treatment for periodic paralysis
Cochrane Systematic Reviews, 28-Apr-2008
Primary periodic paralyses are rare inherited muscle diseases characterised by episodes of flaccid weakness affecting one or more limbs, lasting several hours to several days, caused by mutations in skeletal muscle channel genes. - Treatment for peritoneal dialysis-associated peritonitis
Cochrane Systematic Reviews, 20-Apr-2014
Peritonitis is a common complication of peritoneal dialysis (PD) that is associated with significant morbidity including death, hospitalisation, and need to change from PD to haemodialysis. Treatment is aimed to reduce morbidity and recurrence. This is an - Treatment for POEMS (polyneuropathy, organomegaly, endocrinopathy, M-protein, and skin changes) syndrome
Cochrane Systematic Reviews, 16-May-2012
POEMS (polyneuropathy, organomegaly, endocrinopathy, M-protein, and skin changes) syndrome is a rare cause of demyelinating and axonal mixed neuropathy with monoclonal plasma cell proliferative disorder and multiorgan involvement. The pathogenesis of POEM
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