- Transdermal nicotine for induction of remission in ulcerative colitis
Cochrane Systematic Reviews, 19-Jun-2008
Ulcerative colitis is largely a disease of nonsmokers. Intermittent smokers often experience improvement in their symptoms while smoking. Nonsmokers with ulcerative colitis who begin smoking may go into remission. Randomized controlled trials were develop - Transfer of preterm infants from incubator to open cot at lower versus higher body weight
Cochrane Systematic Reviews, 7-Dec-2011
A key criterion for discharging preterm infants home from nurseries is their ability to maintain temperature once transferred from incubators to open cots. The timing of transfer is important given the preterm infant's immature thermoregulatory mechanisms - Transfusion of red blood cells stored for shorter versus longer duration for all conditions
Cochrane Systematic Reviews, 22-Dec-2018
Red blood cell (RBC) transfusion is a common treatment for anaemia in many conditions. The safety and efficacy of transfusing RBC units that have been stored for different durations before a transfusion is a current concern. The duration of storage for a - Transfusion thresholds and other strategies for guiding allogeneic red blood cell transfusion
Cochrane Systematic Reviews, 11-Oct-2016
There is considerable uncertainty regarding the optimal haemoglobin threshold for the use of red blood cell (RBC) transfusions in anaemic patients. Blood is a scarce resource, and in some countries, transfusions are less safe than others because of a lack - Transient elastography for diagnosis of stages of hepatic fibrosis and cirrhosis in people with alcoholic liver disease
Cochrane Systematic Reviews, 22-Jan-2015
The presence and progression of hepatic (liver) fibrosis into cirrhosis is a prognostic variable having impact on survival in people with alcoholic liver disease. Liver biopsy, although an invasive method, is the recommended 'reference standard' for diagn - Transition of care for adolescents from paediatric services to adult health services
Cochrane Systematic Reviews, 29-Apr-2016
There is evidence that the process of transition from paediatric (child) to adult health services is often associated with deterioration in the health of adolescents with chronic conditions.Transitional care is the term used to describe services that seek - Transmyocardial laser revascularization versus medical therapy for refractory angina
Cochrane Systematic Reviews, 12-Apr-2016
This is an update of a review previously published in 2009. Chronic angina and advanced forms of coronary disease are increasingly more frequent. In spite of the improvement in the efficacy of available revascularization treatments, a subgroup of patients - Transparent Cap Colonoscopy versus Standard Colonoscopy to Improve Caecal Intubation
Cochrane Systematic Reviews, 7-Nov-2012
Colonoscopy is considered the gold-standard investigation for screening and diagnosis of colorectal cancer. It is also becoming increasingly desirable for assessment, management, diagnosis and follow-up of other colorectal diseases, such as inflammatory b - Transperitoneal versus retroperitoneal approach for elective open abdominal aortic aneurysm repair
Cochrane Systematic Reviews, 1-Feb-2016
There has been extensive debate in the surgical literature regarding the optimum surgical access approach to the infrarenal abdominal aorta during an operation to repair an abdominal aortic aneurysm. The published trials comparing retroperitoneal (RP) and - Transperitoneal versus retroperitoneal laparoscopic adrenalectomy for adrenal tumours in adults
Cochrane Systematic Reviews, 28-Dec-2018
Laparoscopic adrenalectomy is an accepted treatment worldwide for adrenal gland disease in adults. The transperitoneal approach is more common. The retroperitoneal approach may be preferred, to avoid entering the peritoneum, but no clear advantage has bee - Transplacental versus direct fetal corticosteroid treatment for accelerating fetal lung maturation where there is a risk of preterm birth
Cochrane Systematic Reviews, 12-Jun-2018
Despite major advances in medical technology, the incidence of preterm birth remains high. The use of antenatal corticosteroid administered transplacentally, by intramuscular injection to women at risk of preterm birth, has reduced the incidence of respir - Transpyloric versus gastric tube feeding for preterm infants
Cochrane Systematic Reviews, 18-Jan-2013
Enteral feeding tubes for preterm infants may be placed in the stomach (gastric tube feeding) or in the upper small bowel (transpyloric tube feeding). There are potential advantages and disadvantages to both routes. - Transradial versus transfemoral approach for diagnostic coronary angiography and percutaneous coronary intervention in people with coronary artery disease
Cochrane Systematic Reviews, 17-Apr-2018
Cardiovascular disease (CVD) is the major cause of mortality worldwide. Coronary artery disease (CAD) contributes to half of mortalities caused by CVD. The mainstay of management of CAD is medical therapy and revascularisation. Revascularisation can be ac - Transtheoretical model stages of change for dietary and physical exercise modification in weight loss management for overweight and obese adults
Cochrane Systematic Reviews, 3-Feb-2014
Obesity is a global public health threat. The transtheoretical stages of change (TTM SOC) model has long been considered a useful interventional approach in lifestyle modification programmes, but its effectiveness in producing sustainable weight loss in o - Transurethral radiofrequency collagen denaturation for the treatment of women with urinary incontinence
Cochrane Systematic Reviews, 18-Mar-2015
Transurethral radiofrequency collagen denaturation is a relatively novel, minimally invasive device-based intervention used to treat individuals with urinary incontinence (UI). No systematic review of the evidence supporting its use has been published to - Transvaginal mesh or grafts compared with native tissue repair for vaginal prolapse
Cochrane Systematic Reviews, 8-Nov-2017
A wide variety of grafts have been introduced with the aim of improving the outcomes of traditional native tissue repair (colporrhaphy) for vaginal prolapse. - Transverse verses midline incisions for abdominal surgery
Cochrane Systematic Reviews, 6-Sep-2011
The choice of surgical incision in the abdomen is determined by access. It has been suggested that other parameters such as recovery and complication rate may be influenced by utilising a transverse or oblique rather than a midline incision. However, ther - Trastuzumab containing regimens for early breast cancer
Cochrane Systematic Reviews, 12-Mar-2012
Approximately one-fifth of women who develop early breast cancer have HER2-positive tumours, which if untreated, have a worse prognosis than HER2-negative tumours. Trastuzumab is a selective treatment targeting the HER2 pathway. Although the results on ef - Trastuzumab-containing regimens for metastatic breast cancer
Cochrane Systematic Reviews, 14-May-2014
Patients with breast cancer are classified as having cells that over-express the human epidermal growth factor receptor 2 (known as HER2-positive) or not (HER2-negative). Typically, patients with HER2-positive disease have a worse prognosis. Trastuzumab i - Trazodone for agitation in dementia
Cochrane Systematic Reviews, 13-May-2008
Behavioural and psychiatric disturbances affect at least 50% of people with Alzheimer's disease and other dementias. Neuroleptic drugs are extensively prescribed to treat behavioural manifestations of dementia in spite of only modest efficacy and a high f
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