- Single versus two layer suturing for closing the uterine incision at Caesarean section
Cochrane Systematic Reviews, 3-May-2008
A single layer closure might save operating time, disrupt less tissue, introduce less foreign material into the wound, and thus result in less post operative morbidity. - Single, double or multiple‐injection techniques for non‐ultrasound guided axillary brachial plexus block in adults undergoing surgery of the lower arm
Cochrane Systematic Reviews, 2-Sep-2016
Regional anaesthesia comprising axillary block of the brachial plexus is a common anaesthetic technique for distal upper limb surgery. This is an update of a review first published in 2006 and previously updated in 2011 and 2013. - Single‐dose intravenous diclofenac for acute postoperative pain in adults
Cochrane Systematic Reviews, 28-Aug-2018
Postoperative administration of non-steroidal anti-inflammatory drugs (NSAIDs) reduces patient opioid requirements and, in turn, reduces the incidence and severity of opioid-induced adverse events (AEs). - Single‐dose intravenous ibuprofen for acute postoperative pain in adults
Cochrane Systematic Reviews, 9-Sep-2021
Postoperative administration of non-steroidal anti-inflammatory drugs (NSAIDs) reduces patient opioid requirements and, in turn, may reduce the incidence and severity of opioid-induced adverse events (AEs). - Single‐dose intravenous ketorolac for acute postoperative pain in adults
Cochrane Systematic Reviews, 17-May-2021
Postoperative pain is common and may be severe. Postoperative administration of non-steroidal anti-inflammatory drugs (NSAIDs) reduces patient opioid requirements and, in turn, may reduce the incidence and severity of opioid-induced adverse events (AEs). - Single‐dose intravesical chemotherapy after nephroureterectomy for upper tract urothelial carcinoma
Cochrane Systematic Reviews, 18-May-2019
Single-dose, postoperative intravesical chemotherapy reduces the risk of bladder cancer recurrence after transurethral resection of bladder tumours. However, there is limited evidence whether single-dose intravesical chemotherapy is similarly effective at - Single‐incision sling operations for urinary incontinence in women
Cochrane Systematic Reviews, 26-Jul-2017
Urinary incontinence has been shown to affect up to 50% of women. Studies in the USA have shown that up to 80% of these women have an element of stress urinary incontinence. This imposes significant health and economic burden on society and the women affe - Sinonasal debridement versus no debridement for the postoperative care of patients undergoing endoscopic sinus surgery
Cochrane Systematic Reviews, 5-Nov-2018
Endoscopic sinus surgery (ESS) is often recommended for symptomatic patients with recurrent acute or chronic rhinosinusitis who have failed conservative treatment. Postoperative care has been felt to be critical for both maintaining the surgical patency o - Siponimod for multiple sclerosis
Cochrane Systematic Reviews, 16-Nov-2021
Multiple sclerosis (MS) is a chronic immune-mediated disease of the central nervous system, with an unpredictable course. Current MS therapies such as disease-modifying therapies focus on treating exacerbations, preventing new exacerbations and avoiding t - Six months therapy for tuberculous meningitis
Cochrane Systematic Reviews, 1-Sep-2016
Tuberculous meningitis (TBM) is the main form of tuberculosis that affects the central nervous system and is associated with high rates of death and disability. Most international guidelines recommend longer antituberculous treatment (ATT) regimens for TB - Six‐month therapy for abdominal tuberculosis
Cochrane Systematic Reviews, 1-Nov-2016
Tuberculosis (TB) of the gastrointestinal tract and any other organ within the abdominal cavity is abdominal TB, and most guidelines recommend the same six-month regimen used for pulmonary TB for people with this diagnosis. However, some physicians are co - Skin antisepsis for reducing central venous catheter-related infections
Cochrane Systematic Reviews, 12-Jul-2016
The central venous catheter (CVC) is a device used for many functions, including monitoring haemodynamic indicators and administering intravenous medications, fluids, blood products and parenteral nutrition. However, as a foreign object, it is susceptible - Skin care interventions in infants for preventing eczema and food allergy
Cochrane Systematic Reviews, 14-Nov-2022
Eczema and food allergy are common health conditions that usually begin in early childhood and often occur in the same people. They can be associated with an impaired skin barrier in early infancy. It is unclear whether trying to prevent or reverse an imp - Skin grafting and tissue replacement for treating foot ulcers in people with diabetes
Cochrane Systematic Reviews, 11-Feb-2016
Foot ulceration is a major problem in people with diabetes and is the leading cause of hospitalisation and limb amputations. Skin grafts and tissue replacements can be used to reconstruct skin defects for people with diabetic foot ulcers in addition to pr - Skin grafting for venous leg ulcers
Cochrane Systematic Reviews, 31-Jan-2013
Venous leg ulceration is a recurrent, chronic, disabling condition. It affects up to one in 100 people at some time in their lives. Standard treatments are simple dressings and compression bandages or stockings. Sometimes, despite treatment, ulcers remain - Skin patch and vaginal ring versus combined oral contraceptives for contraception
Cochrane Systematic Reviews, 30-Apr-2013
The delivery of combination contraceptive steroids from a transdermal contraceptive patch or a contraceptive vaginal ring offers potential advantages over the traditional oral route. The transdermal patch and vaginal ring could require a lower dose due to - Skin preparation for preventing infection following caesarean section
Cochrane Systematic Reviews, 25-Jun-2020
The risk of maternal mortality and morbidity is higher after caesarean section than for vaginal birth. With increasing rates of caesarean section, it is important to minimise risks to the mother as much as possible. This review focused on different skin p - Skin preparation with alcohol versus alcohol followed by any antiseptic for preventing bacteraemia or contamination of blood for transfusion
Cochrane Systematic Reviews, 12-Feb-2015
Blood for transfusion may become contaminated at any point between collection and transfusion and may result in bacteraemia (the presence of bacteria in the blood), severe illness or even death for the blood recipient. Donor arm skin is one potential sour - Skin‐to‐skin care for procedural pain in neonates
Cochrane Systematic Reviews, 16-Feb-2017
Skin-to-skin care (SSC), often referred to as 'kangaroo care' (KC) due to its similarity with marsupial behaviour of ventral maternal-infant contact, is one non-pharmacological intervention for pain control in infants. - Sleep positioning systems for children with cerebral palsy
Cochrane Systematic Reviews, 2-Nov-2015
Sleep positioning systems can be prescribed for children with cerebral palsy to help reduce or prevent hip migration, provide comfort to ease pain and/or improve sleep. As sleep disturbance is common in children with developmental disabilities, with impac
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