- Protease-modulating matrix treatments for healing venous leg ulcers
Cochrane Systematic Reviews, 20-Apr-2017
Venous leg ulcers (VLUs) are open skin wounds on the lower leg that occur because of poor blood flow in the veins of the leg; leg ulcers can last from weeks to years, and are both painful and costly. Prevalence in the UK is about 2.9 cases per 10,000 peop - Protein containing synthetic surfactant versus animal derived surfactant extract for the prevention and treatment of respiratory distress syndrome
Cochrane Systematic Reviews, 23-Sep-2008
Respiratory distress syndrome (RDS) is a significant cause of morbidity and mortality in preterm infants. RDS is caused by a deficiency, dysfunction, or inactivation of pulmonary surfactant. Numerous surfactants of either animal extract or synthetic desig - Protein restriction for diabetic renal disease
Cochrane Systematic Reviews, 5-Nov-2008
Diabetic renal disease (diabetic nephropathy) is a leading cause of end-stage renal failure. Once the process has started, it cannot be reversed by glycaemic control, but progression might be slowed by control of blood pressure and protein restriction. - Protocolized versus non-protocolized weaning for reducing the duration of invasive mechanical ventilation in newborn infants
Cochrane Systematic Reviews, 21-Mar-2016
Mechanical ventilation is a life-saving intervention for critically ill newborn infants with respiratory failure admitted to a neonatal intensive care unit (NICU). Ventilating newborn infants can be challenging due to small tidal volumes, high breathing f - Proton pump inhibitor treatment for acute peptic ulcer bleeding
Cochrane Systematic Reviews, 13-Apr-2010
Randomised controlled trials (RCTs) evaluating the clinical effect of proton pump inhibitors (PPIs) in peptic ulcer (PU) bleeding yield conflicting results. - Provider training and experience for people living with HIV/AIDS
Cochrane Systematic Reviews, 30-Jun-2011
The complexity of HIV/AIDS raises challenges for the effective delivery of care. It is important to ensure that the expertise and experience of care providers is of high quality. Training and experience of HIV/AIDS providers may impact not only individual - Providing physicians with feedback on medication adherence for people with chronic diseases taking long-term medication
Cochrane Systematic Reviews, 4-Jan-2018
Poor medication adherence decreases treatment efficacy and worsens clinical outcomes, but average rates of adherence to long-term pharmacological treatments for chronic illnesses are only about 50%. Interventions for improving medication adherence largely - Provision of respiratory support compared to no respiratory support before cord clamping for preterm infants
Cochrane Systematic Reviews, 7-Mar-2018
Placental transfusion (by means of delayed cord clamping (DCC), cord milking, or cord stripping) confers benefits for preterm infants. It is not known if providing respiratory support to preterm infants before cord clamping improves outcomes. - Psychoanalytic/psychodynamic psychotherapy for children and adolescents who have been sexually abused
Cochrane Systematic Reviews, 31-Jul-2013
The sexual abuse of children and adolescents is a significant worldwide problem. It is associated with a wide variety of negative psychological, social and physical consequences for the victims. These effects can often be seen immediately following sexual - Psychoeducation for siblings of people with severe mental illness
Cochrane Systematic Reviews, 21-Apr-2015
Many people with severe mental illness (SMI) have siblings. Siblings are often both natural agents to promote service users’ recovery and vulnerable to mental ill health due to the negative impact of psychosis within the family. Despite a wealth of resear - Psychological and behavioural treatments for adults with non-epileptic attack disorder
Cochrane Systematic Reviews, 11-Feb-2014
Psychogenic non-epileptic seizures, also known as non-epileptic attack disorder (NEAD), have the outward appearance of epilepsy in the absence of physiological or electroencephalographic correlates. Non-epileptic seizures can occur in isolation or in comb - Psychological and pharmacological interventions for depression in patients with coronary artery disease
Cochrane Systematic Reviews, 9-Aug-2011
Depression occurs frequently in patients with coronary artery disease (CAD) and is associated with a poor prognosis. - Psychological and pharmacological interventions for depression in patients with diabetes mellitus and depression
Cochrane Systematic Reviews, 14-Nov-2012
Depression occurs frequently in patients with diabetes mellitus and is associated with a poor prognosis. - Psychological interventions for adults who have sexually offended or are at risk of offending
Cochrane Systematic Reviews, 14-Nov-2012
Sexual offending is a legal construct that overlaps, but is not entirely congruent with, clinical constructs of disorders of sexual preference. Sexual offending is both a social and a public health issue. Victim surveys illustrate high incidence and preva - Psychological interventions for coronary heart disease
Cochrane Systematic Reviews, 28-Apr-2017
Coronary heart disease (CHD) is the most common cause of death globally, although mortality rates are falling. Psychological symptoms are prevalent for people with CHD, and many psychological treatments are offered following cardiac events or procedures w - Psychological interventions for depression in adolescent and adult congenital heart disease
Cochrane Systematic Reviews, 23-Oct-2013
Adult and adolescent congenital heart disease is increasing in prevalence as better medical care means more children are surviving to adulthood. People with chronic disease often also experience depression. There are several non-pharmacological treatments - Psychological interventions for diabetes-related distress in adults with type 2 diabetes mellitus
Cochrane Systematic Reviews, 25-Oct-2017
Many adults with type 2 diabetes mellitus (T2DM) experience a psychosocial burden and mental health problems associated with the disease. Diabetes-related distress (DRD) has distinct effects on self-care behaviours and disease control. Improving DRD in ad - Psychological interventions for multiple sclerosis
Cochrane Systematic Reviews, 17-Sep-2008
The unpredictable, variable nature of Multiple Sclerosis (MS), and the possibility of increasing disability, means that a diagnosis can have substantial psychological consequences. - Psychological interventions for overweight or obesity
Cochrane Systematic Reviews, 6-May-2014
Overweight and obesity are global health problems which are increasing throughout the industrialised world. If left unchecked, they will continue to contribute to the ever increasing non communicable disease burden. - Psychological interventions for post-traumatic stress disorder (PTSD) in people with severe mental illness
Cochrane Systematic Reviews, 20-Jan-2017
Increasing evidence indicates that individuals who develop severe mental illness (SMI) are also vulnerable to developing post-traumatic stress disorder (PTSD), due to increased risk of exposure to traumatic events and social adversity. The effectiveness o
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