- Antimicrobial drugs for treating methicillin-resistant Staphylococcus aureus colonization
Cochrane Systematic Reviews, 17-Jun-2008
Eradication strategies for methicillin-resistant Staphylococcus aureus (MRSA) are variable. We sought to summarize the evidence for use of antimicrobial agents to eradicate MRSA. - Antimicrobial lock solutions for preventing catheter-related infections in haemodialysis
Cochrane Systematic Reviews, 30-Mar-2018
Patients undergoing haemodialysis (HD) through a central venous catheter (CVC) are exposed to several risks, being a catheter-related infection (CRI) and a CVC lumen thrombosis among the most serious. Standard of care regarding CVCs includes their sealing - Antimicrobial mouthwashes (gargling) and nasal sprays administered to patients with suspected or confirmed COVID‐19 infection to improve patient outcomes and to protect healthcare workers treating them
Cochrane Systematic Reviews, 16-Sep-2020
COVID-19 infection poses a serious risk to patients and – due to its contagious nature – to those healthcare workers (HCWs) treating them. If the mouth and nose of patients with infection are irrigated with antimicrobial solutions, this may help the patie - Antimicrobial mouthwashes (gargling) and nasal sprays to protect healthcare workers when undertaking aerosol‐generating procedures (AGPs) on patients without suspected or confirmed COVID‐19 infection
Cochrane Systematic Reviews, 16-Sep-2020
COVID-19 infection poses a serious risk to patients and – due to its contagious nature – to those healthcare workers (HCWs) treating them. The risks of transmission of infection are greater when a patient is undergoing an aerosol-generating procedure (AGP - Antimicrobial prophylaxis for colorectal surgery
Cochrane Systematic Reviews, 9-May-2014
Research shows that administration of prophylactic antibiotics before colorectal surgery prevents postoperative surgical wound infection. The best antibiotic choice, timing of administration and route of administration remain undetermined. - Antimicrobial therapy for chronic bacterial prostatitis
Cochrane Systematic Reviews, 2-Aug-2013
Chronic bacterial prostatitis (CBP) is frequently diagnosed in men of fertile age, and is characterized by a disabling array of symptoms, including pain in the pelvic area (for example, perineum, testicles), voiding symptoms (increased frequency and urgen - Antimicrobial-impregnated central venous catheters for prevention of catheter-related bloodstream infection in newborn infants
Cochrane Systematic Reviews, 24-Sep-2015
Central venous catheter-related bloodstream infection is an important cause of mortality and morbidity in newborn infants cared for in neonatal units. Potential strategies to prevent these infections include the use of central venous catheters impregnated - Antimicrobials for treating symptomatic non‐typhoidal Salmonella infection
Cochrane Systematic Reviews, 14-Nov-2012
Non-typhoidal Salmonella (NTS) commonly causes diarrhoea, and is usually self-limiting, although sometimes people become ill with sepsis and dehydration. Routine antibiotic use for this infection could result in persistent colonization and the spread of r - Antimotility agents for chronic diarrhoea in people with HIV/AIDS
Cochrane Systematic Reviews, 13-Aug-2008
AIDS-related diarrhoea is a common cause of morbidity and mortality in HIV positive individuals, especially in the sub-Saharan Africa where 70% of deaths from HIV occur. It often compromises quality of life both in those receiving antiretroviral therapy ( - Antioxidant supplementation for lung disease in cystic fibrosis
Cochrane Systematic Reviews, 3-Oct-2019
Airway infection leads to progressive damage of the lungs in cystic fibrosis (CF) and oxidative stress has been implicated in the etiology. Supplementation of antioxidant micronutrients (vitamin E, vitamin C, beta-carotene and selenium) or N-acetylcystein - Antioxidant supplements for liver diseases
Cochrane Systematic Reviews, 15-Feb-2011
Several liver diseases have been associated with oxidative stress. Accordingly, antioxidants have been suggested as potential therapeutics for various liver diseases. The evidence supporting these suggestions is equivocal. - Antioxidant supplements for non‐alcoholic fatty liver disease and/or steatohepatitis
Cochrane Systematic Reviews, 24-Jan-2007
Non-alcoholic fatty liver disease (NAFLD) is characterised by fatty deposition in the hepatocytes of patients with minimal or no alcohol intake and without other known cause. NAFLD includes a wide spectrum of histologic abnormalities ranging from hepatic - Antioxidant supplements for preventing gastrointestinal cancers
Cochrane Systematic Reviews, 25-May-2008
Oxidative stress may cause gastrointestinal cancers. The evidence on whether antioxidant supplements are effective in preventing gastrointestinal cancers is contradictory. - Antioxidant supplements for prevention of mortality in healthy participants and patients with various diseases
Cochrane Systematic Reviews, 14-Mar-2012
Our systematic review has demonstrated that antioxidant supplements may increase mortality. We have now updated this review. - Antioxidant treatment for amyotrophic lateral sclerosis or motor neuron disease
Cochrane Systematic Reviews, 24-Jan-2007
Free radical accumulation and oxidative stress have been proposed as contributing to the progression of amyotrophic lateral sclerosis (or motor neuron disease). A range of antioxidant medications have been studied. This is an updated review. - Antioxidant treatments for schizophrenia
Cochrane Systematic Reviews, 19-Jan-2016
There is accumulating evidence that progressive changes in brain structure and function take place as schizophrenia unfolds. Among many possible candidates, oxidative stress may be one of the mediators of neuroprogression, grey matter loss and subsequent - Antioxidant vitamin and mineral supplements for preventing age‐related macular degeneration
Cochrane Systematic Reviews, 30-Jul-2017
There is inconclusive evidence from observational studies to suggest that people who eat a diet rich in antioxidant vitamins (carotenoids, vitamins C, and E) or minerals (selenium and zinc) may be less likely to develop age-related macular degeneration (A - Antioxidant vitamin and mineral supplements for slowing the progression of age‐related macular degeneration
Cochrane Systematic Reviews, 30-Jul-2017
It has been proposed that antioxidants may prevent cellular damage in the retina by reacting with free radicals that are produced in the process of light absorption. Higher dietary levels of antioxidant vitamins and minerals may reduce the risk of progres - Antioxidant vitamin supplementation for preventing and slowing the progression of age-related cataract
Cochrane Systematic Reviews, 3-May-2012
Age-related cataract is a major cause of visual impairment in the elderly. Oxidative stress has been implicated in its formation and progression. Antioxidant vitamin supplementation has been investigated in this context. - Antioxidants for chronic kidney disease
Cochrane Systematic Reviews, 17-Oct-2012
Chronic kidney disease (CKD) is a significant risk factor for premature cardiovascular disease and death. Increased oxidative stress in people with CKD has been implicated as a potential causative factor for some cardiovascular diseases. Antioxidant thera
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