- Sclerotherapy versus beta‐blockers for primary prophylaxis of oesophageal variceal bleeding in children and adolescents with chronic liver disease or portal vein thrombosis
Cochrane Systematic Reviews, 10-Jan-2020
Portal hypertension commonly accompanies advanced liver disease and often gives rise to life-threatening complications, including bleeding (haemorrhage) from oesophageal and gastrointestinal varices. Variceal bleeding commonly occurs in children with chro - Sclerotherapy versus sham or no intervention for primary prophylaxis of oesophageal variceal bleeding in children with chronic liver disease or portal vein thrombosis
Cochrane Systematic Reviews, 5-Mar-2020
Portal hypertension commonly accompanies advanced liver disease and often gives rise to life-threatening complications, including bleeding (haemorrhage) from oesophageal and gastrointestinal varices. Variceal bleeding commonly occurs in children with chro - Scopolamine (hyoscine) for preventing and treating motion sickness
Cochrane Systematic Reviews, 15-Jun-2011
This is an update of a Cochrane Review first published in The Cochrane Library in Issue 3, 2004 and previously updated in 2007 and 2009. - Screening and case finding instruments for depression
Cochrane Systematic Reviews, 19-Oct-2005
Screening or case finding instruments have been advocated as a simple, quick and inexpensive method to improve detection and management of depression in non-specialist settings, such as primary care and the general hospital. However, screening/case findin - Screening and subsequent management for thyroid dysfunction pre‐pregnancy and during pregnancy for improving maternal and infant health
Cochrane Systematic Reviews, 21-Sep-2015
Thyroid dysfunction pre-pregnancy and during pregnancy (both hyper- and hypothyroidism) is associated with increased risk of adverse outcomes for mothers and infants in the short- and long-term. Managing the thyroid dysfunction (e.g. thyroxine for hypothy - Screening for abdominal aortic aneurysm
Cochrane Systematic Reviews, 27-Jan-2011
Abdominal aortic aneurysm (AAA) is found in 5% to 10% of men aged 65 to 79 years. The major complication is rupture which presents as a surgical emergency. The mortality after rupture is high, 80% for patients reaching hospital and 50% for those undergoin - Screening for aspiration risk associated with dysphagia in acute stroke
Cochrane Systematic Reviews, 18-Oct-2021
Stroke can affect people’s ability to swallow, resulting in passage of some food and drink into the airway. This can cause choking, chest infection, malnutrition and dehydration, reduced rehabilitation, increased risk of anxiety and depression, longer hos - Screening for breast cancer with mammography
Cochrane Systematic Reviews, 4-Jun-2013
A variety of estimates of the benefits and harms of mammographic screening for breast cancer have been published and national policies vary. - Screening for colorectal cancer using the faecal occult blood test, Hemoccult
Cochrane Systematic Reviews, 24-Jan-2007
Colorectal cancer is a leading cause of morbidity and mortality, especially in the Western world. The human and financial costs have prompted considerable research to evaluate screening tests to detect the cancer at an early curable stage. Tests that have - Screening for genital chlamydia infection
Cochrane Systematic Reviews, 13-Sep-2016
Genital infections caused by Chlamydia trachomatis are the most prevalent bacterial sexually transmitted infection worldwide. Screening of sexually active young adults to detect and treat asymptomatic infections might reduce chlamydia transmission and pre - Screening for gestational diabetes mellitus based on different risk profiles and settings for improving maternal and infant health
Cochrane Systematic Reviews, 3-Aug-2017
Gestational diabetes mellitus (GDM) is a form of diabetes that occurs in pregnancy. Although GDM usually resolves following birth, it is associated with significant morbidities for mothers and their infants in the short and long term. There is strong evid - Screening for lung cancer
Cochrane Systematic Reviews, 21-Jun-2013
This is an updated version of the original review published in The Cochrane Library in 1999 and updated in 2004 and 2010. Population-based screening for lung cancer has not been adopted in the majority of countries. However it is not clear whether sputum - Screening for nasopharyngeal cancer
Cochrane Systematic Reviews, 6-Nov-2015
Nasopharyngeal cancer is endemic in a few well-defined populations. The prognosis for advanced nasopharyngeal cancer is poor, but early-stage disease is curable and a high survival rate can be achieved. Screening for early-stage disease could lead to impr - Screening for oesophageal cancer
Cochrane Systematic Reviews, 31-Oct-2012
Oesophageal cancer is a global heath problem. The prognosis for advanced oesophageal cancer is generally unfavourable, but early-stage asymptomatic oesophageal cancer is basically curable and could achieve better survival rates. The two most commonly used - Screening for peripheral arterial disease
Cochrane Systematic Reviews, 7-Apr-2014
In the general population, up to 10% of people younger than 70 years and 15% to 20% of people older than 70 years have peripheral arterial disease (PAD). Symptomatic and asymptomatic PAD has an estimated prevalence of 13% in the over 50 years age group. H - Screening for prevention of optic nerve damage due to chronic open angle glaucoma
Cochrane Systematic Reviews, 18-Oct-2006
Open angle glaucoma (OAG) is a primary, progressive optic neuropathy; the onset is without symptoms and progression occurs silently until the advanced stages of the disease, when it affects central vision. The blindness caused by OAG is irreversible. It h - Screening for prostate cancer
Cochrane Systematic Reviews, 31-Jan-2013
Any form of screening aims to reduce disease-specific and overall mortality, and to improve a person's future quality of life. Screening for prostate cancer has generated considerable debate within the medical and broader community, as demonstrated by the - Screening for reducing morbidity and mortality in malignant melanoma
Cochrane Systematic Reviews, 3-Jun-2019
Screening for malignant melanoma has the potential to reduce morbidity and mortality from the disease through earlier detection, as prognosis is closely associated with the thickness of the lesion at the time of diagnosis. However, there are also potentia - Screening for testicular cancer
Cochrane Systematic Reviews, 15-Mar-2011
Testicular cancer commonly affects men aged between 20 and 35 years. Screening for testicular cancer may reduce both morbidity and mortality, yet the effectiveness of any method is unknown. Equally, screening may also promote treatment procedures that are - Screening for type 2 diabetes mellitus
Cochrane Systematic Reviews, 29-May-2020
Diabetes mellitus, a metabolic disorder characterised by hyperglycaemia and associated with a heavy burden of microvascular and macrovascular complications, frequently remains undiagnosed. Screening of apparently healthy individuals may lead to early dete
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