- Sequential combination of glucocorticosteroids and alfa interferon versus alfa interferon alone for HBeAg‐positive chronic hepatitis B
Cochrane Systematic Reviews, 20-Jul-2005
Chronic hepatitis B has serious effects on morbidity and mortality. Alfa interferon has been shown to increase the rates of HBeAg-clearance as well as seroconversion to anti-HBe, but response rates are unsatisfactory. Glucocorticosteroid pretreatment may - Sequential inactivated (IPV) and live oral (OPV) poliovirus vaccines for preventing poliomyelitis
Cochrane Systematic Reviews, 5-Dec-2019
Poliomyelitis mainly affects unvaccinated children under five years of age, causing irreversible paralysis or even death. The oral polio vaccine (OPV) contains live attenuated virus, which can, in rare cases, cause a paralysis known as vaccine-associated - Sequential versus standard triple first‐line therapy for Helicobacter pylori eradication
Cochrane Systematic Reviews, 28-Jun-2016
Non-bismuth quadruple sequential therapy (SEQ) comprising a first induction phase with a dual regimen of amoxicillin and a proton pump inhibitor (PPI) for five days followed by a triple regimen phase with a PPI, clarithromycin and metronidazole for anothe - Serenoa repens for benign prostatic hyperplasia
Cochrane Systematic Reviews, 12-Dec-2012
Benign prostatic hyperplasia (BPH) is a nonmalignant enlargement of the prostate, which can lead to obstructive and irritative lower urinary tract symptoms (LUTS). The pharmacologic use of plants and herbs (phytotherapy) for the treatment of LUTS associat - Serotonin and noradrenaline reuptake inhibitors (SNRI) for stress urinary incontinence in adults
Cochrane Systematic Reviews, 5-Nov-2008
To date, standard recommendations for the management of stress urinary incontinence (SUI) would be either pelvic floor muscle training (PFMT) or surgery. A new form of drug treatment with a serotonin-noradrenaline reuptake inhibitor (SNRI), duloxetine, ma - Serotonin and noradrenaline reuptake inhibitors (SNRIs) for fibromyalgia
Cochrane Systematic Reviews, 28-Feb-2018
Fibromyalgia is a clinically defined chronic condition of unknown etiology characterized by chronic widespread pain that often co-exists with sleep disturbances, cognitive dysfunction and fatigue. People with fibromyalgia often report high disability leve - Serotonin receptor antagonists for highly emetogenic chemotherapy in adults
Cochrane Systematic Reviews, 16-Feb-2016
Serotonin receptor antagonists (5-HT3 RAs) are used to control chemotherapy-induced emesis. Although they have the same general mechanism of action (blockade of serotonin receptors), they have different chemical structures and may have different effects. - Sertindole for schizophrenia
Cochrane Systematic Reviews, 20-Jul-2005
Sertindole is an atypical antipsychotic, which is thought to give a lower incidence of extrapyramidal side effects at clinically effective doses than typical antipsychotic drugs. In December 1998, Lundbeck Ltd., the manufacturers of sertindole, voluntaril - Sertindole versus other atypical antipsychotics for schizophrenia
Cochrane Systematic Reviews, 15-Apr-2009
In many countries of the industrialised world second generation (atypical) antipsychotics have become the first line drug treatment for people with schizophrenia. The question as to whether and, if so, how much the effects of the various second generation - Sertraline versus other antidepressive agents for depression
Cochrane Systematic Reviews, 14-Apr-2010
The National Institute for Health and Clinical Excellence clinical practice guideline on the treatment of depressive disorder recommended that selective serotonin reuptake inhibitors should be the first-line option when drug therapy is indicated for a dep - Serum amylase and lipase and urinary trypsinogen and amylase for diagnosis of acute pancreatitis
Cochrane Systematic Reviews, 21-Apr-2017
The treatment of people with acute abdominal pain differs if they have acute pancreatitis. It is important to know the diagnostic accuracy of serum amylase, serum lipase, urinary trypsinogen-2, and urinary amylase for the diagnosis of acute pancreatitis, - Serum C‐reactive protein, procalcitonin, and lactate dehydrogenase for the diagnosis of pancreatic necrosis
Cochrane Systematic Reviews, 21-Apr-2017
The treatment of people with pancreatic necrosis differs from that of people with oedematous pancreatitis. It is important to know the diagnostic accuracy of serum C-reactive protein (CRP), serum procalcitonin, and serum lactate dehydrogenase (LDH) as a t - Serum or plasma ferritin concentration as an index of iron deficiency and overload
Cochrane Systematic Reviews, 24-May-2021
Reference standard indices of iron deficiency and iron overload are generally invasive, expensive, and can be unpleasant or occasionally risky. Ferritin is an iron storage protein and its concentration in the plasma or serum reflects iron stores; low ferr - Service organisation for the secondary prevention of ischaemic heart disease in primary care
Cochrane Systematic Reviews, 17-Mar-2010
Ischaemic heart disease (IHD) is a major cause of mortality and morbidity and its prevalence is set to increase. Secondary prevention aims to prevent subsequent acute events in people with established IHD. While the benefits of individual medical and life - Services for helping acute stroke patients avoid hospital admission
Cochrane Systematic Reviews, 28-Nov-2011
Stroke patients are usually admitted to hospital for their acute care and rehabilitation. Services to help acute stroke patients avoid admission to hospital ('hospital-at-home') have now been developed. - Servo-control for maintaining abdominal skin temperature at 36C in low birth weight infants
Cochrane Systematic Reviews, 23-Apr-2008
Randomized trials have shown that the neonatal mortality rate of low birth-weight babies can be reduced by keeping them warm. For low birth-weight babies nursed in incubators, warm conditions may be achieved either by heating the air to a desired temperat - Setting and organization of care for persons living with HIV/AIDS
Cochrane Systematic Reviews, 19-Jul-2006
Treating the world's 40.3 million persons currently infected with HIV/AIDS is an international responsibility that involves unprecedented organizational challenges. Key issues include whether care should be concentrated or decentralized, what type and mix - Setting and techniques for monitoring blood pressure during pregnancy
Cochrane Systematic Reviews, 23-Jul-2020
Regular blood pressure (BP) measurement is crucial for the diagnosis and management of hypertensive disorders in pregnancy, such as pre-eclampsia. BP can be measured in various settings, such as conventional clinics or self-measurement at home, and with d - Severe fatigue after treatment for childhood cancer
Cochrane Systematic Reviews, 3-Mar-2020
Treatment strategies for childhood cancer are improving, resulting in higher survival rates. However, the consequences of childhood cancer do not end with the successful completion of cancer treatment. Most patients will develop late effects after cessati - Sexual counselling for sexual problems in patients with cardiovascular disease
Cochrane Systematic Reviews, 24-Feb-2016
Sexual problems are common among people with cardiovascular disease. Although clinical guidelines recommend sexual counselling for patients and their partners, there is little evidence on its effectiveness.
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