- Pharmacological interventions for benzodiazepine mono-dependence management in outpatient settings
Cochrane Systematic Reviews, 18-Jun-2013
The items with X are considered "more relevant", that is the review has to stick to them to allow publication. The others have to be considered as strong suggestions to improve the readability and clarity of the review, but the reviewers can consider if - Pharmacological interventions for clozapine-induced hypersalivation
Cochrane Systematic Reviews, 18-Jan-2012
Clozapine is widely used for people with schizophrenia. Although agranulocytosis, weight gain, and cardiac problems are serious problems associated with its use, hypersalivation, sometimes of a gross and socially unacceptable quantity, is also common (30- - Pharmacological interventions for clozapine-induced sinus tachycardia
Cochrane Systematic Reviews, 27-May-2016
Clozapine is an efficacious treatment for treatment-resistant schizophrenia; however its use can be limited by side effect intolerability. Sinus tachycardia is a common adverse event associated with clozapine treatment. Various pharmacological treatments - Pharmacological interventions for cognitive decline in people with Down syndrome
Cochrane Systematic Reviews, 29-Oct-2015
People with Down syndrome are vulnerable to developing dementia at an earlier age than the general population. Alzheimer's disease and cognitive decline in people with Down syndrome can place a significant burden on both the person with Down syndrome and - Pharmacological interventions for drug-using offenders
Cochrane Systematic Reviews, 2-Jun-2015
The review represents one in a family of four reviews focusing on a range of different interventions for drug-using offenders. This specific review considers pharmacological interventions aimed at reducing drug use or criminal activity, or both, for illic - Pharmacological interventions for generalised itching (not caused by systemic disease or skin lesions) in pregnancy
Cochrane Systematic Reviews, 18-Feb-2016
Generalised itching is one of the most common dermatological symptoms in pregnant women. Having itchy skin during pregnancy may be very frustrating and can lead to poor sleep, exhaustion and impaired quality of life. There is a need for a systematic revie - Pharmacological interventions for hypertension in children
Cochrane Systematic Reviews, 25-Jan-2014
Hypertension is a major risk factor for stroke, coronary artery disease and kidney damage in adults. There is a paucity of data on the long-term sequelae of persistent hypertension in children, but it is known that children with hypertension have evidence - Pharmacological interventions for non-alcohol related fatty liver disease (NAFLD)
Cochrane Systematic Reviews, 12-Apr-2017
Non-alcohol related fatty liver disease (commonly called non-alcoholic fatty liver disease (NAFLD)) is liver steatosis in the absence of significant alcohol consumption, use of hepatotoxic medication, or other disorders affecting the liver such as hepatit - Pharmacological interventions for pain in children and adolescents with life-limiting conditions
Cochrane Systematic Reviews, 23-Jun-2017
Pain is one of the most common symptoms in children and young people (CYP) with life-limiting conditions (LLCs) which include a wide range of diagnoses including cancer. The current literature indicates that pain is not well managed, however the evidence - Pharmacological interventions for pain in patients with temporomandibular disorders
Cochrane Systematic Reviews, 6-Sep-2010
Temporomandibular disorders (TMD) are a group of disorders affecting the temporomandibular joints and the muscles of mastication. TMDs are treated with a wide range of drugs. The extent to which the use of these drugs is based upon evidence is unknown. - Pharmacological interventions for pain relief during orthodontic treatment
Cochrane Systematic Reviews, 20-Dec-2017
Pain is a common side effect of orthodontic treatment. It increases in proportion to the amount of force applied to the teeth, and the type of orthodontic appliance used can affect the intensity of the pain. Pain during orthodontic treatment has been show - Pharmacological interventions for preventing dry mouth and salivary gland dysfunction following radiotherapy
Cochrane Systematic Reviews, 31-Jul-2017
Salivary gland dysfunction is an 'umbrella' term for the presence of either xerostomia (subjective sensation of dryness), or salivary gland hypofunction (reduction in saliva production). It is a predictable side effect of radiotherapy to the head and neck - Pharmacological interventions for preventing post-traumatic stress disorder (PTSD)
Cochrane Systematic Reviews, 7-Jul-2014
Post-traumatic stress disorder (PTSD) is a debilitating disorder which, after a sufficient delay, may be diagnosed amongst individuals who respond with intense fear, helplessness or horror to traumatic events. There is some evidence that the use of pharma - Pharmacological interventions for prevention or treatment of postoperative pain in people undergoing laparoscopic cholecystectomy
Cochrane Systematic Reviews, 28-Mar-2014
While laparoscopic cholecystectomy is generally considered less painful than open surgery, pain is one of the important reasons for delayed discharge after day-surgery and overnight stay following laparoscopic cholecystectomy. The safety and effectiveness - Pharmacological interventions for primary biliary cholangitis
Cochrane Systematic Reviews, 12-Apr-2017
Primary biliary cholangitis (previously primary biliary cirrhosis) is a chronic liver disease caused by the destruction of small intra-hepatic bile ducts resulting in stasis of bile (cholestasis), liver fibrosis, and liver cirrhosis. The optimal pharmacol - Pharmacological interventions for recurrent abdominal pain (RAP) and irritable bowel syndrome (IBS) in childhood
Cochrane Systematic Reviews, 17-Feb-2014
Between 4% and 25% of school-age children complain of recurrent abdominal pain (RAP) of sufficient severity to interfere with daily activities. For the majority, no organic cause for their pain can be found on physical examination or investigation and alt - Pharmacological interventions for recurrent abdominal pain in childhood
Cochrane Systematic Reviews, 6-Mar-2017
Between 4% and 25% of school-aged children at some stage complain of recurrent abdominal pain (RAP) of sufficient severity to interfere with their daily lives. When no clear organic cause is found, the children are managed with reassurance and simple meas - Pharmacological interventions for self-harm in adults
Cochrane Systematic Reviews, 3-Jul-2015
Self-harm (SH; intentional self-poisoning or self-injury) is common, often repeated, and strongly associated with suicide. This is an update of a broader Cochrane review on psychosocial and pharmacological treatments for deliberate SH, first published in - Pharmacological interventions for self-injurious behaviour in adults with intellectual disabilities
Cochrane Systematic Reviews, 28-Mar-2013
Self-injurious behaviour among people with intellectual disability is relatively common and often persistent. Self-injurious behaviour continues to present a challenge to clinicians. It remains poorly understood and difficult to ameliorate despite advance - Pharmacological interventions for sleepiness and sleep disturbances caused by shift work
Cochrane Systematic Reviews, 13-Jun-2014
Shift work results in sleep-wake disturbances, which cause sleepiness during night shifts and reduce sleep length and quality in daytime sleep after the night shift. In its serious form it is also called shift work sleep disorder. Various pharmacological
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