- Retinoids for preventing the progression of cervical intra-epithelial neoplasia
Cochrane Systematic Reviews, 1-Jun-2016
Invasive cervical carcinoma is preceded by a precancerous phase, cervical intra-epithelial neoplasia (CIN), which can be detected on cervical smears and confirmed by colposcopy and biopsy. Moderate and severe cases of intra-epithelial neoplasia (CIN2 and - Retroperitoneal drainage versus no drainage after pelvic lymphadenectomy for the prevention of lymphocyst formation in women with gynaecological malignancies
Cochrane Systematic Reviews, 29-Jun-2017
This is an updated version of an original Cochrane review published in Issue 6, 2014. Pelvic lymphadenectomy is associated with significant complications including lymphocyst formation and related morbidities. Retroperitoneal drainage using suction drains - Retroperitoneal versus transperitoneal approach for elective open abdominal aortic aneurysm repair
Cochrane Systematic Reviews, 21-Jun-2021
There has been extensive debate in the surgical literature regarding the optimum surgical access approach to the infrarenal abdominal aorta during an operation to repair an abdominal aortic aneurysm. The published trials comparing retroperitoneal (RP) and - Return‐to‐work coordination programmes for improving return to work in workers on sick leave
Cochrane Systematic Reviews, 30-Mar-2017
To limit long-term sick leave and associated consequences, insurers, healthcare providers and employers provide programmes to facilitate disabled people's return to work. These programmes include a variety of coordinated and individualised interventions. - Retzius‐sparing versus standard robotic‐assisted laparoscopic prostatectomy for the treatment of clinically localized prostate cancer.
Cochrane Systematic Reviews, 18-Aug-2020
Robotic-assisted laparoscopic prostatectomy (RALP) is widely used to surgically treat clinically localized prostate cancer. It is typically performed using an approach (standard RALP) that mimics open retropubic prostatectomy by dissecting the so-called s - Revascularisation of the left subclavian artery for thoracic endovascular aortic repair
Cochrane Systematic Reviews, 27-Apr-2016
Controversy exists as to whether revascularisation of the left subclavian artery (LSA) confers improved outcomes in patients undergoing thoracic endovascular aortic repair (TEVAR). Even though preemptive revascularisation of the LSA has theoretical advant - Rheum officinale (a traditional Chinese medicine) for chronic kidney disease
Cochrane Systematic Reviews, 11-Jul-2012
Chronic kidney disease (CKD) is a major public health issue worldwide. Standard therapies to delay CKD progression include dietary protein restriction and administration of angiotensin-converting enzyme inhibitors (ACEi) and angiotensin receptor blockers - Rho kinase inhibitor for primary open‐angle glaucoma and ocular hypertension
Cochrane Systematic Reviews, 10-Jun-2022
Glaucoma is a group of optic neuropathies characterized by progressive degeneration of the retinal ganglion cells, axonal loss and irreversible visual field defects. Glaucoma is classified as primary or secondary, and worldwide, primary glaucoma is a lead - Ribavirin for treating Crimean Congo haemorrhagic fever
Cochrane Systematic Reviews, 5-Jun-2018
Crimean Congo haemorrhagic fever (CCHF) is a tick-borne disease that occurs in parts of Asia, Europe and Africa. Since 2000 the infection has caused epidemics in Turkey, Iran, Russia, Uganda and Pakistan. Good-quality general supportive medical care helps - Ribavirin monotherapy for chronic hepatitis C
Cochrane Systematic Reviews, 7-Oct-2009
Hepatitis C is a major cause of liver-related morbidity and mortality. A high proportion of patients never experience symptoms. Peginterferon plus ribavirin is the recommended treatment for chronic hepatitis C. However, ribavirin monotherapy may be consid - Ribavirin plus interferon versus interferon for chronic hepatitis C
Cochrane Systematic Reviews, 20-Jan-2010
Hepatitis C is a major cause of liver-related morbidity and mortality. Standard therapy is ribavirin plus pegylated interferon to achieve undetectable level of virus in the blood, but the effect on clinical outcomes is controversial. - Ribavirin with or without alpha interferon for chronic hepatitis C
Cochrane Systematic Reviews, 20-Oct-2008
Hepatitis C is a major cause of liver-related morbidity and mortality. Ribavirin plus interferon combination therapy is presently considered the optimal treatment of interferon naive patients with chronic hepatitis C, but its role in relapsers and non-res - Rice-based oral rehydration solution for treating diarrhoea
Cochrane Systematic Reviews, 9-Nov-2009
Oral rehydration therapy is used to treat dehydration caused by diarrhoea. However the rehydration solution does not reduce stool loss or length of illness. A solution able to do this may lessen the use of ineffective diarrhoea treatments as well as impro - Rifabutin for treating pulmonary tuberculosis
Cochrane Systematic Reviews, 10-Nov-2009
Rifamycins are an essential component of modern short-course regimens for treating tuberculosis. Rifabutin has favourable pharmacokinetic and pharmacodynamic properties and is less prone to drug-drug interactions than rifampicin. It could contribute to sh - Rifamycins (rifampicin, rifabutin and rifapentine) compared to isoniazid for preventing tuberculosis in HIV-negative people at risk of active TB
Cochrane Systematic Reviews, 28-Jun-2013
Preventing active tuberculosis (TB) from developing in people with latent tuberculosis infection (LTBI) is important for global TB control. Isoniazid (INH) for six to nine months has 60% to 90% protective efficacy, but the treatment period is long, liver - Rigid dressings versus soft dressings for transtibial amputations
Cochrane Systematic Reviews, 17-Jun-2019
Dressings are part of the routine postoperative management of people after transtibial amputation. Two types of dressings are commonly used; soft dressings (e.g. elastic bandages, crepe bandages) and rigid dressings (e.g. non-removable rigid dressings, re - Riluzole for amyotrophic lateral sclerosis (ALS)/motor neuron disease (MND)
Cochrane Systematic Reviews, 14-Mar-2012
Riluzole is approved for the treatment of amyotrophic lateral sclerosis in most countries. Questions persist about its clinical utility because of high cost and modest efficacy. - Rimonabant for overweight or obesity
Cochrane Systematic Reviews, 2-Nov-2008
Worldwide, the prevalence of obesity and overweight in industrialized countries and in a substantial number of developing countries is increasing at an alarming rate. Rimonabant is a selective cannabinoid-1 receptor antagonist that has been investigated f - Rinse‐free hand wash for reducing absenteeism among preschool and school children
Cochrane Systematic Reviews, 9-Apr-2020
Illness-related absenteeism is an important problem among preschool and school children for low-, middle- and high- income countries. Appropriate hand hygiene is one commonly investigated and implemented strategy to reduce the spread of illness and subseq - Risedronate for the primary and secondary prevention of osteoporotic fractures in postmenopausal women
Cochrane Systematic Reviews, 3-May-2022
Osteoporosis is an abnormal reduction in bone mass and bone deterioration leading to increased fracture risk. Risedronate belongs to the bisphosphonate class of drugs which act to inhibit bone resorption by interfering with the activity of osteoclasts. Th
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