- Self-management interventions including action plans for exacerbations versus usual care in patients with chronic obstructive pulmonary disease
Cochrane Systematic Reviews, 4-Aug-2017
Chronic Obstructive Pulmonary Disease (COPD) self-management interventions should be structured but personalised and often multi-component, with goals of motivating, engaging and supporting the patients to positively adapt their behaviour(s) and develop s - Self‐monitoring and self‐management of oral anticoagulation
Cochrane Systematic Reviews, 30-Jun-2016
The introduction of point-of-care devices for the management of patients on oral anticoagulation allows self-testing by the patient at home. Patients who self-test can either adjust their medication according to a pre-determined dose-INR (international no - Self-monitoring of blood glucose in patients with type 2 diabetes mellitus who are not using insulin
Cochrane Systematic Reviews, 5-Apr-2012
Self-monitoring of blood glucose (SMBG) has been found to be effective for patients with type 1 diabetes and for patients with type 2 diabetes using insulin. There is much debate on the effectiveness of SMBG as a tool in the self-management for patients w - Semen preparation techniques for intrauterine insemination
Cochrane Systematic Reviews, 21-Nov-2019
Semen preparation techniques for assisted reproduction, including intrauterine insemination (IUI), were developed to select the motile morphologically normal spermatozoa. The yield of many motile, morphologically normal spermatozoa might influence treatme - Semi‐recumbent position versus supine position for the prevention of ventilator‐associated pneumonia in adults requiring mechanical ventilation
Cochrane Systematic Reviews, 4-Jan-2016
Ventilator-associated pneumonia (VAP) is associated with increased mortality, prolonged length of hospital stay and increased healthcare costs in critically ill patients. Guidelines recommend a semi-recumbent position (30º to 45º) for preventing VAP among - Sensory environment on health-related outcomes of hospital patients
Cochrane Systematic Reviews, 15-Feb-2012
Hospital environments have recently received renewed interest, with considerable investments into building and renovating healthcare estates. Understanding the effectiveness of environmental interventions is important for resource utilisation and providin - Sensory stimulation for brain injured individuals in coma or vegetative state
Cochrane Systematic Reviews, 22-Sep-2008
Coma and vegetative state follow traumatic brain injury in about one out of eight patients, and in patients with non traumatic injury the prognosis is worse. The use of sensory stimulation for coma and vegetative state has gained popularity during the 198 - Sentinel lymph node biopsy followed by lymph node dissection for localised primary cutaneous melanoma
Cochrane Systematic Reviews, 16-Oct-2017
Melanoma is the leading cause of skin cancer-associated mortality. The vast majority of newly diagnosed melanomas are confined to the primary cutaneous site. Surgery represents the mainstay of melanoma treatment. Treatment strategies include wide excision - Sentinel node assessment for diagnosis of groin lymph node involvement in vulval cancer
Cochrane Systematic Reviews, 21-Sep-2016
Vulval cancer is usually treated by wide local excision with removal of groin lymph nodes (inguinofemoral lymphadenectomy) from one or both sides, depending on the tumour location. However, this procedure is associated with significant morbidity. As lymph - Septum resection for women of reproductive age with a septate uterus
Cochrane Systematic Reviews, 4-Mar-2020
Women with a septate uterus are at increased risk for subfertility, recurrent miscarriage, and preterm birth. Restoration of the anatomy of the uterus by hysteroscopic septum resection is an established intervention. This treatment has been assessed mainl - Sequencing of anthracyclines and taxanes in neoadjuvant and adjuvant therapy for early breast cancer
Cochrane Systematic Reviews, 14-Feb-2019
Anthracyclines and taxanes are chemotherapeutic agents widely used in a sequential regimen in the adjuvant and neoadjuvant treatment of early breast cancer to reduce the risk of cancer recurrence. Standard practice is to administer anthracycline-based che - Sequencing of chemotherapy and radiotherapy for early breast cancer
Cochrane Systematic Reviews, 20-Mar-2013
After surgery for localised breast cancer, radiotherapy (RT) improves both local control and breast cancer-specific survival. In patients at risk of harbouring micro-metastatic disease, adjuvant chemotherapy (CT) improves 15-year survival. However, the be - Sequential combination of glucocorticosteroids and alfa interferon versus alfa interferon alone for HBeAg‐positive chronic hepatitis B
Cochrane Systematic Reviews, 8-Nov-2008
Chronic hepatitis B has serious effects on morbidity and mortality. Alfa interferon has been shown to increase the rates of HBeAg-clearance as well as seroconversion to anti-HBe, but response rates are unsatisfactory. Glucocorticosteroid pretreatment may - Sequential inactivated (IPV) and live oral (OPV) poliovirus vaccines for preventing poliomyelitis
Cochrane Systematic Reviews, 4-Dec-2019
Poliomyelitis mainly affects unvaccinated children under five years of age, causing irreversible paralysis or even death. The oral polio vaccine (OPV) contains live attenuated virus, which can, in rare cases, cause a paralysis known as vaccine-associated - Sequential versus standard triple first-line therapy for Helicobacter pylori eradication
Cochrane Systematic Reviews, 25-Jun-2016
Non-bismuth quadruple sequential therapy (SEQ) comprising a first induction phase with a dual regimen of amoxicillin and a proton pump inhibitor (PPI) for five days followed by a triple regimen phase with a PPI, clarithromycin and metronidazole for anothe - Serenoa repens for benign prostatic hyperplasia
Cochrane Systematic Reviews, 31-Oct-2012
Benign prostatic hyperplasia (BPH) is a nonmalignant enlargement of the prostate, which can lead to obstructive and irritative lower urinary tract symptoms (LUTS). The pharmacologic use of plants and herbs (phytotherapy) for the treatment of LUTS associat - Serotonin and noradrenaline reuptake inhibitors (SNRI) for stress urinary incontinence in adults
Cochrane Systematic Reviews, 5-Nov-2008
To date, standard recommendations for the management of stress urinary incontinence (SUI) would be either pelvic floor muscle training (PFMT) or surgery. A new form of drug treatment with a serotonin-noradrenaline reuptake inhibitor (SNRI), duloxetine, ma - Serotonin and noradrenaline reuptake inhibitors (SNRIs) for fibromyalgia
Cochrane Systematic Reviews,
Fibromyalgia is a clinically defined chronic condition of unknown etiology characterized by chronic widespread pain that often co-exists with sleep disturbances, cognitive dysfunction and fatigue. People with fibromyalgia often report high disability leve - Serotonin receptor antagonists for highly emetogenic chemotherapy in adults
Cochrane Systematic Reviews, 16-Feb-2016
Serotonin receptor antagonists (5-HT3 RAs) are used to control chemotherapy-induced emesis. Although they have the same general mechanism of action (blockade of serotonin receptors), they have different chemical structures and may have different effects. - Sertindole for schizophrenia
Cochrane Systematic Reviews, 18-Jan-2011
Sertindole is an atypical antipsychotic, which is thought to give a lower incidence of extrapyramidal side effects at clinically effective doses than typical antipsychotic drugs. In December 1998, Lundbeck Ltd., the manufacturers of sertindole, voluntaril
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