- Antipsychotics for acute and chronic pain in adults
Cochrane Systematic Reviews, 27-Nov-2015
This is an updated version of the original Cochrane review published in Issue 4, 2008. The role of antipsychotics as adjuvant analgesics is a subject of longstanding controversy. Neuroleptanalgesia (that is a state of quiescence, altered awareness, and an - Antipsychotics for fibromyalgia in adults
Cochrane Systematic Reviews, 15-Sep-2016
This review is one of a series on drugs used to treat fibromyalgia. Fibromyalgia is a clinically well-defined chronic condition of unknown aetiology characterised by chronic widespread pain that often co-exists with sleep problems and fatigue. It affects - Antipsychotics for treatment of delirium in hospitalised non-ICU patients
Cochrane Systematic Reviews, 15-Jun-2018
Guidelines suggest limited and cautious use of antipsychotics for treatment of delirium where nonpharmacological interventions have failed and symptoms remain distressing or dangerous, or both. It is unclear how well these recommendations are supported by - Antipyretic measures for treating fever in malaria
Cochrane Systematic Reviews, 25-Jul-2012
Fever is common in malaria, and drugs and sponging are widely used for symptomatic relief. Some researchers have suggested that fever reduction may prolong malaria illness. - Antiretroviral interventions for preventing breast milk transmission of HIV
Cochrane Systematic Reviews, 28-Sep-2014
An estimated 260,000 children under the age of 15 years acquired HIV infection in 2012. As much as 42% of mother-to-child transmission is related to breastfeeding. Antiretroviral prophylaxis for mothers or infants has the potential to prevent mother-to-ch - Antiretroviral post-exposure prophylaxis (PEP) for occupational HIV exposure
Cochrane Systematic Reviews, 12-Apr-2012
Populations such as healthcare workers (HCWs), injection drug users (IDUs), and people engaging in unprotected sex are all at risk of being infected with the human immunodeficiency virus (HIV). Animal models show that after initial exposure, HIV replicate - Antiretroviral pre-exposure prophylaxis (PrEP) for preventing HIV in high-risk individuals
Cochrane Systematic Reviews, 10-Nov-2012
More than 30 years into the global HIV/AIDS epidemic, infection rates remain alarmingly high, with over 2.7 million people becoming infected every year. There is a need for HIV prevention strategies that are more effective. Oral antiretroviral pre-exposur - Antiretroviral regimens for patients with HIV who fail first-line antiretroviral therapy
Cochrane Systematic Reviews, 19-Jan-2011
Highly active antiretroviral therapy has reduced the morbidity and mortality of patients with HIV/AIDS. A common first-line ART regimen in low-resource settings includes a non-nucleoside reverse transcriptase inhibitor (NNRTI) and two nucleoside reverse t - Antiretroviral therapy (ART) for treating HIV infection in ART-eligible pregnant women
Cochrane Systematic Reviews, 5-May-2010
This systematic review focuses on antiretroviral therapy (ART) for treating human immunodeficiency virus (HIV) infection in ART-eligible pregnant women. Mother-to-child transmission (MTCT) is the primary means by which children worldwide acquire HIV infec - Antiretroviral therapy for prevention of HIV transmission in HIV-discordant couples
Cochrane Systematic Reviews, 26-Mar-2013
Antiretroviral drugs have been shown to reduce risk of mother-to-child transmission of human immunodeficiency virus (HIV) and are also widely used for post-exposure prophylaxis for parenteral and sexual exposures. Sexual transmission may be lower in coupl - Antiretrovirals for reducing the risk of mother-to-child transmission of HIV infection
Cochrane Systematic Reviews, 13-Jun-2011
Antiretroviral drugs reduce viral replication and can reduce mother-to-child transmission of HIV either by lowering plasma viral load in pregnant women or through post-exposure prophylaxis in their newborns. In rich countries, highly active antiretroviral - Antiseptics for burns
Cochrane Systematic Reviews, 23-Nov-2017
Burn wounds cause high levels of morbidity and mortality worldwide. People with burns are particularly vulnerable to infections; over 75% of all burn deaths (after initial resuscitation) result from infection. Antiseptics are topical agents that act to pr - Antispasmodics for labour
Cochrane Systematic Reviews, 17-May-2013
Prolonged labour can lead to increased maternal and neonatal mortality and morbidity due to increased risks of maternal exhaustion, postpartum haemorrhage and sepsis, fetal distress and asphyxia and requires early detection and appropriate clinical respon - Anti-spasticity agents for multiple sclerosis
Cochrane Systematic Reviews, 17-Sep-2008
Spasticity is a common problem in multiple sclerosis (MS) patients causing pain, spasms, loss of function and difficulties in nursing care. A variety of oral and parenteral medications are available. - Antistaphylococcal immunoglobulins to prevent staphylococcal infection in very low birth weight infants
Cochrane Systematic Reviews, 17-Feb-2009
Nosocomial infection is a major problem affecting the immediate health and long-term outcome of preterm and very low birth weight neonates. More than half of these infections are caused by staphylococci. Various type specific antibodies targeted at differ - Antistreptococcal interventions for guttate and chronic plaque psoriasis
Cochrane Systematic Reviews, 4-Mar-2019
Psoriasis is a chronic skin disease that affects approximately two per cent of the general population. Plaque psoriasis is the most common form: it usually appears as raised, red patches of inflamed skin, covered with silvery white scales. The patches oft - Antistreptococcal interventions for guttate and chronic plaque psoriasis
Cochrane Systematic Reviews, 6-Mar-2019
Guttate psoriasis is a distinctive acute form of psoriasis which characteristically occurs in children and young adults. It is closely associated with preceding streptococcal sore throat or tonsillitis. Some authorities have claimed that ordinary (chronic - Antithrombin for respiratory distress syndrome in preterm infants
Cochrane Systematic Reviews, 24-Jan-2010
Acquired Antithrombin (AT) deficiency is a common and prognostically important finding in sick preterm infants with respiratory distress syndrome (RDS). It has been hypothesised that AT concentrate may improve clinical outcomes in preterm infants with RDS - Antithrombin for the prevention of intraventricular hemorrhage in very preterm infants
Cochrane Systematic Reviews, 21-Mar-2016
Preterm birth remains the major risk factor for the development of intraventricular hemorrhage, an injury that occurs in 25% of very low birth weight infants. Intraventricular hemorrhage is thought to be venous in origin and intrinsic thromboses in the ge - Antithrombin III for critically ill patients
Cochrane Systematic Reviews, 13-Dec-2018
Critical illness is associated with uncontrolled inflammation and vascular damage which can result in multiple organ failure and death. Antithrombin III (AT III) is an anticoagulant with anti-inflammatory properties but the efficacy and any harmful effect
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